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Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers
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Zeitschriftentitel: | Journal of Biomedical Materials Research Part A |
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Personen und Körperschaften: | , |
In: | Journal of Biomedical Materials Research Part A, 98A, 2011, 2, S. 287-295 |
Format: | E-Article |
Sprache: | Englisch |
veröffentlicht: |
Wiley
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Schlagwörter: |
author_facet |
Zawko, Scott A. Schmidt, Christine E. Zawko, Scott A. Schmidt, Christine E. |
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author |
Zawko, Scott A. Schmidt, Christine E. |
spellingShingle |
Zawko, Scott A. Schmidt, Christine E. Journal of Biomedical Materials Research Part A Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers Metals and Alloys Biomedical Engineering Biomaterials Ceramics and Composites |
author_sort |
zawko, scott a. |
spelling |
Zawko, Scott A. Schmidt, Christine E. 1549-3296 1552-4965 Wiley Metals and Alloys Biomedical Engineering Biomaterials Ceramics and Composites http://dx.doi.org/10.1002/jbm.a.33114 <jats:title>Abstract</jats:title><jats:p>An objective of tissue engineering is to create synthetic polymer scaffolds with a fibrillar microstructure similar to the extracellular matrix. Here, we present a novel method for creating polymer fibers using the layer‐by‐layer method and sacrificial templates composed of sodium soap fibers. Soap fibers were prepared from neutralized fatty acids using a sodium chloride crystal dissolution method. Polyelectrolyte multilayers (PEMs) of polystyrene sulfonate and polyallylamine hydrochloride were deposited onto the soap fibers, crosslinked with glutaraldehyde, and then the soap fibers were leached with warm water and ethanol. The morphology of the resulting PEM structures was a dense network of fibers surrounded by a nonfibrillar matrix. Microscopy revealed that the PEM fibers were solid structures, presumably composed of polyelectrolytes complexed with residual fatty acids. These fibrillar PEM films were found to support the attachment of human dermal fibroblasts. © 2011 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 2011.</jats:p> Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers Journal of Biomedical Materials Research Part A |
doi_str_mv |
10.1002/jbm.a.33114 |
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Chemie und Pharmazie Biologie Medizin Technik |
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title |
Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers |
title_unstemmed |
Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers |
title_full |
Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers |
title_fullStr |
Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers |
title_full_unstemmed |
Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers |
title_short |
Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers |
title_sort |
fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers |
topic |
Metals and Alloys Biomedical Engineering Biomaterials Ceramics and Composites |
url |
http://dx.doi.org/10.1002/jbm.a.33114 |
publishDate |
2011 |
physical |
287-295 |
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<jats:title>Abstract</jats:title><jats:p>An objective of tissue engineering is to create synthetic polymer scaffolds with a fibrillar microstructure similar to the extracellular matrix. Here, we present a novel method for creating polymer fibers using the layer‐by‐layer method and sacrificial templates composed of sodium soap fibers. Soap fibers were prepared from neutralized fatty acids using a sodium chloride crystal dissolution method. Polyelectrolyte multilayers (PEMs) of polystyrene sulfonate and polyallylamine hydrochloride were deposited onto the soap fibers, crosslinked with glutaraldehyde, and then the soap fibers were leached with warm water and ethanol. The morphology of the resulting PEM structures was a dense network of fibers surrounded by a nonfibrillar matrix. Microscopy revealed that the PEM fibers were solid structures, presumably composed of polyelectrolytes complexed with residual fatty acids. These fibrillar PEM films were found to support the attachment of human dermal fibroblasts. © 2011 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 2011.</jats:p> |
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author | Zawko, Scott A., Schmidt, Christine E. |
author_facet | Zawko, Scott A., Schmidt, Christine E., Zawko, Scott A., Schmidt, Christine E. |
author_sort | zawko, scott a. |
container_issue | 2 |
container_start_page | 287 |
container_title | Journal of Biomedical Materials Research Part A |
container_volume | 98A |
description | <jats:title>Abstract</jats:title><jats:p>An objective of tissue engineering is to create synthetic polymer scaffolds with a fibrillar microstructure similar to the extracellular matrix. Here, we present a novel method for creating polymer fibers using the layer‐by‐layer method and sacrificial templates composed of sodium soap fibers. Soap fibers were prepared from neutralized fatty acids using a sodium chloride crystal dissolution method. Polyelectrolyte multilayers (PEMs) of polystyrene sulfonate and polyallylamine hydrochloride were deposited onto the soap fibers, crosslinked with glutaraldehyde, and then the soap fibers were leached with warm water and ethanol. The morphology of the resulting PEM structures was a dense network of fibers surrounded by a nonfibrillar matrix. Microscopy revealed that the PEM fibers were solid structures, presumably composed of polyelectrolytes complexed with residual fatty acids. These fibrillar PEM films were found to support the attachment of human dermal fibroblasts. © 2011 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 2011.</jats:p> |
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spelling | Zawko, Scott A. Schmidt, Christine E. 1549-3296 1552-4965 Wiley Metals and Alloys Biomedical Engineering Biomaterials Ceramics and Composites http://dx.doi.org/10.1002/jbm.a.33114 <jats:title>Abstract</jats:title><jats:p>An objective of tissue engineering is to create synthetic polymer scaffolds with a fibrillar microstructure similar to the extracellular matrix. Here, we present a novel method for creating polymer fibers using the layer‐by‐layer method and sacrificial templates composed of sodium soap fibers. Soap fibers were prepared from neutralized fatty acids using a sodium chloride crystal dissolution method. Polyelectrolyte multilayers (PEMs) of polystyrene sulfonate and polyallylamine hydrochloride were deposited onto the soap fibers, crosslinked with glutaraldehyde, and then the soap fibers were leached with warm water and ethanol. The morphology of the resulting PEM structures was a dense network of fibers surrounded by a nonfibrillar matrix. Microscopy revealed that the PEM fibers were solid structures, presumably composed of polyelectrolytes complexed with residual fatty acids. These fibrillar PEM films were found to support the attachment of human dermal fibroblasts. © 2011 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 2011.</jats:p> Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers Journal of Biomedical Materials Research Part A |
spellingShingle | Zawko, Scott A., Schmidt, Christine E., Journal of Biomedical Materials Research Part A, Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers, Metals and Alloys, Biomedical Engineering, Biomaterials, Ceramics and Composites |
title | Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers |
title_full | Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers |
title_fullStr | Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers |
title_full_unstemmed | Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers |
title_short | Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers |
title_sort | fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers |
title_unstemmed | Fibrillar films obtained from sodium soap fibers and polyelectrolyte multilayers |
topic | Metals and Alloys, Biomedical Engineering, Biomaterials, Ceramics and Composites |
url | http://dx.doi.org/10.1002/jbm.a.33114 |