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Synthesis of [2‐14C(U)tyrosine]arginine vasotocin with high specific radio and biological activities
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Zeitschriftentitel: | Journal of Labelled Compounds and Radiopharmaceuticals |
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Personen und Körperschaften: | , |
In: | Journal of Labelled Compounds and Radiopharmaceuticals, 14, 1978, 6, S. 881-886 |
Format: | E-Article |
Sprache: | Englisch |
veröffentlicht: |
Wiley
|
Schlagwörter: |
author_facet |
Stahl, Glenn L. Walter, Roderich Stahl, Glenn L. Walter, Roderich |
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author |
Stahl, Glenn L. Walter, Roderich |
spellingShingle |
Stahl, Glenn L. Walter, Roderich Journal of Labelled Compounds and Radiopharmaceuticals Synthesis of [2‐14C(U)tyrosine]arginine vasotocin with high specific radio and biological activities Organic Chemistry Spectroscopy Drug Discovery Radiology, Nuclear Medicine and imaging Biochemistry Analytical Chemistry |
author_sort |
stahl, glenn l. |
spelling |
Stahl, Glenn L. Walter, Roderich 0362-4803 1099-1344 Wiley Organic Chemistry Spectroscopy Drug Discovery Radiology, Nuclear Medicine and imaging Biochemistry Analytical Chemistry http://dx.doi.org/10.1002/jlcr.2580140612 <jats:title>Abstract</jats:title><jats:p>The synthesis of [2‐<jats:sup>14</jats:sup>C(U)tyrosine]arginine vasotocin at a specific activity of 102 mCi/mMole was performed using the solid‐phase approach of Merrifield for peptide synthesis. Following purification by gel filtrations the labeled hormone was recovered at an average yield of 40% with an avian vasodepressor activity of 408 ± 24 U/mg.</jats:p> Synthesis of [2‐<sup>14</sup>C(U)tyrosine]arginine vasotocin with high specific radio and biological activities Journal of Labelled Compounds and Radiopharmaceuticals |
doi_str_mv |
10.1002/jlcr.2580140612 |
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Online |
finc_class_facet |
Physik Chemie und Pharmazie |
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ElectronicArticle |
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imprint |
Wiley, 1978 |
imprint_str_mv |
Wiley, 1978 |
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0362-4803 1099-1344 |
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0362-4803 1099-1344 |
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English |
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Wiley (CrossRef) |
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1978 |
publisher |
Wiley |
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ai |
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ai |
series |
Journal of Labelled Compounds and Radiopharmaceuticals |
source_id |
49 |
title |
Synthesis of [2‐14C(U)tyrosine]arginine vasotocin with high specific radio and biological activities |
title_unstemmed |
Synthesis of [2‐14C(U)tyrosine]arginine vasotocin with high specific radio and biological activities |
title_full |
Synthesis of [2‐14C(U)tyrosine]arginine vasotocin with high specific radio and biological activities |
title_fullStr |
Synthesis of [2‐14C(U)tyrosine]arginine vasotocin with high specific radio and biological activities |
title_full_unstemmed |
Synthesis of [2‐14C(U)tyrosine]arginine vasotocin with high specific radio and biological activities |
title_short |
Synthesis of [2‐14C(U)tyrosine]arginine vasotocin with high specific radio and biological activities |
title_sort |
synthesis of [2‐<sup>14</sup>c(u)tyrosine]arginine vasotocin with high specific radio and biological activities |
topic |
Organic Chemistry Spectroscopy Drug Discovery Radiology, Nuclear Medicine and imaging Biochemistry Analytical Chemistry |
url |
http://dx.doi.org/10.1002/jlcr.2580140612 |
publishDate |
1978 |
physical |
881-886 |
description |
<jats:title>Abstract</jats:title><jats:p>The synthesis of [2‐<jats:sup>14</jats:sup>C(U)tyrosine]arginine vasotocin at a specific activity of 102 mCi/mMole was performed using the solid‐phase approach of Merrifield for peptide synthesis. Following purification by gel filtrations the labeled hormone was recovered at an average yield of 40% with an avian vasodepressor activity of 408 ± 24 U/mg.</jats:p> |
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6 |
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881 |
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Journal of Labelled Compounds and Radiopharmaceuticals |
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14 |
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2024-03-01T15:24:43.675Z |
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author | Stahl, Glenn L., Walter, Roderich |
author_facet | Stahl, Glenn L., Walter, Roderich, Stahl, Glenn L., Walter, Roderich |
author_sort | stahl, glenn l. |
container_issue | 6 |
container_start_page | 881 |
container_title | Journal of Labelled Compounds and Radiopharmaceuticals |
container_volume | 14 |
description | <jats:title>Abstract</jats:title><jats:p>The synthesis of [2‐<jats:sup>14</jats:sup>C(U)tyrosine]arginine vasotocin at a specific activity of 102 mCi/mMole was performed using the solid‐phase approach of Merrifield for peptide synthesis. Following purification by gel filtrations the labeled hormone was recovered at an average yield of 40% with an avian vasodepressor activity of 408 ± 24 U/mg.</jats:p> |
doi_str_mv | 10.1002/jlcr.2580140612 |
facet_avail | Online |
finc_class_facet | Physik, Chemie und Pharmazie |
format | ElectronicArticle |
format_de105 | Article, E-Article |
format_de14 | Article, E-Article |
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id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAwMi9qbGNyLjI1ODAxNDA2MTI |
imprint | Wiley, 1978 |
imprint_str_mv | Wiley, 1978 |
institution | DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1, DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-D161 |
issn | 0362-4803, 1099-1344 |
issn_str_mv | 0362-4803, 1099-1344 |
language | English |
last_indexed | 2024-03-01T15:24:43.675Z |
match_str | stahl1978synthesisof214cutyrosineargininevasotocinwithhighspecificradioandbiologicalactivities |
mega_collection | Wiley (CrossRef) |
physical | 881-886 |
publishDate | 1978 |
publishDateSort | 1978 |
publisher | Wiley |
record_format | ai |
recordtype | ai |
series | Journal of Labelled Compounds and Radiopharmaceuticals |
source_id | 49 |
spelling | Stahl, Glenn L. Walter, Roderich 0362-4803 1099-1344 Wiley Organic Chemistry Spectroscopy Drug Discovery Radiology, Nuclear Medicine and imaging Biochemistry Analytical Chemistry http://dx.doi.org/10.1002/jlcr.2580140612 <jats:title>Abstract</jats:title><jats:p>The synthesis of [2‐<jats:sup>14</jats:sup>C(U)tyrosine]arginine vasotocin at a specific activity of 102 mCi/mMole was performed using the solid‐phase approach of Merrifield for peptide synthesis. Following purification by gel filtrations the labeled hormone was recovered at an average yield of 40% with an avian vasodepressor activity of 408 ± 24 U/mg.</jats:p> Synthesis of [2‐<sup>14</sup>C(U)tyrosine]arginine vasotocin with high specific radio and biological activities Journal of Labelled Compounds and Radiopharmaceuticals |
spellingShingle | Stahl, Glenn L., Walter, Roderich, Journal of Labelled Compounds and Radiopharmaceuticals, Synthesis of [2‐14C(U)tyrosine]arginine vasotocin with high specific radio and biological activities, Organic Chemistry, Spectroscopy, Drug Discovery, Radiology, Nuclear Medicine and imaging, Biochemistry, Analytical Chemistry |
title | Synthesis of [2‐14C(U)tyrosine]arginine vasotocin with high specific radio and biological activities |
title_full | Synthesis of [2‐14C(U)tyrosine]arginine vasotocin with high specific radio and biological activities |
title_fullStr | Synthesis of [2‐14C(U)tyrosine]arginine vasotocin with high specific radio and biological activities |
title_full_unstemmed | Synthesis of [2‐14C(U)tyrosine]arginine vasotocin with high specific radio and biological activities |
title_short | Synthesis of [2‐14C(U)tyrosine]arginine vasotocin with high specific radio and biological activities |
title_sort | synthesis of [2‐<sup>14</sup>c(u)tyrosine]arginine vasotocin with high specific radio and biological activities |
title_unstemmed | Synthesis of [2‐14C(U)tyrosine]arginine vasotocin with high specific radio and biological activities |
topic | Organic Chemistry, Spectroscopy, Drug Discovery, Radiology, Nuclear Medicine and imaging, Biochemistry, Analytical Chemistry |
url | http://dx.doi.org/10.1002/jlcr.2580140612 |