author_facet Zawko, Scott A.
Schmidt, Christine E.
Zawko, Scott A.
Schmidt, Christine E.
author Zawko, Scott A.
Schmidt, Christine E.
spellingShingle Zawko, Scott A.
Schmidt, Christine E.
Journal of Biomedical Materials Research Part A
Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers
Metals and Alloys
Biomedical Engineering
Biomaterials
Ceramics and Composites
author_sort zawko, scott a.
spelling Zawko, Scott A. Schmidt, Christine E. 1549-3296 1552-4965 Wiley Metals and Alloys Biomedical Engineering Biomaterials Ceramics and Composites http://dx.doi.org/10.1002/jbm.a.33114 <jats:title>Abstract</jats:title><jats:p>An objective of tissue engineering is to create synthetic polymer scaffolds with a fibrillar microstructure similar to the extracellular matrix. Here, we present a novel method for creating polymer fibers using the layer‐by‐layer method and sacrificial templates composed of sodium soap fibers. Soap fibers were prepared from neutralized fatty acids using a sodium chloride crystal dissolution method. Polyelectrolyte multilayers (PEMs) of polystyrene sulfonate and polyallylamine hydrochloride were deposited onto the soap fibers, crosslinked with glutaraldehyde, and then the soap fibers were leached with warm water and ethanol. The morphology of the resulting PEM structures was a dense network of fibers surrounded by a nonfibrillar matrix. Microscopy revealed that the PEM fibers were solid structures, presumably composed of polyelectrolytes complexed with residual fatty acids. These fibrillar PEM films were found to support the attachment of human dermal fibroblasts. © 2011 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 2011.</jats:p> Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers Journal of Biomedical Materials Research Part A
doi_str_mv 10.1002/jbm.a.33114
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series Journal of Biomedical Materials Research Part A
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title Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers
title_unstemmed Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers
title_full Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers
title_fullStr Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers
title_full_unstemmed Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers
title_short Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers
title_sort fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers
topic Metals and Alloys
Biomedical Engineering
Biomaterials
Ceramics and Composites
url http://dx.doi.org/10.1002/jbm.a.33114
publishDate 2011
physical 287-295
description <jats:title>Abstract</jats:title><jats:p>An objective of tissue engineering is to create synthetic polymer scaffolds with a fibrillar microstructure similar to the extracellular matrix. Here, we present a novel method for creating polymer fibers using the layer‐by‐layer method and sacrificial templates composed of sodium soap fibers. Soap fibers were prepared from neutralized fatty acids using a sodium chloride crystal dissolution method. Polyelectrolyte multilayers (PEMs) of polystyrene sulfonate and polyallylamine hydrochloride were deposited onto the soap fibers, crosslinked with glutaraldehyde, and then the soap fibers were leached with warm water and ethanol. The morphology of the resulting PEM structures was a dense network of fibers surrounded by a nonfibrillar matrix. Microscopy revealed that the PEM fibers were solid structures, presumably composed of polyelectrolytes complexed with residual fatty acids. These fibrillar PEM films were found to support the attachment of human dermal fibroblasts. © 2011 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 2011.</jats:p>
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author Zawko, Scott A., Schmidt, Christine E.
author_facet Zawko, Scott A., Schmidt, Christine E., Zawko, Scott A., Schmidt, Christine E.
author_sort zawko, scott a.
container_issue 2
container_start_page 287
container_title Journal of Biomedical Materials Research Part A
container_volume 98A
description <jats:title>Abstract</jats:title><jats:p>An objective of tissue engineering is to create synthetic polymer scaffolds with a fibrillar microstructure similar to the extracellular matrix. Here, we present a novel method for creating polymer fibers using the layer‐by‐layer method and sacrificial templates composed of sodium soap fibers. Soap fibers were prepared from neutralized fatty acids using a sodium chloride crystal dissolution method. Polyelectrolyte multilayers (PEMs) of polystyrene sulfonate and polyallylamine hydrochloride were deposited onto the soap fibers, crosslinked with glutaraldehyde, and then the soap fibers were leached with warm water and ethanol. The morphology of the resulting PEM structures was a dense network of fibers surrounded by a nonfibrillar matrix. Microscopy revealed that the PEM fibers were solid structures, presumably composed of polyelectrolytes complexed with residual fatty acids. These fibrillar PEM films were found to support the attachment of human dermal fibroblasts. © 2011 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 2011.</jats:p>
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spelling Zawko, Scott A. Schmidt, Christine E. 1549-3296 1552-4965 Wiley Metals and Alloys Biomedical Engineering Biomaterials Ceramics and Composites http://dx.doi.org/10.1002/jbm.a.33114 <jats:title>Abstract</jats:title><jats:p>An objective of tissue engineering is to create synthetic polymer scaffolds with a fibrillar microstructure similar to the extracellular matrix. Here, we present a novel method for creating polymer fibers using the layer‐by‐layer method and sacrificial templates composed of sodium soap fibers. Soap fibers were prepared from neutralized fatty acids using a sodium chloride crystal dissolution method. Polyelectrolyte multilayers (PEMs) of polystyrene sulfonate and polyallylamine hydrochloride were deposited onto the soap fibers, crosslinked with glutaraldehyde, and then the soap fibers were leached with warm water and ethanol. The morphology of the resulting PEM structures was a dense network of fibers surrounded by a nonfibrillar matrix. Microscopy revealed that the PEM fibers were solid structures, presumably composed of polyelectrolytes complexed with residual fatty acids. These fibrillar PEM films were found to support the attachment of human dermal fibroblasts. © 2011 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 2011.</jats:p> Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers Journal of Biomedical Materials Research Part A
spellingShingle Zawko, Scott A., Schmidt, Christine E., Journal of Biomedical Materials Research Part A, Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers, Metals and Alloys, Biomedical Engineering, Biomaterials, Ceramics and Composites
title Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers
title_full Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers
title_fullStr Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers
title_full_unstemmed Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers
title_short Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers
title_sort fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers
title_unstemmed Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers
topic Metals and Alloys, Biomedical Engineering, Biomaterials, Ceramics and Composites
url http://dx.doi.org/10.1002/jbm.a.33114