Eintrag weiter verarbeiten
Base‐pair mutations caused by six aliphatic epoxides in salmonella typhimurium TA100, TA104, TA4001, and TA4006
Gespeichert in:
| Zeitschriftentitel: | Environmental and Molecular Mutagenesis |
|---|---|
| Personen und Körperschaften: | , , |
| In: | Environmental and Molecular Mutagenesis, 21, 1993, 3, S. 253-257 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Wiley
|
| Schlagwörter: |
| author_facet |
Einistö, P. Hooberman, B. H. Sinsheimer, J. E. Einistö, P. Hooberman, B. H. Sinsheimer, J. E. |
|---|---|
| author |
Einistö, P. Hooberman, B. H. Sinsheimer, J. E. |
| spellingShingle |
Einistö, P. Hooberman, B. H. Sinsheimer, J. E. Environmental and Molecular Mutagenesis Base‐pair mutations caused by six aliphatic epoxides in salmonella typhimurium TA100, TA104, TA4001, and TA4006 Health, Toxicology and Mutagenesis Genetics (clinical) Epidemiology |
| author_sort |
einistö, p. |
| spelling |
Einistö, P. Hooberman, B. H. Sinsheimer, J. E. 0893-6692 1098-2280 Wiley Health, Toxicology and Mutagenesis Genetics (clinical) Epidemiology http://dx.doi.org/10.1002/em.2850210308 <jats:title>Abstract</jats:title><jats:p><jats:italic>Salmonella typhimurium</jats:italic> strains TA100, TA104, TA4001, and TA4006 were used to detect the base‐pair mutations caused by six aliphatic epoxides: chloropropylene oxide, glycidyl 1‐naphthyl ether, glycidyl 4‐nitrophenyl ether, 1‐naphthyl‐propylene oxide, styrene oxide, and trichloropropylene oxide. Dose‐mutagenicity relationships could be established for all six epoxides in strains TA100 and TA104 but not in strains TA4001 and TA4006. These results, together with the lack of sensitivity of the TA100 revertants to DL‐1,2,4‐triazole‐3‐alanine, indicate CG→TA transitions and/or CG→AT transversions are of major importance for mutations induced by these epoxides in <jats:italic>Salmonella</jats:italic> TA100 and possibly TA104. In addition, since the reproducibility of the effect of the triazole on TA104 reversions was poor, TA→AT transversions were not eliminated as also contributing to the mutagenicity of these epoxides in this <jats:italic>Salmonella</jats:italic> strain. © 1993 Wiley‐Liss, Inc.</jats:p> Base‐pair mutations caused by six aliphatic epoxides in salmonella typhimurium TA100, TA104, TA4001, and TA4006 Environmental and Molecular Mutagenesis |
| doi_str_mv |
10.1002/em.2850210308 |
| facet_avail |
Online |
| finc_class_facet |
Medizin |
| format |
ElectronicArticle |
| fullrecord |
blob:ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAwMi9lbS4yODUwMjEwMzA4 |
| id |
ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAwMi9lbS4yODUwMjEwMzA4 |
| institution |
DE-Ch1 DE-L229 DE-D275 DE-Bn3 DE-Brt1 DE-D161 DE-Gla1 DE-Zi4 DE-15 DE-Pl11 DE-Rs1 DE-105 DE-14 |
| imprint |
Wiley, 1993 |
| imprint_str_mv |
Wiley, 1993 |
| issn |
0893-6692 1098-2280 |
| issn_str_mv |
0893-6692 1098-2280 |
| language |
English |
| mega_collection |
Wiley (CrossRef) |
| match_str |
einisto1993basepairmutationscausedbysixaliphaticepoxidesinsalmonellatyphimuriumta100ta104ta4001andta4006 |
| publishDateSort |
1993 |
| publisher |
Wiley |
| recordtype |
ai |
| record_format |
ai |
| series |
Environmental and Molecular Mutagenesis |
| source_id |
49 |
| title |
Base‐pair mutations caused by six aliphatic epoxides in salmonella typhimurium TA100, TA104, TA4001, and TA4006 |
| title_unstemmed |
Base‐pair mutations caused by six aliphatic epoxides in salmonella typhimurium TA100, TA104, TA4001, and TA4006 |
| title_full |
Base‐pair mutations caused by six aliphatic epoxides in salmonella typhimurium TA100, TA104, TA4001, and TA4006 |
| title_fullStr |
Base‐pair mutations caused by six aliphatic epoxides in salmonella typhimurium TA100, TA104, TA4001, and TA4006 |
| title_full_unstemmed |
Base‐pair mutations caused by six aliphatic epoxides in salmonella typhimurium TA100, TA104, TA4001, and TA4006 |
| title_short |
Base‐pair mutations caused by six aliphatic epoxides in salmonella typhimurium TA100, TA104, TA4001, and TA4006 |
| title_sort |
base‐pair mutations caused by six aliphatic epoxides in salmonella typhimurium ta100, ta104, ta4001, and ta4006 |
| topic |
Health, Toxicology and Mutagenesis Genetics (clinical) Epidemiology |
| url |
http://dx.doi.org/10.1002/em.2850210308 |
| publishDate |
1993 |
| physical |
253-257 |
| description |
<jats:title>Abstract</jats:title><jats:p><jats:italic>Salmonella typhimurium</jats:italic> strains TA100, TA104, TA4001, and TA4006 were used to detect the base‐pair mutations caused by six aliphatic epoxides: chloropropylene oxide, glycidyl 1‐naphthyl ether, glycidyl 4‐nitrophenyl ether, 1‐naphthyl‐propylene oxide, styrene oxide, and trichloropropylene oxide. Dose‐mutagenicity relationships could be established for all six epoxides in strains TA100 and TA104 but not in strains TA4001 and TA4006. These results, together with the lack of sensitivity of the TA100 revertants to DL‐1,2,4‐triazole‐3‐alanine, indicate CG→TA transitions and/or CG→AT transversions are of major importance for mutations induced by these epoxides in <jats:italic>Salmonella</jats:italic> TA100 and possibly TA104. In addition, since the reproducibility of the effect of the triazole on TA104 reversions was poor, TA→AT transversions were not eliminated as also contributing to the mutagenicity of these epoxides in this <jats:italic>Salmonella</jats:italic> strain. © 1993 Wiley‐Liss, Inc.</jats:p> |
| container_issue |
3 |
| container_start_page |
253 |
| container_title |
Environmental and Molecular Mutagenesis |
| container_volume |
21 |
| format_de105 |
Article, E-Article |
| format_de14 |
Article, E-Article |
| format_de15 |
Article, E-Article |
| format_de520 |
Article, E-Article |
| format_de540 |
Article, E-Article |
| format_dech1 |
Article, E-Article |
| format_ded117 |
Article, E-Article |
| format_degla1 |
E-Article |
| format_del152 |
Buch |
| format_del189 |
Article, E-Article |
| format_dezi4 |
Article |
| format_dezwi2 |
Article, E-Article |
| format_finc |
Article, E-Article |
| format_nrw |
Article, E-Article |
| _version_ |
1792336363135172611 |
| geogr_code |
not assigned |
| last_indexed |
2024-03-01T14:59:15.816Z |
| geogr_code_person |
not assigned |
| openURL |
url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=Base%E2%80%90pair+mutations+caused+by+six+aliphatic+epoxides+in+salmonella+typhimurium+TA100%2C+TA104%2C+TA4001%2C+and+TA4006&rft.date=1993-01-01&genre=article&issn=1098-2280&volume=21&issue=3&spage=253&epage=257&pages=253-257&jtitle=Environmental+and+Molecular+Mutagenesis&atitle=Base%E2%80%90pair+mutations+caused+by+six+aliphatic+epoxides+in+salmonella+typhimurium+TA100%2C+TA104%2C+TA4001%2C+and+TA4006&aulast=Sinsheimer&aufirst=J.+E.&rft_id=info%3Adoi%2F10.1002%2Fem.2850210308&rft.language%5B0%5D=eng |
| SOLR | |
| _version_ | 1792336363135172611 |
| author | Einistö, P., Hooberman, B. H., Sinsheimer, J. E. |
| author_facet | Einistö, P., Hooberman, B. H., Sinsheimer, J. E., Einistö, P., Hooberman, B. H., Sinsheimer, J. E. |
| author_sort | einistö, p. |
| container_issue | 3 |
| container_start_page | 253 |
| container_title | Environmental and Molecular Mutagenesis |
| container_volume | 21 |
| description | <jats:title>Abstract</jats:title><jats:p><jats:italic>Salmonella typhimurium</jats:italic> strains TA100, TA104, TA4001, and TA4006 were used to detect the base‐pair mutations caused by six aliphatic epoxides: chloropropylene oxide, glycidyl 1‐naphthyl ether, glycidyl 4‐nitrophenyl ether, 1‐naphthyl‐propylene oxide, styrene oxide, and trichloropropylene oxide. Dose‐mutagenicity relationships could be established for all six epoxides in strains TA100 and TA104 but not in strains TA4001 and TA4006. These results, together with the lack of sensitivity of the TA100 revertants to DL‐1,2,4‐triazole‐3‐alanine, indicate CG→TA transitions and/or CG→AT transversions are of major importance for mutations induced by these epoxides in <jats:italic>Salmonella</jats:italic> TA100 and possibly TA104. In addition, since the reproducibility of the effect of the triazole on TA104 reversions was poor, TA→AT transversions were not eliminated as also contributing to the mutagenicity of these epoxides in this <jats:italic>Salmonella</jats:italic> strain. © 1993 Wiley‐Liss, Inc.</jats:p> |
| doi_str_mv | 10.1002/em.2850210308 |
| facet_avail | Online |
| finc_class_facet | Medizin |
| format | ElectronicArticle |
| format_de105 | Article, E-Article |
| format_de14 | Article, E-Article |
| format_de15 | Article, E-Article |
| format_de520 | Article, E-Article |
| format_de540 | Article, E-Article |
| format_dech1 | Article, E-Article |
| format_ded117 | Article, E-Article |
| format_degla1 | E-Article |
| format_del152 | Buch |
| format_del189 | Article, E-Article |
| format_dezi4 | Article |
| format_dezwi2 | Article, E-Article |
| format_finc | Article, E-Article |
| format_nrw | Article, E-Article |
| geogr_code | not assigned |
| geogr_code_person | not assigned |
| id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAwMi9lbS4yODUwMjEwMzA4 |
| imprint | Wiley, 1993 |
| imprint_str_mv | Wiley, 1993 |
| institution | DE-Ch1, DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14 |
| issn | 0893-6692, 1098-2280 |
| issn_str_mv | 0893-6692, 1098-2280 |
| language | English |
| last_indexed | 2024-03-01T14:59:15.816Z |
| match_str | einisto1993basepairmutationscausedbysixaliphaticepoxidesinsalmonellatyphimuriumta100ta104ta4001andta4006 |
| mega_collection | Wiley (CrossRef) |
| physical | 253-257 |
| publishDate | 1993 |
| publishDateSort | 1993 |
| publisher | Wiley |
| record_format | ai |
| recordtype | ai |
| series | Environmental and Molecular Mutagenesis |
| source_id | 49 |
| spelling | Einistö, P. Hooberman, B. H. Sinsheimer, J. E. 0893-6692 1098-2280 Wiley Health, Toxicology and Mutagenesis Genetics (clinical) Epidemiology http://dx.doi.org/10.1002/em.2850210308 <jats:title>Abstract</jats:title><jats:p><jats:italic>Salmonella typhimurium</jats:italic> strains TA100, TA104, TA4001, and TA4006 were used to detect the base‐pair mutations caused by six aliphatic epoxides: chloropropylene oxide, glycidyl 1‐naphthyl ether, glycidyl 4‐nitrophenyl ether, 1‐naphthyl‐propylene oxide, styrene oxide, and trichloropropylene oxide. Dose‐mutagenicity relationships could be established for all six epoxides in strains TA100 and TA104 but not in strains TA4001 and TA4006. These results, together with the lack of sensitivity of the TA100 revertants to DL‐1,2,4‐triazole‐3‐alanine, indicate CG→TA transitions and/or CG→AT transversions are of major importance for mutations induced by these epoxides in <jats:italic>Salmonella</jats:italic> TA100 and possibly TA104. In addition, since the reproducibility of the effect of the triazole on TA104 reversions was poor, TA→AT transversions were not eliminated as also contributing to the mutagenicity of these epoxides in this <jats:italic>Salmonella</jats:italic> strain. © 1993 Wiley‐Liss, Inc.</jats:p> Base‐pair mutations caused by six aliphatic epoxides in salmonella typhimurium TA100, TA104, TA4001, and TA4006 Environmental and Molecular Mutagenesis |
| spellingShingle | Einistö, P., Hooberman, B. H., Sinsheimer, J. E., Environmental and Molecular Mutagenesis, Base‐pair mutations caused by six aliphatic epoxides in salmonella typhimurium TA100, TA104, TA4001, and TA4006, Health, Toxicology and Mutagenesis, Genetics (clinical), Epidemiology |
| title | Base‐pair mutations caused by six aliphatic epoxides in salmonella typhimurium TA100, TA104, TA4001, and TA4006 |
| title_full | Base‐pair mutations caused by six aliphatic epoxides in salmonella typhimurium TA100, TA104, TA4001, and TA4006 |
| title_fullStr | Base‐pair mutations caused by six aliphatic epoxides in salmonella typhimurium TA100, TA104, TA4001, and TA4006 |
| title_full_unstemmed | Base‐pair mutations caused by six aliphatic epoxides in salmonella typhimurium TA100, TA104, TA4001, and TA4006 |
| title_short | Base‐pair mutations caused by six aliphatic epoxides in salmonella typhimurium TA100, TA104, TA4001, and TA4006 |
| title_sort | base‐pair mutations caused by six aliphatic epoxides in salmonella typhimurium ta100, ta104, ta4001, and ta4006 |
| title_unstemmed | Base‐pair mutations caused by six aliphatic epoxides in salmonella typhimurium TA100, TA104, TA4001, and TA4006 |
| topic | Health, Toxicology and Mutagenesis, Genetics (clinical), Epidemiology |
| url | http://dx.doi.org/10.1002/em.2850210308 |