Eintrag weiter verarbeiten
Protein import into the nucleus
Gespeichert in:
| Zeitschriftentitel: | FEBS Letters |
|---|---|
| Personen und Körperschaften: | |
| In: | FEBS Letters, 389, 1996, 1, S. 75-79 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Wiley
|
| Schlagwörter: |
| author_facet |
Schlenstedt, Gabriel Schlenstedt, Gabriel |
|---|---|
| author |
Schlenstedt, Gabriel |
| spellingShingle |
Schlenstedt, Gabriel FEBS Letters Protein import into the nucleus Cell Biology Genetics Molecular Biology Biochemistry Structural Biology Biophysics |
| author_sort |
schlenstedt, gabriel |
| spelling |
Schlenstedt, Gabriel 0014-5793 1873-3468 Wiley Cell Biology Genetics Molecular Biology Biochemistry Structural Biology Biophysics http://dx.doi.org/10.1016/0014-5793(96)00583-2 <jats:p>The transport of proteins from the cytoplasm into the nucleus is a multistep process. The nuclear localization sequence (NLS) of a transport substrate associates with the heterodimeric NLS‐receptor which binds to a subset of proteins of the nuclear pore complex (NPC). Translocation through the NPC is energy‐DApenDAnt and requires the small GTPase Ran. Proteins that interact with Ran in either the GDP‐bound or the GTP‐bound state coordinate transfer through the NPC. Lastly, the NLS‐receptor/substrate complex and Ran reach the nuclear siDA of the NPC where the complex disassembles.</jats:p> Protein import into the nucleus FEBS Letters |
| doi_str_mv |
10.1016/0014-5793(96)00583-2 |
| facet_avail |
Online Free |
| finc_class_facet |
Biologie Chemie und Pharmazie Physik |
| format |
ElectronicArticle |
| fullrecord |
blob:ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAxNi8wMDE0LTU3OTMoOTYpMDA1ODMtMg |
| id |
ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAxNi8wMDE0LTU3OTMoOTYpMDA1ODMtMg |
| institution |
DE-Ch1 DE-L229 DE-D275 DE-Bn3 DE-Brt1 DE-D161 DE-Zwi2 DE-Gla1 DE-Zi4 DE-15 DE-Pl11 DE-Rs1 DE-105 DE-14 |
| imprint |
Wiley, 1996 |
| imprint_str_mv |
Wiley, 1996 |
| issn |
0014-5793 1873-3468 |
| issn_str_mv |
0014-5793 1873-3468 |
| language |
English |
| mega_collection |
Wiley (CrossRef) |
| match_str |
schlenstedt1996proteinimportintothenucleus |
| publishDateSort |
1996 |
| publisher |
Wiley |
| recordtype |
ai |
| record_format |
ai |
| series |
FEBS Letters |
| source_id |
49 |
| title |
Protein import into the nucleus |
| title_unstemmed |
Protein import into the nucleus |
| title_full |
Protein import into the nucleus |
| title_fullStr |
Protein import into the nucleus |
| title_full_unstemmed |
Protein import into the nucleus |
| title_short |
Protein import into the nucleus |
| title_sort |
protein import into the nucleus |
| topic |
Cell Biology Genetics Molecular Biology Biochemistry Structural Biology Biophysics |
| url |
http://dx.doi.org/10.1016/0014-5793(96)00583-2 |
| publishDate |
1996 |
| physical |
75-79 |
| description |
<jats:p>The transport of proteins from the cytoplasm into the nucleus is a multistep process. The nuclear localization sequence (NLS) of a transport substrate associates with the heterodimeric NLS‐receptor which binds to a subset of proteins of the nuclear pore complex (NPC). Translocation through the NPC is energy‐DApenDAnt and requires the small GTPase Ran. Proteins that interact with Ran in either the GDP‐bound or the GTP‐bound state coordinate transfer through the NPC. Lastly, the NLS‐receptor/substrate complex and Ran reach the nuclear siDA of the NPC where the complex disassembles.</jats:p> |
| container_issue |
1 |
| container_start_page |
75 |
| container_title |
FEBS Letters |
| container_volume |
389 |
| format_de105 |
Article, E-Article |
| format_de14 |
Article, E-Article |
| format_de15 |
Article, E-Article |
| format_de520 |
Article, E-Article |
| format_de540 |
Article, E-Article |
| format_dech1 |
Article, E-Article |
| format_ded117 |
Article, E-Article |
| format_degla1 |
E-Article |
| format_del152 |
Buch |
| format_del189 |
Article, E-Article |
| format_dezi4 |
Article |
| format_dezwi2 |
Article, E-Article |
| format_finc |
Article, E-Article |
| format_nrw |
Article, E-Article |
| _version_ |
1792339445914009607 |
| geogr_code |
not assigned |
| last_indexed |
2024-03-01T15:48:15.638Z |
| geogr_code_person |
not assigned |
| openURL |
url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=Protein+import+into+the+nucleus&rft.date=1996-06-24&genre=article&issn=1873-3468&volume=389&issue=1&spage=75&epage=79&pages=75-79&jtitle=FEBS+Letters&atitle=Protein+import+into+the+nucleus&aulast=Schlenstedt&aufirst=Gabriel&rft_id=info%3Adoi%2F10.1016%2F0014-5793%2896%2900583-2&rft.language%5B0%5D=eng |
| SOLR | |
| _version_ | 1792339445914009607 |
| author | Schlenstedt, Gabriel |
| author_facet | Schlenstedt, Gabriel, Schlenstedt, Gabriel |
| author_sort | schlenstedt, gabriel |
| container_issue | 1 |
| container_start_page | 75 |
| container_title | FEBS Letters |
| container_volume | 389 |
| description | <jats:p>The transport of proteins from the cytoplasm into the nucleus is a multistep process. The nuclear localization sequence (NLS) of a transport substrate associates with the heterodimeric NLS‐receptor which binds to a subset of proteins of the nuclear pore complex (NPC). Translocation through the NPC is energy‐DApenDAnt and requires the small GTPase Ran. Proteins that interact with Ran in either the GDP‐bound or the GTP‐bound state coordinate transfer through the NPC. Lastly, the NLS‐receptor/substrate complex and Ran reach the nuclear siDA of the NPC where the complex disassembles.</jats:p> |
| doi_str_mv | 10.1016/0014-5793(96)00583-2 |
| facet_avail | Online, Free |
| finc_class_facet | Biologie, Chemie und Pharmazie, Physik |
| format | ElectronicArticle |
| format_de105 | Article, E-Article |
| format_de14 | Article, E-Article |
| format_de15 | Article, E-Article |
| format_de520 | Article, E-Article |
| format_de540 | Article, E-Article |
| format_dech1 | Article, E-Article |
| format_ded117 | Article, E-Article |
| format_degla1 | E-Article |
| format_del152 | Buch |
| format_del189 | Article, E-Article |
| format_dezi4 | Article |
| format_dezwi2 | Article, E-Article |
| format_finc | Article, E-Article |
| format_nrw | Article, E-Article |
| geogr_code | not assigned |
| geogr_code_person | not assigned |
| id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAxNi8wMDE0LTU3OTMoOTYpMDA1ODMtMg |
| imprint | Wiley, 1996 |
| imprint_str_mv | Wiley, 1996 |
| institution | DE-Ch1, DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-D161, DE-Zwi2, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14 |
| issn | 0014-5793, 1873-3468 |
| issn_str_mv | 0014-5793, 1873-3468 |
| language | English |
| last_indexed | 2024-03-01T15:48:15.638Z |
| match_str | schlenstedt1996proteinimportintothenucleus |
| mega_collection | Wiley (CrossRef) |
| physical | 75-79 |
| publishDate | 1996 |
| publishDateSort | 1996 |
| publisher | Wiley |
| record_format | ai |
| recordtype | ai |
| series | FEBS Letters |
| source_id | 49 |
| spelling | Schlenstedt, Gabriel 0014-5793 1873-3468 Wiley Cell Biology Genetics Molecular Biology Biochemistry Structural Biology Biophysics http://dx.doi.org/10.1016/0014-5793(96)00583-2 <jats:p>The transport of proteins from the cytoplasm into the nucleus is a multistep process. The nuclear localization sequence (NLS) of a transport substrate associates with the heterodimeric NLS‐receptor which binds to a subset of proteins of the nuclear pore complex (NPC). Translocation through the NPC is energy‐DApenDAnt and requires the small GTPase Ran. Proteins that interact with Ran in either the GDP‐bound or the GTP‐bound state coordinate transfer through the NPC. Lastly, the NLS‐receptor/substrate complex and Ran reach the nuclear siDA of the NPC where the complex disassembles.</jats:p> Protein import into the nucleus FEBS Letters |
| spellingShingle | Schlenstedt, Gabriel, FEBS Letters, Protein import into the nucleus, Cell Biology, Genetics, Molecular Biology, Biochemistry, Structural Biology, Biophysics |
| title | Protein import into the nucleus |
| title_full | Protein import into the nucleus |
| title_fullStr | Protein import into the nucleus |
| title_full_unstemmed | Protein import into the nucleus |
| title_short | Protein import into the nucleus |
| title_sort | protein import into the nucleus |
| title_unstemmed | Protein import into the nucleus |
| topic | Cell Biology, Genetics, Molecular Biology, Biochemistry, Structural Biology, Biophysics |
| url | http://dx.doi.org/10.1016/0014-5793(96)00583-2 |