Eintrag weiter verarbeiten
Mechanisms of weight maintenance under high‐ and low‐protein, low‐glycaemic index diets
Gespeichert in:
| Zeitschriftentitel: | Molecular Nutrition & Food Research |
|---|---|
| Personen und Körperschaften: | , , , , , , , , , |
| In: | Molecular Nutrition & Food Research, 55, 2011, 11, S. 1603-1612 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Wiley
|
| Schlagwörter: |
| author_facet |
Rubio‐Aliaga, Isabel Marvin‐Guy, Laure F. Wang, Ping Wagniere, Sandrine Mansourian, Robert Fuerholz, Andreas Saris, Wim H. M. Astrup, Arne Mariman, Edwin C. M. Kussmann, Martin Rubio‐Aliaga, Isabel Marvin‐Guy, Laure F. Wang, Ping Wagniere, Sandrine Mansourian, Robert Fuerholz, Andreas Saris, Wim H. M. Astrup, Arne Mariman, Edwin C. M. Kussmann, Martin |
|---|---|
| author |
Rubio‐Aliaga, Isabel Marvin‐Guy, Laure F. Wang, Ping Wagniere, Sandrine Mansourian, Robert Fuerholz, Andreas Saris, Wim H. M. Astrup, Arne Mariman, Edwin C. M. Kussmann, Martin |
| spellingShingle |
Rubio‐Aliaga, Isabel Marvin‐Guy, Laure F. Wang, Ping Wagniere, Sandrine Mansourian, Robert Fuerholz, Andreas Saris, Wim H. M. Astrup, Arne Mariman, Edwin C. M. Kussmann, Martin Molecular Nutrition & Food Research Mechanisms of weight maintenance under high‐ and low‐protein, low‐glycaemic index diets Food Science Biotechnology |
| author_sort |
rubio‐aliaga, isabel |
| spelling |
Rubio‐Aliaga, Isabel Marvin‐Guy, Laure F. Wang, Ping Wagniere, Sandrine Mansourian, Robert Fuerholz, Andreas Saris, Wim H. M. Astrup, Arne Mariman, Edwin C. M. Kussmann, Martin 1613-4125 1613-4133 Wiley Food Science Biotechnology http://dx.doi.org/10.1002/mnfr.201100081 <jats:title>Abstract</jats:title><jats:p><jats:bold>Scope:</jats:bold> Weight maintenance after intended weight loss is a challenge in an obesogenic environment. In a large multicentre dietary intervention study (DiOGenes), it has recently been demonstrated that a high‐protein/low‐glycaemic index (HP/LGI) diet was slightly more efficient in maintaining weight loss than low‐protein/LGI or high‐GI (LP/LGI or HGI) diets. Here, we use a proteomic approach to assess the molecular mechanisms behind this positive effect.</jats:p><jats:p><jats:bold>Methods and results:</jats:bold> A subset of the most successful (weight loser, <jats:italic>n</jats:italic>=12) and unsuccessful (weight re‐gainer, <jats:italic>n</jats:italic>=12) individuals consuming the LGI diets with either high‐ or low‐protein content (HP or LP/LGI), following an initial calorie deficit run‐in weight loss phase, were analyzed at the plasma protein level. Proteomic analysis revealed 18 proteins regulated after 6 months of the dietary weight maintenance phase. Furthermore, 12 proteins were significantly regulated as a function of success rate under an HP diet, arising as candidate biomarkers of mechanisms of successful weight maintenance under an HP/LGI diet. Pregnancy‐zone protein (PZP) and protein S (PROS1) were revealed as novel biomarkers of weight maintenance showing opposite effects.</jats:p><jats:p><jats:bold>Conclusion:</jats:bold> Semantic network analysis of the 12 regulated proteins revealed that under an HP/LGI an anti‐atherogenic effect and alterations of fat metabolism were associated with the success of maintaining the initial weight loss.</jats:p> Mechanisms of weight maintenance under high‐ and low‐protein, low‐glycaemic index diets Molecular Nutrition & Food Research |
| doi_str_mv |
10.1002/mnfr.201100081 |
| facet_avail |
Online |
| finc_class_facet |
Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft Biologie Technik |
| format |
ElectronicArticle |
| fullrecord |
blob:ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAwMi9tbmZyLjIwMTEwMDA4MQ |
| id |
ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAwMi9tbmZyLjIwMTEwMDA4MQ |
| institution |
DE-L229 DE-D275 DE-Bn3 DE-Brt1 DE-D161 DE-Gla1 DE-Zi4 DE-15 DE-Pl11 DE-Rs1 DE-105 DE-14 DE-Ch1 |
| imprint |
Wiley, 2011 |
| imprint_str_mv |
Wiley, 2011 |
| issn |
1613-4125 1613-4133 |
| issn_str_mv |
1613-4125 1613-4133 |
| language |
English |
| mega_collection |
Wiley (CrossRef) |
| match_str |
rubioaliaga2011mechanismsofweightmaintenanceunderhighandlowproteinlowglycaemicindexdiets |
| publishDateSort |
2011 |
| publisher |
Wiley |
| recordtype |
ai |
| record_format |
ai |
| series |
Molecular Nutrition & Food Research |
| source_id |
49 |
| title |
Mechanisms of weight maintenance under high‐ and low‐protein, low‐glycaemic index diets |
| title_unstemmed |
Mechanisms of weight maintenance under high‐ and low‐protein, low‐glycaemic index diets |
| title_full |
Mechanisms of weight maintenance under high‐ and low‐protein, low‐glycaemic index diets |
| title_fullStr |
Mechanisms of weight maintenance under high‐ and low‐protein, low‐glycaemic index diets |
| title_full_unstemmed |
Mechanisms of weight maintenance under high‐ and low‐protein, low‐glycaemic index diets |
| title_short |
Mechanisms of weight maintenance under high‐ and low‐protein, low‐glycaemic index diets |
| title_sort |
mechanisms of weight maintenance under high‐ and low‐protein, low‐glycaemic index diets |
| topic |
Food Science Biotechnology |
| url |
http://dx.doi.org/10.1002/mnfr.201100081 |
| publishDate |
2011 |
| physical |
1603-1612 |
| description |
<jats:title>Abstract</jats:title><jats:p><jats:bold>Scope:</jats:bold> Weight maintenance after intended weight loss is a challenge in an obesogenic environment. In a large multicentre dietary intervention study (DiOGenes), it has recently been demonstrated that a high‐protein/low‐glycaemic index (HP/LGI) diet was slightly more efficient in maintaining weight loss than low‐protein/LGI or high‐GI (LP/LGI or HGI) diets. Here, we use a proteomic approach to assess the molecular mechanisms behind this positive effect.</jats:p><jats:p><jats:bold>Methods and results:</jats:bold> A subset of the most successful (weight loser, <jats:italic>n</jats:italic>=12) and unsuccessful (weight re‐gainer, <jats:italic>n</jats:italic>=12) individuals consuming the LGI diets with either high‐ or low‐protein content (HP or LP/LGI), following an initial calorie deficit run‐in weight loss phase, were analyzed at the plasma protein level. Proteomic analysis revealed 18 proteins regulated after 6 months of the dietary weight maintenance phase. Furthermore, 12 proteins were significantly regulated as a function of success rate under an HP diet, arising as candidate biomarkers of mechanisms of successful weight maintenance under an HP/LGI diet. Pregnancy‐zone protein (PZP) and protein S (PROS1) were revealed as novel biomarkers of weight maintenance showing opposite effects.</jats:p><jats:p><jats:bold>Conclusion:</jats:bold> Semantic network analysis of the 12 regulated proteins revealed that under an HP/LGI an anti‐atherogenic effect and alterations of fat metabolism were associated with the success of maintaining the initial weight loss.</jats:p> |
| container_issue |
11 |
| container_start_page |
1603 |
| container_title |
Molecular Nutrition & Food Research |
| container_volume |
55 |
| format_de105 |
Article, E-Article |
| format_de14 |
Article, E-Article |
| format_de15 |
Article, E-Article |
| format_de520 |
Article, E-Article |
| format_de540 |
Article, E-Article |
| format_dech1 |
Article, E-Article |
| format_ded117 |
Article, E-Article |
| format_degla1 |
E-Article |
| format_del152 |
Buch |
| format_del189 |
Article, E-Article |
| format_dezi4 |
Article |
| format_dezwi2 |
Article, E-Article |
| format_finc |
Article, E-Article |
| format_nrw |
Article, E-Article |
| _version_ |
1792335315404324865 |
| geogr_code |
not assigned |
| last_indexed |
2024-03-01T14:42:35.918Z |
| geogr_code_person |
not assigned |
| openURL |
url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=Mechanisms+of+weight+maintenance+under+high%E2%80%90+and+low%E2%80%90protein%2C+low%E2%80%90glycaemic+index+diets&rft.date=2011-11-01&genre=article&issn=1613-4133&volume=55&issue=11&spage=1603&epage=1612&pages=1603-1612&jtitle=Molecular+Nutrition+%26+Food+Research&atitle=Mechanisms+of+weight+maintenance+under+high%E2%80%90+and+low%E2%80%90protein%2C+low%E2%80%90glycaemic+index+diets&aulast=Kussmann&aufirst=Martin&rft_id=info%3Adoi%2F10.1002%2Fmnfr.201100081&rft.language%5B0%5D=eng |
| SOLR | |
| _version_ | 1792335315404324865 |
| author | Rubio‐Aliaga, Isabel, Marvin‐Guy, Laure F., Wang, Ping, Wagniere, Sandrine, Mansourian, Robert, Fuerholz, Andreas, Saris, Wim H. M., Astrup, Arne, Mariman, Edwin C. M., Kussmann, Martin |
| author_facet | Rubio‐Aliaga, Isabel, Marvin‐Guy, Laure F., Wang, Ping, Wagniere, Sandrine, Mansourian, Robert, Fuerholz, Andreas, Saris, Wim H. M., Astrup, Arne, Mariman, Edwin C. M., Kussmann, Martin, Rubio‐Aliaga, Isabel, Marvin‐Guy, Laure F., Wang, Ping, Wagniere, Sandrine, Mansourian, Robert, Fuerholz, Andreas, Saris, Wim H. M., Astrup, Arne, Mariman, Edwin C. M., Kussmann, Martin |
| author_sort | rubio‐aliaga, isabel |
| container_issue | 11 |
| container_start_page | 1603 |
| container_title | Molecular Nutrition & Food Research |
| container_volume | 55 |
| description | <jats:title>Abstract</jats:title><jats:p><jats:bold>Scope:</jats:bold> Weight maintenance after intended weight loss is a challenge in an obesogenic environment. In a large multicentre dietary intervention study (DiOGenes), it has recently been demonstrated that a high‐protein/low‐glycaemic index (HP/LGI) diet was slightly more efficient in maintaining weight loss than low‐protein/LGI or high‐GI (LP/LGI or HGI) diets. Here, we use a proteomic approach to assess the molecular mechanisms behind this positive effect.</jats:p><jats:p><jats:bold>Methods and results:</jats:bold> A subset of the most successful (weight loser, <jats:italic>n</jats:italic>=12) and unsuccessful (weight re‐gainer, <jats:italic>n</jats:italic>=12) individuals consuming the LGI diets with either high‐ or low‐protein content (HP or LP/LGI), following an initial calorie deficit run‐in weight loss phase, were analyzed at the plasma protein level. Proteomic analysis revealed 18 proteins regulated after 6 months of the dietary weight maintenance phase. Furthermore, 12 proteins were significantly regulated as a function of success rate under an HP diet, arising as candidate biomarkers of mechanisms of successful weight maintenance under an HP/LGI diet. Pregnancy‐zone protein (PZP) and protein S (PROS1) were revealed as novel biomarkers of weight maintenance showing opposite effects.</jats:p><jats:p><jats:bold>Conclusion:</jats:bold> Semantic network analysis of the 12 regulated proteins revealed that under an HP/LGI an anti‐atherogenic effect and alterations of fat metabolism were associated with the success of maintaining the initial weight loss.</jats:p> |
| doi_str_mv | 10.1002/mnfr.201100081 |
| facet_avail | Online |
| finc_class_facet | Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft, Biologie, Technik |
| format | ElectronicArticle |
| format_de105 | Article, E-Article |
| format_de14 | Article, E-Article |
| format_de15 | Article, E-Article |
| format_de520 | Article, E-Article |
| format_de540 | Article, E-Article |
| format_dech1 | Article, E-Article |
| format_ded117 | Article, E-Article |
| format_degla1 | E-Article |
| format_del152 | Buch |
| format_del189 | Article, E-Article |
| format_dezi4 | Article |
| format_dezwi2 | Article, E-Article |
| format_finc | Article, E-Article |
| format_nrw | Article, E-Article |
| geogr_code | not assigned |
| geogr_code_person | not assigned |
| id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAwMi9tbmZyLjIwMTEwMDA4MQ |
| imprint | Wiley, 2011 |
| imprint_str_mv | Wiley, 2011 |
| institution | DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1 |
| issn | 1613-4125, 1613-4133 |
| issn_str_mv | 1613-4125, 1613-4133 |
| language | English |
| last_indexed | 2024-03-01T14:42:35.918Z |
| match_str | rubioaliaga2011mechanismsofweightmaintenanceunderhighandlowproteinlowglycaemicindexdiets |
| mega_collection | Wiley (CrossRef) |
| physical | 1603-1612 |
| publishDate | 2011 |
| publishDateSort | 2011 |
| publisher | Wiley |
| record_format | ai |
| recordtype | ai |
| series | Molecular Nutrition & Food Research |
| source_id | 49 |
| spelling | Rubio‐Aliaga, Isabel Marvin‐Guy, Laure F. Wang, Ping Wagniere, Sandrine Mansourian, Robert Fuerholz, Andreas Saris, Wim H. M. Astrup, Arne Mariman, Edwin C. M. Kussmann, Martin 1613-4125 1613-4133 Wiley Food Science Biotechnology http://dx.doi.org/10.1002/mnfr.201100081 <jats:title>Abstract</jats:title><jats:p><jats:bold>Scope:</jats:bold> Weight maintenance after intended weight loss is a challenge in an obesogenic environment. In a large multicentre dietary intervention study (DiOGenes), it has recently been demonstrated that a high‐protein/low‐glycaemic index (HP/LGI) diet was slightly more efficient in maintaining weight loss than low‐protein/LGI or high‐GI (LP/LGI or HGI) diets. Here, we use a proteomic approach to assess the molecular mechanisms behind this positive effect.</jats:p><jats:p><jats:bold>Methods and results:</jats:bold> A subset of the most successful (weight loser, <jats:italic>n</jats:italic>=12) and unsuccessful (weight re‐gainer, <jats:italic>n</jats:italic>=12) individuals consuming the LGI diets with either high‐ or low‐protein content (HP or LP/LGI), following an initial calorie deficit run‐in weight loss phase, were analyzed at the plasma protein level. Proteomic analysis revealed 18 proteins regulated after 6 months of the dietary weight maintenance phase. Furthermore, 12 proteins were significantly regulated as a function of success rate under an HP diet, arising as candidate biomarkers of mechanisms of successful weight maintenance under an HP/LGI diet. Pregnancy‐zone protein (PZP) and protein S (PROS1) were revealed as novel biomarkers of weight maintenance showing opposite effects.</jats:p><jats:p><jats:bold>Conclusion:</jats:bold> Semantic network analysis of the 12 regulated proteins revealed that under an HP/LGI an anti‐atherogenic effect and alterations of fat metabolism were associated with the success of maintaining the initial weight loss.</jats:p> Mechanisms of weight maintenance under high‐ and low‐protein, low‐glycaemic index diets Molecular Nutrition & Food Research |
| spellingShingle | Rubio‐Aliaga, Isabel, Marvin‐Guy, Laure F., Wang, Ping, Wagniere, Sandrine, Mansourian, Robert, Fuerholz, Andreas, Saris, Wim H. M., Astrup, Arne, Mariman, Edwin C. M., Kussmann, Martin, Molecular Nutrition & Food Research, Mechanisms of weight maintenance under high‐ and low‐protein, low‐glycaemic index diets, Food Science, Biotechnology |
| title | Mechanisms of weight maintenance under high‐ and low‐protein, low‐glycaemic index diets |
| title_full | Mechanisms of weight maintenance under high‐ and low‐protein, low‐glycaemic index diets |
| title_fullStr | Mechanisms of weight maintenance under high‐ and low‐protein, low‐glycaemic index diets |
| title_full_unstemmed | Mechanisms of weight maintenance under high‐ and low‐protein, low‐glycaemic index diets |
| title_short | Mechanisms of weight maintenance under high‐ and low‐protein, low‐glycaemic index diets |
| title_sort | mechanisms of weight maintenance under high‐ and low‐protein, low‐glycaemic index diets |
| title_unstemmed | Mechanisms of weight maintenance under high‐ and low‐protein, low‐glycaemic index diets |
| topic | Food Science, Biotechnology |
| url | http://dx.doi.org/10.1002/mnfr.201100081 |