author_facet Gasser, Theo
Rousson, Valentin
Gasser, Theo
Rousson, Valentin
author Gasser, Theo
Rousson, Valentin
spellingShingle Gasser, Theo
Rousson, Valentin
Statistics in Medicine
Modelling neuromotor ratings with floor‐effects
Statistics and Probability
Epidemiology
author_sort gasser, theo
spelling Gasser, Theo Rousson, Valentin 0277-6715 1097-0258 Wiley Statistics and Probability Epidemiology http://dx.doi.org/10.1002/sim.1914 <jats:title>Abstract</jats:title><jats:p>Associated movements (AMs) are a classical diagnostic tool to assess differences between normal children and children with some motor dysfunction. This paper presents a methodology to produce age‐ and gender‐dependent reference‐curves for AMs of normal children, for various tasks of a test battery. Data available consist of separate ratings of duration and extent of AMs, which are ordinal quantities with few levels. Other problems are severe age‐ and gender‐dependent floor‐effects (as well as some ceiling‐effects), leaving little information for analysis at older ages. To get a better scale, we combined the two ordinal ratings into one meaningful and quasi‐continuous quantity referred to as intensity of AMs. In order to solve problems due to floor‐effects, ceiling‐effects and discreteness, we assumed left‐ , right‐ and interval‐censored values, respectively. We considered a censored regression problem and postulated a truncated normal distribution for the non‐censored values (after an appropriate transformation of the data). Using Wei and Tanner's poor man's data augmentation algorithm, together with the technique of linear mixed effects modelling, useful reference‐curves could be produced. In contrast to the cumulative probabilities approach for ordinal data, our methodology allows the calculation of individual age‐ and gender‐standardized values, which puts us in a position to investigate numerous scientific questions. Copyright © 2004 John Wiley &amp; Sons, Ltd.</jats:p> Modelling neuromotor ratings with floor‐effects Statistics in Medicine
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title Modelling neuromotor ratings with floor‐effects
title_unstemmed Modelling neuromotor ratings with floor‐effects
title_full Modelling neuromotor ratings with floor‐effects
title_fullStr Modelling neuromotor ratings with floor‐effects
title_full_unstemmed Modelling neuromotor ratings with floor‐effects
title_short Modelling neuromotor ratings with floor‐effects
title_sort modelling neuromotor ratings with floor‐effects
topic Statistics and Probability
Epidemiology
url http://dx.doi.org/10.1002/sim.1914
publishDate 2004
physical 3641-3653
description <jats:title>Abstract</jats:title><jats:p>Associated movements (AMs) are a classical diagnostic tool to assess differences between normal children and children with some motor dysfunction. This paper presents a methodology to produce age‐ and gender‐dependent reference‐curves for AMs of normal children, for various tasks of a test battery. Data available consist of separate ratings of duration and extent of AMs, which are ordinal quantities with few levels. Other problems are severe age‐ and gender‐dependent floor‐effects (as well as some ceiling‐effects), leaving little information for analysis at older ages. To get a better scale, we combined the two ordinal ratings into one meaningful and quasi‐continuous quantity referred to as intensity of AMs. In order to solve problems due to floor‐effects, ceiling‐effects and discreteness, we assumed left‐ , right‐ and interval‐censored values, respectively. We considered a censored regression problem and postulated a truncated normal distribution for the non‐censored values (after an appropriate transformation of the data). Using Wei and Tanner's poor man's data augmentation algorithm, together with the technique of linear mixed effects modelling, useful reference‐curves could be produced. In contrast to the cumulative probabilities approach for ordinal data, our methodology allows the calculation of individual age‐ and gender‐standardized values, which puts us in a position to investigate numerous scientific questions. Copyright © 2004 John Wiley &amp; Sons, Ltd.</jats:p>
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author Gasser, Theo, Rousson, Valentin
author_facet Gasser, Theo, Rousson, Valentin, Gasser, Theo, Rousson, Valentin
author_sort gasser, theo
container_issue 23
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container_title Statistics in Medicine
container_volume 23
description <jats:title>Abstract</jats:title><jats:p>Associated movements (AMs) are a classical diagnostic tool to assess differences between normal children and children with some motor dysfunction. This paper presents a methodology to produce age‐ and gender‐dependent reference‐curves for AMs of normal children, for various tasks of a test battery. Data available consist of separate ratings of duration and extent of AMs, which are ordinal quantities with few levels. Other problems are severe age‐ and gender‐dependent floor‐effects (as well as some ceiling‐effects), leaving little information for analysis at older ages. To get a better scale, we combined the two ordinal ratings into one meaningful and quasi‐continuous quantity referred to as intensity of AMs. In order to solve problems due to floor‐effects, ceiling‐effects and discreteness, we assumed left‐ , right‐ and interval‐censored values, respectively. We considered a censored regression problem and postulated a truncated normal distribution for the non‐censored values (after an appropriate transformation of the data). Using Wei and Tanner's poor man's data augmentation algorithm, together with the technique of linear mixed effects modelling, useful reference‐curves could be produced. In contrast to the cumulative probabilities approach for ordinal data, our methodology allows the calculation of individual age‐ and gender‐standardized values, which puts us in a position to investigate numerous scientific questions. Copyright © 2004 John Wiley &amp; Sons, Ltd.</jats:p>
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spelling Gasser, Theo Rousson, Valentin 0277-6715 1097-0258 Wiley Statistics and Probability Epidemiology http://dx.doi.org/10.1002/sim.1914 <jats:title>Abstract</jats:title><jats:p>Associated movements (AMs) are a classical diagnostic tool to assess differences between normal children and children with some motor dysfunction. This paper presents a methodology to produce age‐ and gender‐dependent reference‐curves for AMs of normal children, for various tasks of a test battery. Data available consist of separate ratings of duration and extent of AMs, which are ordinal quantities with few levels. Other problems are severe age‐ and gender‐dependent floor‐effects (as well as some ceiling‐effects), leaving little information for analysis at older ages. To get a better scale, we combined the two ordinal ratings into one meaningful and quasi‐continuous quantity referred to as intensity of AMs. In order to solve problems due to floor‐effects, ceiling‐effects and discreteness, we assumed left‐ , right‐ and interval‐censored values, respectively. We considered a censored regression problem and postulated a truncated normal distribution for the non‐censored values (after an appropriate transformation of the data). Using Wei and Tanner's poor man's data augmentation algorithm, together with the technique of linear mixed effects modelling, useful reference‐curves could be produced. In contrast to the cumulative probabilities approach for ordinal data, our methodology allows the calculation of individual age‐ and gender‐standardized values, which puts us in a position to investigate numerous scientific questions. Copyright © 2004 John Wiley &amp; Sons, Ltd.</jats:p> Modelling neuromotor ratings with floor‐effects Statistics in Medicine
spellingShingle Gasser, Theo, Rousson, Valentin, Statistics in Medicine, Modelling neuromotor ratings with floor‐effects, Statistics and Probability, Epidemiology
title Modelling neuromotor ratings with floor‐effects
title_full Modelling neuromotor ratings with floor‐effects
title_fullStr Modelling neuromotor ratings with floor‐effects
title_full_unstemmed Modelling neuromotor ratings with floor‐effects
title_short Modelling neuromotor ratings with floor‐effects
title_sort modelling neuromotor ratings with floor‐effects
title_unstemmed Modelling neuromotor ratings with floor‐effects
topic Statistics and Probability, Epidemiology
url http://dx.doi.org/10.1002/sim.1914