author_facet Herrmann, Markus
Nkuiya, Bruno
Herrmann, Markus
Nkuiya, Bruno
author Herrmann, Markus
Nkuiya, Bruno
spellingShingle Herrmann, Markus
Nkuiya, Bruno
Health Economics
Inducing optimal substitution between antibiotics under open access to the resource of antibiotic susceptibility
Health Policy
author_sort herrmann, markus
spelling Herrmann, Markus Nkuiya, Bruno 1057-9230 1099-1050 Wiley Health Policy http://dx.doi.org/10.1002/hec.3348 <jats:title>Summary</jats:title><jats:p>This paper designs a bio‐economic model to examine the use of substitute antibiotic drugs (analogs) sold by an industry that has open access to the resource of the antibiotic class's susceptibility (treatment effectiveness). Antibiotics are characterized by different expected recovery rates and production costs, which in conjunction with the class's treatment susceptibility determines their relative effectiveness. Our analysis reveals that the high‐quality antibiotic drug loses its comparative advantage over time making the low‐quality drug the treatment of last resort in the market equilibrium and the social optimum when antibiotic susceptibility cannot replenish. However, when antibiotic susceptibility is renewable, both antibiotics may be used in the long run, and the comparative advantage of the high‐quality drug may be restored in the social optimum that allows lowering infection in the long run. We develop the optimal tax/subsidy scheme that would induce antibiotic producers under open access to behave optimally and account for the social cost of infection and value of antibiotic susceptibility. We show that the welfare loss associated with the uncorrected open‐access allocation is highest; when the resource of antibiotic susceptibility is non‐renewable, high morbidity costs are incurred by individuals, and low social discount rates apply. Copyright © 2016 John Wiley &amp; Sons, Ltd.</jats:p> Inducing optimal substitution between antibiotics under open access to the resource of antibiotic susceptibility Health Economics
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title Inducing optimal substitution between antibiotics under open access to the resource of antibiotic susceptibility
title_unstemmed Inducing optimal substitution between antibiotics under open access to the resource of antibiotic susceptibility
title_full Inducing optimal substitution between antibiotics under open access to the resource of antibiotic susceptibility
title_fullStr Inducing optimal substitution between antibiotics under open access to the resource of antibiotic susceptibility
title_full_unstemmed Inducing optimal substitution between antibiotics under open access to the resource of antibiotic susceptibility
title_short Inducing optimal substitution between antibiotics under open access to the resource of antibiotic susceptibility
title_sort inducing optimal substitution between antibiotics under open access to the resource of antibiotic susceptibility
topic Health Policy
url http://dx.doi.org/10.1002/hec.3348
publishDate 2017
physical 703-723
description <jats:title>Summary</jats:title><jats:p>This paper designs a bio‐economic model to examine the use of substitute antibiotic drugs (analogs) sold by an industry that has open access to the resource of the antibiotic class's susceptibility (treatment effectiveness). Antibiotics are characterized by different expected recovery rates and production costs, which in conjunction with the class's treatment susceptibility determines their relative effectiveness. Our analysis reveals that the high‐quality antibiotic drug loses its comparative advantage over time making the low‐quality drug the treatment of last resort in the market equilibrium and the social optimum when antibiotic susceptibility cannot replenish. However, when antibiotic susceptibility is renewable, both antibiotics may be used in the long run, and the comparative advantage of the high‐quality drug may be restored in the social optimum that allows lowering infection in the long run. We develop the optimal tax/subsidy scheme that would induce antibiotic producers under open access to behave optimally and account for the social cost of infection and value of antibiotic susceptibility. We show that the welfare loss associated with the uncorrected open‐access allocation is highest; when the resource of antibiotic susceptibility is non‐renewable, high morbidity costs are incurred by individuals, and low social discount rates apply. Copyright © 2016 John Wiley &amp; Sons, Ltd.</jats:p>
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author Herrmann, Markus, Nkuiya, Bruno
author_facet Herrmann, Markus, Nkuiya, Bruno, Herrmann, Markus, Nkuiya, Bruno
author_sort herrmann, markus
container_issue 6
container_start_page 703
container_title Health Economics
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description <jats:title>Summary</jats:title><jats:p>This paper designs a bio‐economic model to examine the use of substitute antibiotic drugs (analogs) sold by an industry that has open access to the resource of the antibiotic class's susceptibility (treatment effectiveness). Antibiotics are characterized by different expected recovery rates and production costs, which in conjunction with the class's treatment susceptibility determines their relative effectiveness. Our analysis reveals that the high‐quality antibiotic drug loses its comparative advantage over time making the low‐quality drug the treatment of last resort in the market equilibrium and the social optimum when antibiotic susceptibility cannot replenish. However, when antibiotic susceptibility is renewable, both antibiotics may be used in the long run, and the comparative advantage of the high‐quality drug may be restored in the social optimum that allows lowering infection in the long run. We develop the optimal tax/subsidy scheme that would induce antibiotic producers under open access to behave optimally and account for the social cost of infection and value of antibiotic susceptibility. We show that the welfare loss associated with the uncorrected open‐access allocation is highest; when the resource of antibiotic susceptibility is non‐renewable, high morbidity costs are incurred by individuals, and low social discount rates apply. Copyright © 2016 John Wiley &amp; Sons, Ltd.</jats:p>
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spelling Herrmann, Markus Nkuiya, Bruno 1057-9230 1099-1050 Wiley Health Policy http://dx.doi.org/10.1002/hec.3348 <jats:title>Summary</jats:title><jats:p>This paper designs a bio‐economic model to examine the use of substitute antibiotic drugs (analogs) sold by an industry that has open access to the resource of the antibiotic class's susceptibility (treatment effectiveness). Antibiotics are characterized by different expected recovery rates and production costs, which in conjunction with the class's treatment susceptibility determines their relative effectiveness. Our analysis reveals that the high‐quality antibiotic drug loses its comparative advantage over time making the low‐quality drug the treatment of last resort in the market equilibrium and the social optimum when antibiotic susceptibility cannot replenish. However, when antibiotic susceptibility is renewable, both antibiotics may be used in the long run, and the comparative advantage of the high‐quality drug may be restored in the social optimum that allows lowering infection in the long run. We develop the optimal tax/subsidy scheme that would induce antibiotic producers under open access to behave optimally and account for the social cost of infection and value of antibiotic susceptibility. We show that the welfare loss associated with the uncorrected open‐access allocation is highest; when the resource of antibiotic susceptibility is non‐renewable, high morbidity costs are incurred by individuals, and low social discount rates apply. Copyright © 2016 John Wiley &amp; Sons, Ltd.</jats:p> Inducing optimal substitution between antibiotics under open access to the resource of antibiotic susceptibility Health Economics
spellingShingle Herrmann, Markus, Nkuiya, Bruno, Health Economics, Inducing optimal substitution between antibiotics under open access to the resource of antibiotic susceptibility, Health Policy
title Inducing optimal substitution between antibiotics under open access to the resource of antibiotic susceptibility
title_full Inducing optimal substitution between antibiotics under open access to the resource of antibiotic susceptibility
title_fullStr Inducing optimal substitution between antibiotics under open access to the resource of antibiotic susceptibility
title_full_unstemmed Inducing optimal substitution between antibiotics under open access to the resource of antibiotic susceptibility
title_short Inducing optimal substitution between antibiotics under open access to the resource of antibiotic susceptibility
title_sort inducing optimal substitution between antibiotics under open access to the resource of antibiotic susceptibility
title_unstemmed Inducing optimal substitution between antibiotics under open access to the resource of antibiotic susceptibility
topic Health Policy
url http://dx.doi.org/10.1002/hec.3348