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Quantitative trait locus detection using combined linkage/disequilibrium analysis
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| Zeitschriftentitel: | Genetic Epidemiology |
|---|---|
| Personen und Körperschaften: | , , , |
| In: | Genetic Epidemiology, 17, 1999, S1 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Wiley
|
| Schlagwörter: |
| author_facet |
Almasy, Laura Williams, Jeff T. Dyer, Thomas D. Blangero, John Almasy, Laura Williams, Jeff T. Dyer, Thomas D. Blangero, John |
|---|---|
| author |
Almasy, Laura Williams, Jeff T. Dyer, Thomas D. Blangero, John |
| spellingShingle |
Almasy, Laura Williams, Jeff T. Dyer, Thomas D. Blangero, John Genetic Epidemiology Quantitative trait locus detection using combined linkage/disequilibrium analysis Genetics (clinical) Epidemiology |
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almasy, laura |
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Almasy, Laura Williams, Jeff T. Dyer, Thomas D. Blangero, John 0741-0395 1098-2272 Wiley Genetics (clinical) Epidemiology http://dx.doi.org/10.1002/gepi.1370170706 <jats:title>Abstract</jats:title><jats:p>We describe an extension of the variance component linkage method that augments identity‐by‐descent information from relatives with identity‐by‐state information from unrelated individuals, exploiting disequilibrium to facilitate fine mapping of quantitative trait loci. An advantage of the combined linkage/disequilibrium test is that it detects association only in the presence of linkage and is not biased by population stratification.</jats:p> Quantitative trait locus detection using combined linkage/disequilibrium analysis Genetic Epidemiology |
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Wiley, 1999 |
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Wiley, 1999 |
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1999 |
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Genetic Epidemiology |
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| title |
Quantitative trait locus detection using combined linkage/disequilibrium analysis |
| title_unstemmed |
Quantitative trait locus detection using combined linkage/disequilibrium analysis |
| title_full |
Quantitative trait locus detection using combined linkage/disequilibrium analysis |
| title_fullStr |
Quantitative trait locus detection using combined linkage/disequilibrium analysis |
| title_full_unstemmed |
Quantitative trait locus detection using combined linkage/disequilibrium analysis |
| title_short |
Quantitative trait locus detection using combined linkage/disequilibrium analysis |
| title_sort |
quantitative trait locus detection using combined linkage/disequilibrium analysis |
| topic |
Genetics (clinical) Epidemiology |
| url |
http://dx.doi.org/10.1002/gepi.1370170706 |
| publishDate |
1999 |
| physical |
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<jats:title>Abstract</jats:title><jats:p>We describe an extension of the variance component linkage method that augments identity‐by‐descent information from relatives with identity‐by‐state information from unrelated individuals, exploiting disequilibrium to facilitate fine mapping of quantitative trait loci. An advantage of the combined linkage/disequilibrium test is that it detects association only in the presence of linkage and is not biased by population stratification.</jats:p> |
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| author | Almasy, Laura, Williams, Jeff T., Dyer, Thomas D., Blangero, John |
| author_facet | Almasy, Laura, Williams, Jeff T., Dyer, Thomas D., Blangero, John, Almasy, Laura, Williams, Jeff T., Dyer, Thomas D., Blangero, John |
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| description | <jats:title>Abstract</jats:title><jats:p>We describe an extension of the variance component linkage method that augments identity‐by‐descent information from relatives with identity‐by‐state information from unrelated individuals, exploiting disequilibrium to facilitate fine mapping of quantitative trait loci. An advantage of the combined linkage/disequilibrium test is that it detects association only in the presence of linkage and is not biased by population stratification.</jats:p> |
| doi_str_mv | 10.1002/gepi.1370170706 |
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| id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAwMi9nZXBpLjEzNzAxNzA3MDY |
| imprint | Wiley, 1999 |
| imprint_str_mv | Wiley, 1999 |
| institution | DE-D275, DE-Bn3, DE-Brt1, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1, DE-L229 |
| issn | 0741-0395, 1098-2272 |
| issn_str_mv | 0741-0395, 1098-2272 |
| language | English |
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| series | Genetic Epidemiology |
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| spelling | Almasy, Laura Williams, Jeff T. Dyer, Thomas D. Blangero, John 0741-0395 1098-2272 Wiley Genetics (clinical) Epidemiology http://dx.doi.org/10.1002/gepi.1370170706 <jats:title>Abstract</jats:title><jats:p>We describe an extension of the variance component linkage method that augments identity‐by‐descent information from relatives with identity‐by‐state information from unrelated individuals, exploiting disequilibrium to facilitate fine mapping of quantitative trait loci. An advantage of the combined linkage/disequilibrium test is that it detects association only in the presence of linkage and is not biased by population stratification.</jats:p> Quantitative trait locus detection using combined linkage/disequilibrium analysis Genetic Epidemiology |
| spellingShingle | Almasy, Laura, Williams, Jeff T., Dyer, Thomas D., Blangero, John, Genetic Epidemiology, Quantitative trait locus detection using combined linkage/disequilibrium analysis, Genetics (clinical), Epidemiology |
| title | Quantitative trait locus detection using combined linkage/disequilibrium analysis |
| title_full | Quantitative trait locus detection using combined linkage/disequilibrium analysis |
| title_fullStr | Quantitative trait locus detection using combined linkage/disequilibrium analysis |
| title_full_unstemmed | Quantitative trait locus detection using combined linkage/disequilibrium analysis |
| title_short | Quantitative trait locus detection using combined linkage/disequilibrium analysis |
| title_sort | quantitative trait locus detection using combined linkage/disequilibrium analysis |
| title_unstemmed | Quantitative trait locus detection using combined linkage/disequilibrium analysis |
| topic | Genetics (clinical), Epidemiology |
| url | http://dx.doi.org/10.1002/gepi.1370170706 |