Eintrag weiter verarbeiten
Treatment Options for Severe Obesity in the Pediatric Population: Current Limitations and Future Opportunities
Gespeichert in:
Zeitschriftentitel: | Obesity |
---|---|
Personen und Körperschaften: | , , |
In: | Obesity, 26, 2018, 6, S. 951-960 |
Format: | E-Article |
Sprache: | Englisch |
veröffentlicht: |
Wiley
|
Schlagwörter: |
author_facet |
Ryder, Justin R. Fox, Claudia K. Kelly, Aaron S. Ryder, Justin R. Fox, Claudia K. Kelly, Aaron S. |
---|---|
author |
Ryder, Justin R. Fox, Claudia K. Kelly, Aaron S. |
spellingShingle |
Ryder, Justin R. Fox, Claudia K. Kelly, Aaron S. Obesity Treatment Options for Severe Obesity in the Pediatric Population: Current Limitations and Future Opportunities Nutrition and Dietetics Endocrinology Endocrinology, Diabetes and Metabolism Medicine (miscellaneous) |
author_sort |
ryder, justin r. |
spelling |
Ryder, Justin R. Fox, Claudia K. Kelly, Aaron S. 1930-7381 1930-739X Wiley Nutrition and Dietetics Endocrinology Endocrinology, Diabetes and Metabolism Medicine (miscellaneous) http://dx.doi.org/10.1002/oby.22196 <jats:sec><jats:title>Objective</jats:title><jats:p>Severe obesity is the only obesity classification increasing in prevalence among children and adolescents. Treatment options that produce meaningful and sustained weight loss and comorbidity resolution are urgently needed.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>The purpose of this review is to provide a brief overview of the current treatment options for pediatric severe obesity and offer suggestions regarding future opportunities for accelerating the development and evaluation of innovative treatment strategies.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>At present, there are three treatment options for youth with severe obesity: lifestyle modification therapy, pharmacotherapy, and bariatric surgery. Lifestyle modification therapy can be useful for improving many chronic disease risk factors and comorbid conditions but often fails to achieve clinically meaningful and sustainable weight loss. Pharmacotherapy holds promise as an effective adjunctive treatment but remains in the primordial stages of development in the pediatric population. Bariatric surgery provides robust weight loss and risk factor/comorbidity improvements but is accompanied by higher risks and lower uptake compared to lifestyle modification therapy and pharmacotherapy. New areas worth pursuing include combination pharmacotherapy, device therapy, identification of predictors of response aimed at precision treatment, and interventions in the postbariatric surgical setting to improve long‐term outcomes.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Treating pediatric severe obesity effectively and safely is extremely challenging. Some progress has been made, but substantially more effort and innovation are needed in the future to combat this serious and ongoing medical and public health issue.</jats:p></jats:sec> Treatment Options for Severe Obesity in the Pediatric Population: Current Limitations and Future Opportunities Obesity |
doi_str_mv |
10.1002/oby.22196 |
facet_avail |
Online Free |
finc_class_facet |
Medizin |
format |
ElectronicArticle |
fullrecord |
blob:ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAwMi9vYnkuMjIxOTY |
id |
ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAwMi9vYnkuMjIxOTY |
institution |
DE-Ch1 DE-L229 DE-D275 DE-Bn3 DE-Brt1 DE-Zwi2 DE-D161 DE-Gla1 DE-Zi4 DE-15 DE-Rs1 DE-Pl11 DE-105 DE-14 |
imprint |
Wiley, 2018 |
imprint_str_mv |
Wiley, 2018 |
issn |
1930-7381 1930-739X |
issn_str_mv |
1930-7381 1930-739X |
language |
English |
mega_collection |
Wiley (CrossRef) |
match_str |
ryder2018treatmentoptionsforsevereobesityinthepediatricpopulationcurrentlimitationsandfutureopportunities |
publishDateSort |
2018 |
publisher |
Wiley |
recordtype |
ai |
record_format |
ai |
series |
Obesity |
source_id |
49 |
title |
Treatment Options for Severe Obesity in the Pediatric Population: Current Limitations and Future Opportunities |
title_unstemmed |
Treatment Options for Severe Obesity in the Pediatric Population: Current Limitations and Future Opportunities |
title_full |
Treatment Options for Severe Obesity in the Pediatric Population: Current Limitations and Future Opportunities |
title_fullStr |
Treatment Options for Severe Obesity in the Pediatric Population: Current Limitations and Future Opportunities |
title_full_unstemmed |
Treatment Options for Severe Obesity in the Pediatric Population: Current Limitations and Future Opportunities |
title_short |
Treatment Options for Severe Obesity in the Pediatric Population: Current Limitations and Future Opportunities |
title_sort |
treatment options for severe obesity in the pediatric population: current limitations and future opportunities |
topic |
Nutrition and Dietetics Endocrinology Endocrinology, Diabetes and Metabolism Medicine (miscellaneous) |
url |
http://dx.doi.org/10.1002/oby.22196 |
publishDate |
2018 |
physical |
951-960 |
description |
<jats:sec><jats:title>Objective</jats:title><jats:p>Severe obesity is the only obesity classification increasing in prevalence among children and adolescents. Treatment options that produce meaningful and sustained weight loss and comorbidity resolution are urgently needed.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>The purpose of this review is to provide a brief overview of the current treatment options for pediatric severe obesity and offer suggestions regarding future opportunities for accelerating the development and evaluation of innovative treatment strategies.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>At present, there are three treatment options for youth with severe obesity: lifestyle modification therapy, pharmacotherapy, and bariatric surgery. Lifestyle modification therapy can be useful for improving many chronic disease risk factors and comorbid conditions but often fails to achieve clinically meaningful and sustainable weight loss. Pharmacotherapy holds promise as an effective adjunctive treatment but remains in the primordial stages of development in the pediatric population. Bariatric surgery provides robust weight loss and risk factor/comorbidity improvements but is accompanied by higher risks and lower uptake compared to lifestyle modification therapy and pharmacotherapy. New areas worth pursuing include combination pharmacotherapy, device therapy, identification of predictors of response aimed at precision treatment, and interventions in the postbariatric surgical setting to improve long‐term outcomes.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Treating pediatric severe obesity effectively and safely is extremely challenging. Some progress has been made, but substantially more effort and innovation are needed in the future to combat this serious and ongoing medical and public health issue.</jats:p></jats:sec> |
container_issue |
6 |
container_start_page |
951 |
container_title |
Obesity |
container_volume |
26 |
format_de105 |
Article, E-Article |
format_de14 |
Article, E-Article |
format_de15 |
Article, E-Article |
format_de520 |
Article, E-Article |
format_de540 |
Article, E-Article |
format_dech1 |
Article, E-Article |
format_ded117 |
Article, E-Article |
format_degla1 |
E-Article |
format_del152 |
Buch |
format_del189 |
Article, E-Article |
format_dezi4 |
Article |
format_dezwi2 |
Article, E-Article |
format_finc |
Article, E-Article |
format_nrw |
Article, E-Article |
_version_ |
1792348679216037891 |
geogr_code |
not assigned |
last_indexed |
2024-03-01T18:15:00.914Z |
geogr_code_person |
not assigned |
openURL |
url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=Treatment+Options+for+Severe+Obesity+in+the+Pediatric+Population%3A+Current+Limitations+and+Future+Opportunities&rft.date=2018-06-01&genre=article&issn=1930-739X&volume=26&issue=6&spage=951&epage=960&pages=951-960&jtitle=Obesity&atitle=Treatment+Options+for+Severe+Obesity+in+the+Pediatric+Population%3A+Current+Limitations+and+Future+Opportunities&aulast=Kelly&aufirst=Aaron+S.&rft_id=info%3Adoi%2F10.1002%2Foby.22196&rft.language%5B0%5D=eng |
SOLR | |
_version_ | 1792348679216037891 |
author | Ryder, Justin R., Fox, Claudia K., Kelly, Aaron S. |
author_facet | Ryder, Justin R., Fox, Claudia K., Kelly, Aaron S., Ryder, Justin R., Fox, Claudia K., Kelly, Aaron S. |
author_sort | ryder, justin r. |
container_issue | 6 |
container_start_page | 951 |
container_title | Obesity |
container_volume | 26 |
description | <jats:sec><jats:title>Objective</jats:title><jats:p>Severe obesity is the only obesity classification increasing in prevalence among children and adolescents. Treatment options that produce meaningful and sustained weight loss and comorbidity resolution are urgently needed.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>The purpose of this review is to provide a brief overview of the current treatment options for pediatric severe obesity and offer suggestions regarding future opportunities for accelerating the development and evaluation of innovative treatment strategies.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>At present, there are three treatment options for youth with severe obesity: lifestyle modification therapy, pharmacotherapy, and bariatric surgery. Lifestyle modification therapy can be useful for improving many chronic disease risk factors and comorbid conditions but often fails to achieve clinically meaningful and sustainable weight loss. Pharmacotherapy holds promise as an effective adjunctive treatment but remains in the primordial stages of development in the pediatric population. Bariatric surgery provides robust weight loss and risk factor/comorbidity improvements but is accompanied by higher risks and lower uptake compared to lifestyle modification therapy and pharmacotherapy. New areas worth pursuing include combination pharmacotherapy, device therapy, identification of predictors of response aimed at precision treatment, and interventions in the postbariatric surgical setting to improve long‐term outcomes.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Treating pediatric severe obesity effectively and safely is extremely challenging. Some progress has been made, but substantially more effort and innovation are needed in the future to combat this serious and ongoing medical and public health issue.</jats:p></jats:sec> |
doi_str_mv | 10.1002/oby.22196 |
facet_avail | Online, Free |
finc_class_facet | Medizin |
format | ElectronicArticle |
format_de105 | Article, E-Article |
format_de14 | Article, E-Article |
format_de15 | Article, E-Article |
format_de520 | Article, E-Article |
format_de540 | Article, E-Article |
format_dech1 | Article, E-Article |
format_ded117 | Article, E-Article |
format_degla1 | E-Article |
format_del152 | Buch |
format_del189 | Article, E-Article |
format_dezi4 | Article |
format_dezwi2 | Article, E-Article |
format_finc | Article, E-Article |
format_nrw | Article, E-Article |
geogr_code | not assigned |
geogr_code_person | not assigned |
id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAwMi9vYnkuMjIxOTY |
imprint | Wiley, 2018 |
imprint_str_mv | Wiley, 2018 |
institution | DE-Ch1, DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-Zwi2, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Rs1, DE-Pl11, DE-105, DE-14 |
issn | 1930-7381, 1930-739X |
issn_str_mv | 1930-7381, 1930-739X |
language | English |
last_indexed | 2024-03-01T18:15:00.914Z |
match_str | ryder2018treatmentoptionsforsevereobesityinthepediatricpopulationcurrentlimitationsandfutureopportunities |
mega_collection | Wiley (CrossRef) |
physical | 951-960 |
publishDate | 2018 |
publishDateSort | 2018 |
publisher | Wiley |
record_format | ai |
recordtype | ai |
series | Obesity |
source_id | 49 |
spelling | Ryder, Justin R. Fox, Claudia K. Kelly, Aaron S. 1930-7381 1930-739X Wiley Nutrition and Dietetics Endocrinology Endocrinology, Diabetes and Metabolism Medicine (miscellaneous) http://dx.doi.org/10.1002/oby.22196 <jats:sec><jats:title>Objective</jats:title><jats:p>Severe obesity is the only obesity classification increasing in prevalence among children and adolescents. Treatment options that produce meaningful and sustained weight loss and comorbidity resolution are urgently needed.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>The purpose of this review is to provide a brief overview of the current treatment options for pediatric severe obesity and offer suggestions regarding future opportunities for accelerating the development and evaluation of innovative treatment strategies.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>At present, there are three treatment options for youth with severe obesity: lifestyle modification therapy, pharmacotherapy, and bariatric surgery. Lifestyle modification therapy can be useful for improving many chronic disease risk factors and comorbid conditions but often fails to achieve clinically meaningful and sustainable weight loss. Pharmacotherapy holds promise as an effective adjunctive treatment but remains in the primordial stages of development in the pediatric population. Bariatric surgery provides robust weight loss and risk factor/comorbidity improvements but is accompanied by higher risks and lower uptake compared to lifestyle modification therapy and pharmacotherapy. New areas worth pursuing include combination pharmacotherapy, device therapy, identification of predictors of response aimed at precision treatment, and interventions in the postbariatric surgical setting to improve long‐term outcomes.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Treating pediatric severe obesity effectively and safely is extremely challenging. Some progress has been made, but substantially more effort and innovation are needed in the future to combat this serious and ongoing medical and public health issue.</jats:p></jats:sec> Treatment Options for Severe Obesity in the Pediatric Population: Current Limitations and Future Opportunities Obesity |
spellingShingle | Ryder, Justin R., Fox, Claudia K., Kelly, Aaron S., Obesity, Treatment Options for Severe Obesity in the Pediatric Population: Current Limitations and Future Opportunities, Nutrition and Dietetics, Endocrinology, Endocrinology, Diabetes and Metabolism, Medicine (miscellaneous) |
title | Treatment Options for Severe Obesity in the Pediatric Population: Current Limitations and Future Opportunities |
title_full | Treatment Options for Severe Obesity in the Pediatric Population: Current Limitations and Future Opportunities |
title_fullStr | Treatment Options for Severe Obesity in the Pediatric Population: Current Limitations and Future Opportunities |
title_full_unstemmed | Treatment Options for Severe Obesity in the Pediatric Population: Current Limitations and Future Opportunities |
title_short | Treatment Options for Severe Obesity in the Pediatric Population: Current Limitations and Future Opportunities |
title_sort | treatment options for severe obesity in the pediatric population: current limitations and future opportunities |
title_unstemmed | Treatment Options for Severe Obesity in the Pediatric Population: Current Limitations and Future Opportunities |
topic | Nutrition and Dietetics, Endocrinology, Endocrinology, Diabetes and Metabolism, Medicine (miscellaneous) |
url | http://dx.doi.org/10.1002/oby.22196 |