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Comparison of quantitative coronary angiography and first‐pass perfusion magnetic resonance imaging for the detection of an impaired coronary perfusion in nonsevere coronary stenos...
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| Zeitschriftentitel: | Journal of Magnetic Resonance Imaging |
|---|---|
| Personen und Körperschaften: | , , , , , , , , , |
| In: | Journal of Magnetic Resonance Imaging, 27, 2008, 5, S. 1005-1011 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Wiley
|
| Schlagwörter: |
| author_facet |
Barmeyer, Achim A. Stork, Alexander Muellerleile, Kai Schofer, Anne K. Tiburtius, Claudia Koester, Ralf Heitzer, Thomas Adam, Gerhard Meinertz, Thomas Lund, Gunnar K. Barmeyer, Achim A. Stork, Alexander Muellerleile, Kai Schofer, Anne K. Tiburtius, Claudia Koester, Ralf Heitzer, Thomas Adam, Gerhard Meinertz, Thomas Lund, Gunnar K. |
|---|---|
| author |
Barmeyer, Achim A. Stork, Alexander Muellerleile, Kai Schofer, Anne K. Tiburtius, Claudia Koester, Ralf Heitzer, Thomas Adam, Gerhard Meinertz, Thomas Lund, Gunnar K. |
| spellingShingle |
Barmeyer, Achim A. Stork, Alexander Muellerleile, Kai Schofer, Anne K. Tiburtius, Claudia Koester, Ralf Heitzer, Thomas Adam, Gerhard Meinertz, Thomas Lund, Gunnar K. Journal of Magnetic Resonance Imaging Comparison of quantitative coronary angiography and first‐pass perfusion magnetic resonance imaging for the detection of an impaired coronary perfusion in nonsevere coronary stenosis Radiology, Nuclear Medicine and imaging |
| author_sort |
barmeyer, achim a. |
| spelling |
Barmeyer, Achim A. Stork, Alexander Muellerleile, Kai Schofer, Anne K. Tiburtius, Claudia Koester, Ralf Heitzer, Thomas Adam, Gerhard Meinertz, Thomas Lund, Gunnar K. 1053-1807 1522-2586 Wiley Radiology, Nuclear Medicine and imaging http://dx.doi.org/10.1002/jmri.21341 <jats:title>Abstract</jats:title><jats:sec><jats:title>Purpose</jats:title><jats:p>To compare quantitative coronary angiography (QCA) and first‐pass perfusion magnetic resonance imaging (FPP‐MRI) in symptomatic patients with nonsevere coronary stenosis to detect a reduced coronary flow velocity reserve (CFVR).</jats:p></jats:sec><jats:sec><jats:title>Materials and Methods</jats:title><jats:p>In 35 patients, FPP‐MRI and CFVR measurements were performed in 40 coronary arteries with a diameter stenosis (DS) <70% by QCA. From FPP‐MRI a myocardial perfusion reserve index (MPRI) was calculated. CFVR was calculated as the ratio of the average peak flow velocity during infusion of adenosine and at rest and was considered reduced if <2. Diagnostic performance of MPRI and DS to detect a reduced CFVR was compared by receiver operating characteristic (ROC) curve analysis.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>CFVR was reduced in 16 coronary arteries (40%). Mean DS did not differ in coronary arteries with a reduced CFVR (41.0% ± 13.3) and a normal CFVR (36.5% ± 12.3; <jats:italic>P</jats:italic> = 0.281). Mean MPRI was lower in coronary arteries with a reduced CFVR (1.12 ± 0.12) compared to a normal CFVR (1.33 ± 0.2; <jats:italic>P</jats:italic> < 0.001). Sensitivity, specificity, and area under the ROC curve (AUC) were higher for MPRI (81%, 79%, 0.84) than for DS (56%, 58%, 0.60).</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>FPP‐MRI detects impaired CFVR in symptomatic patients with nonsevere coronary stenosis more accurately than QCA and can identify patients with symptomatic ischemia. J. Magn. Reson. Imaging 2008;27:1005–1011. © 2008 Wiley‐Liss, Inc.</jats:p></jats:sec> Comparison of quantitative coronary angiography and first‐pass perfusion magnetic resonance imaging for the detection of an impaired coronary perfusion in nonsevere coronary stenosis Journal of Magnetic Resonance Imaging |
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Journal of Magnetic Resonance Imaging |
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| title |
Comparison of quantitative coronary angiography and first‐pass perfusion magnetic resonance imaging for the detection of an impaired coronary perfusion in nonsevere coronary stenosis |
| title_unstemmed |
Comparison of quantitative coronary angiography and first‐pass perfusion magnetic resonance imaging for the detection of an impaired coronary perfusion in nonsevere coronary stenosis |
| title_full |
Comparison of quantitative coronary angiography and first‐pass perfusion magnetic resonance imaging for the detection of an impaired coronary perfusion in nonsevere coronary stenosis |
| title_fullStr |
Comparison of quantitative coronary angiography and first‐pass perfusion magnetic resonance imaging for the detection of an impaired coronary perfusion in nonsevere coronary stenosis |
| title_full_unstemmed |
Comparison of quantitative coronary angiography and first‐pass perfusion magnetic resonance imaging for the detection of an impaired coronary perfusion in nonsevere coronary stenosis |
| title_short |
Comparison of quantitative coronary angiography and first‐pass perfusion magnetic resonance imaging for the detection of an impaired coronary perfusion in nonsevere coronary stenosis |
| title_sort |
comparison of quantitative coronary angiography and first‐pass perfusion magnetic resonance imaging for the detection of an impaired coronary perfusion in nonsevere coronary stenosis |
| topic |
Radiology, Nuclear Medicine and imaging |
| url |
http://dx.doi.org/10.1002/jmri.21341 |
| publishDate |
2008 |
| physical |
1005-1011 |
| description |
<jats:title>Abstract</jats:title><jats:sec><jats:title>Purpose</jats:title><jats:p>To compare quantitative coronary angiography (QCA) and first‐pass perfusion magnetic resonance imaging (FPP‐MRI) in symptomatic patients with nonsevere coronary stenosis to detect a reduced coronary flow velocity reserve (CFVR).</jats:p></jats:sec><jats:sec><jats:title>Materials and Methods</jats:title><jats:p>In 35 patients, FPP‐MRI and CFVR measurements were performed in 40 coronary arteries with a diameter stenosis (DS) <70% by QCA. From FPP‐MRI a myocardial perfusion reserve index (MPRI) was calculated. CFVR was calculated as the ratio of the average peak flow velocity during infusion of adenosine and at rest and was considered reduced if <2. Diagnostic performance of MPRI and DS to detect a reduced CFVR was compared by receiver operating characteristic (ROC) curve analysis.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>CFVR was reduced in 16 coronary arteries (40%). Mean DS did not differ in coronary arteries with a reduced CFVR (41.0% ± 13.3) and a normal CFVR (36.5% ± 12.3; <jats:italic>P</jats:italic> = 0.281). Mean MPRI was lower in coronary arteries with a reduced CFVR (1.12 ± 0.12) compared to a normal CFVR (1.33 ± 0.2; <jats:italic>P</jats:italic> < 0.001). Sensitivity, specificity, and area under the ROC curve (AUC) were higher for MPRI (81%, 79%, 0.84) than for DS (56%, 58%, 0.60).</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>FPP‐MRI detects impaired CFVR in symptomatic patients with nonsevere coronary stenosis more accurately than QCA and can identify patients with symptomatic ischemia. J. Magn. Reson. Imaging 2008;27:1005–1011. © 2008 Wiley‐Liss, Inc.</jats:p></jats:sec> |
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| author | Barmeyer, Achim A., Stork, Alexander, Muellerleile, Kai, Schofer, Anne K., Tiburtius, Claudia, Koester, Ralf, Heitzer, Thomas, Adam, Gerhard, Meinertz, Thomas, Lund, Gunnar K. |
| author_facet | Barmeyer, Achim A., Stork, Alexander, Muellerleile, Kai, Schofer, Anne K., Tiburtius, Claudia, Koester, Ralf, Heitzer, Thomas, Adam, Gerhard, Meinertz, Thomas, Lund, Gunnar K., Barmeyer, Achim A., Stork, Alexander, Muellerleile, Kai, Schofer, Anne K., Tiburtius, Claudia, Koester, Ralf, Heitzer, Thomas, Adam, Gerhard, Meinertz, Thomas, Lund, Gunnar K. |
| author_sort | barmeyer, achim a. |
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| description | <jats:title>Abstract</jats:title><jats:sec><jats:title>Purpose</jats:title><jats:p>To compare quantitative coronary angiography (QCA) and first‐pass perfusion magnetic resonance imaging (FPP‐MRI) in symptomatic patients with nonsevere coronary stenosis to detect a reduced coronary flow velocity reserve (CFVR).</jats:p></jats:sec><jats:sec><jats:title>Materials and Methods</jats:title><jats:p>In 35 patients, FPP‐MRI and CFVR measurements were performed in 40 coronary arteries with a diameter stenosis (DS) <70% by QCA. From FPP‐MRI a myocardial perfusion reserve index (MPRI) was calculated. CFVR was calculated as the ratio of the average peak flow velocity during infusion of adenosine and at rest and was considered reduced if <2. Diagnostic performance of MPRI and DS to detect a reduced CFVR was compared by receiver operating characteristic (ROC) curve analysis.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>CFVR was reduced in 16 coronary arteries (40%). Mean DS did not differ in coronary arteries with a reduced CFVR (41.0% ± 13.3) and a normal CFVR (36.5% ± 12.3; <jats:italic>P</jats:italic> = 0.281). Mean MPRI was lower in coronary arteries with a reduced CFVR (1.12 ± 0.12) compared to a normal CFVR (1.33 ± 0.2; <jats:italic>P</jats:italic> < 0.001). Sensitivity, specificity, and area under the ROC curve (AUC) were higher for MPRI (81%, 79%, 0.84) than for DS (56%, 58%, 0.60).</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>FPP‐MRI detects impaired CFVR in symptomatic patients with nonsevere coronary stenosis more accurately than QCA and can identify patients with symptomatic ischemia. J. Magn. Reson. Imaging 2008;27:1005–1011. © 2008 Wiley‐Liss, Inc.</jats:p></jats:sec> |
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| imprint | Wiley, 2008 |
| imprint_str_mv | Wiley, 2008 |
| institution | DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1, DE-L229, DE-D275, DE-Bn3, DE-Brt1 |
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| spelling | Barmeyer, Achim A. Stork, Alexander Muellerleile, Kai Schofer, Anne K. Tiburtius, Claudia Koester, Ralf Heitzer, Thomas Adam, Gerhard Meinertz, Thomas Lund, Gunnar K. 1053-1807 1522-2586 Wiley Radiology, Nuclear Medicine and imaging http://dx.doi.org/10.1002/jmri.21341 <jats:title>Abstract</jats:title><jats:sec><jats:title>Purpose</jats:title><jats:p>To compare quantitative coronary angiography (QCA) and first‐pass perfusion magnetic resonance imaging (FPP‐MRI) in symptomatic patients with nonsevere coronary stenosis to detect a reduced coronary flow velocity reserve (CFVR).</jats:p></jats:sec><jats:sec><jats:title>Materials and Methods</jats:title><jats:p>In 35 patients, FPP‐MRI and CFVR measurements were performed in 40 coronary arteries with a diameter stenosis (DS) <70% by QCA. From FPP‐MRI a myocardial perfusion reserve index (MPRI) was calculated. CFVR was calculated as the ratio of the average peak flow velocity during infusion of adenosine and at rest and was considered reduced if <2. Diagnostic performance of MPRI and DS to detect a reduced CFVR was compared by receiver operating characteristic (ROC) curve analysis.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>CFVR was reduced in 16 coronary arteries (40%). Mean DS did not differ in coronary arteries with a reduced CFVR (41.0% ± 13.3) and a normal CFVR (36.5% ± 12.3; <jats:italic>P</jats:italic> = 0.281). Mean MPRI was lower in coronary arteries with a reduced CFVR (1.12 ± 0.12) compared to a normal CFVR (1.33 ± 0.2; <jats:italic>P</jats:italic> < 0.001). Sensitivity, specificity, and area under the ROC curve (AUC) were higher for MPRI (81%, 79%, 0.84) than for DS (56%, 58%, 0.60).</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>FPP‐MRI detects impaired CFVR in symptomatic patients with nonsevere coronary stenosis more accurately than QCA and can identify patients with symptomatic ischemia. J. Magn. Reson. Imaging 2008;27:1005–1011. © 2008 Wiley‐Liss, Inc.</jats:p></jats:sec> Comparison of quantitative coronary angiography and first‐pass perfusion magnetic resonance imaging for the detection of an impaired coronary perfusion in nonsevere coronary stenosis Journal of Magnetic Resonance Imaging |
| spellingShingle | Barmeyer, Achim A., Stork, Alexander, Muellerleile, Kai, Schofer, Anne K., Tiburtius, Claudia, Koester, Ralf, Heitzer, Thomas, Adam, Gerhard, Meinertz, Thomas, Lund, Gunnar K., Journal of Magnetic Resonance Imaging, Comparison of quantitative coronary angiography and first‐pass perfusion magnetic resonance imaging for the detection of an impaired coronary perfusion in nonsevere coronary stenosis, Radiology, Nuclear Medicine and imaging |
| title | Comparison of quantitative coronary angiography and first‐pass perfusion magnetic resonance imaging for the detection of an impaired coronary perfusion in nonsevere coronary stenosis |
| title_full | Comparison of quantitative coronary angiography and first‐pass perfusion magnetic resonance imaging for the detection of an impaired coronary perfusion in nonsevere coronary stenosis |
| title_fullStr | Comparison of quantitative coronary angiography and first‐pass perfusion magnetic resonance imaging for the detection of an impaired coronary perfusion in nonsevere coronary stenosis |
| title_full_unstemmed | Comparison of quantitative coronary angiography and first‐pass perfusion magnetic resonance imaging for the detection of an impaired coronary perfusion in nonsevere coronary stenosis |
| title_short | Comparison of quantitative coronary angiography and first‐pass perfusion magnetic resonance imaging for the detection of an impaired coronary perfusion in nonsevere coronary stenosis |
| title_sort | comparison of quantitative coronary angiography and first‐pass perfusion magnetic resonance imaging for the detection of an impaired coronary perfusion in nonsevere coronary stenosis |
| title_unstemmed | Comparison of quantitative coronary angiography and first‐pass perfusion magnetic resonance imaging for the detection of an impaired coronary perfusion in nonsevere coronary stenosis |
| topic | Radiology, Nuclear Medicine and imaging |
| url | http://dx.doi.org/10.1002/jmri.21341 |