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Influence of the major histocompatibility comp(MHC) on the response to and expression of H‐Y in rats
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Zeitschriftentitel: | Developmental Genetics |
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Personen und Körperschaften: | , , |
In: | Developmental Genetics, 8, 1987, 4, S. 189-194 |
Format: | E-Article |
Sprache: | Englisch |
veröffentlicht: |
Wiley
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Schlagwörter: |
author_facet |
Desquenne‐Clark, Lise Chen, Hong‐Duo Silvers, Willys K. Desquenne‐Clark, Lise Chen, Hong‐Duo Silvers, Willys K. |
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author |
Desquenne‐Clark, Lise Chen, Hong‐Duo Silvers, Willys K. |
spellingShingle |
Desquenne‐Clark, Lise Chen, Hong‐Duo Silvers, Willys K. Developmental Genetics Influence of the major histocompatibility comp(MHC) on the response to and expression of H‐Y in rats Cell Biology Developmental Biology Genetics |
author_sort |
desquenne‐clark, lise |
spelling |
Desquenne‐Clark, Lise Chen, Hong‐Duo Silvers, Willys K. 0192-253X 1520-6408 Wiley Cell Biology Developmental Biology Genetics http://dx.doi.org/10.1002/dvg.1020080403 <jats:title>Abstract</jats:title><jats:p>The influence of the major histocompatibility complex (MHC) on the survival of H‐Y‐incompatible skin grafts in rats has been determined by challenging normal and previously sensitized females of various isogenic and congenic strains with male trunk or ear skin isografts. The MHC's influence on the potency of H‐Y has also been evaluated by determining the survival of male parental strain ear skin grafts on sensitized (with F<jats:sub>1</jats:sub> hybrid male cells) F<jats:sub>1</jats:sub> hybrid females of two different MHC congenic strains. The results indicate that, as in mice, the MHC has a dual affect on H‐Y; it is involved in determining the ability of females to respond to the antigen as well as influencing its potency.</jats:p> Influence of the major histocompatibility comp(MHC) on the response to and expression of H‐Y in rats Developmental Genetics |
doi_str_mv |
10.1002/dvg.1020080403 |
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Online |
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Biologie |
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Wiley, 1987 |
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Wiley, 1987 |
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1987 |
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Wiley |
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Developmental Genetics |
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49 |
title |
Influence of the major histocompatibility comp(MHC) on the response to and expression of H‐Y in rats |
title_unstemmed |
Influence of the major histocompatibility comp(MHC) on the response to and expression of H‐Y in rats |
title_full |
Influence of the major histocompatibility comp(MHC) on the response to and expression of H‐Y in rats |
title_fullStr |
Influence of the major histocompatibility comp(MHC) on the response to and expression of H‐Y in rats |
title_full_unstemmed |
Influence of the major histocompatibility comp(MHC) on the response to and expression of H‐Y in rats |
title_short |
Influence of the major histocompatibility comp(MHC) on the response to and expression of H‐Y in rats |
title_sort |
influence of the major histocompatibility comp(mhc) on the response to and expression of h‐y in rats |
topic |
Cell Biology Developmental Biology Genetics |
url |
http://dx.doi.org/10.1002/dvg.1020080403 |
publishDate |
1987 |
physical |
189-194 |
description |
<jats:title>Abstract</jats:title><jats:p>The influence of the major histocompatibility complex (MHC) on the survival of H‐Y‐incompatible skin grafts in rats has been determined by challenging normal and previously sensitized females of various isogenic and congenic strains with male trunk or ear skin isografts. The MHC's influence on the potency of H‐Y has also been evaluated by determining the survival of male parental strain ear skin grafts on sensitized (with F<jats:sub>1</jats:sub> hybrid male cells) F<jats:sub>1</jats:sub> hybrid females of two different MHC congenic strains. The results indicate that, as in mice, the MHC has a dual affect on H‐Y; it is involved in determining the ability of females to respond to the antigen as well as influencing its potency.</jats:p> |
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author | Desquenne‐Clark, Lise, Chen, Hong‐Duo, Silvers, Willys K. |
author_facet | Desquenne‐Clark, Lise, Chen, Hong‐Duo, Silvers, Willys K., Desquenne‐Clark, Lise, Chen, Hong‐Duo, Silvers, Willys K. |
author_sort | desquenne‐clark, lise |
container_issue | 4 |
container_start_page | 189 |
container_title | Developmental Genetics |
container_volume | 8 |
description | <jats:title>Abstract</jats:title><jats:p>The influence of the major histocompatibility complex (MHC) on the survival of H‐Y‐incompatible skin grafts in rats has been determined by challenging normal and previously sensitized females of various isogenic and congenic strains with male trunk or ear skin isografts. The MHC's influence on the potency of H‐Y has also been evaluated by determining the survival of male parental strain ear skin grafts on sensitized (with F<jats:sub>1</jats:sub> hybrid male cells) F<jats:sub>1</jats:sub> hybrid females of two different MHC congenic strains. The results indicate that, as in mice, the MHC has a dual affect on H‐Y; it is involved in determining the ability of females to respond to the antigen as well as influencing its potency.</jats:p> |
doi_str_mv | 10.1002/dvg.1020080403 |
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imprint | Wiley, 1987 |
imprint_str_mv | Wiley, 1987 |
institution | DE-Brt1, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1, DE-L229, DE-D275, DE-Bn3 |
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mega_collection | Wiley (CrossRef) |
physical | 189-194 |
publishDate | 1987 |
publishDateSort | 1987 |
publisher | Wiley |
record_format | ai |
recordtype | ai |
series | Developmental Genetics |
source_id | 49 |
spelling | Desquenne‐Clark, Lise Chen, Hong‐Duo Silvers, Willys K. 0192-253X 1520-6408 Wiley Cell Biology Developmental Biology Genetics http://dx.doi.org/10.1002/dvg.1020080403 <jats:title>Abstract</jats:title><jats:p>The influence of the major histocompatibility complex (MHC) on the survival of H‐Y‐incompatible skin grafts in rats has been determined by challenging normal and previously sensitized females of various isogenic and congenic strains with male trunk or ear skin isografts. The MHC's influence on the potency of H‐Y has also been evaluated by determining the survival of male parental strain ear skin grafts on sensitized (with F<jats:sub>1</jats:sub> hybrid male cells) F<jats:sub>1</jats:sub> hybrid females of two different MHC congenic strains. The results indicate that, as in mice, the MHC has a dual affect on H‐Y; it is involved in determining the ability of females to respond to the antigen as well as influencing its potency.</jats:p> Influence of the major histocompatibility comp(MHC) on the response to and expression of H‐Y in rats Developmental Genetics |
spellingShingle | Desquenne‐Clark, Lise, Chen, Hong‐Duo, Silvers, Willys K., Developmental Genetics, Influence of the major histocompatibility comp(MHC) on the response to and expression of H‐Y in rats, Cell Biology, Developmental Biology, Genetics |
title | Influence of the major histocompatibility comp(MHC) on the response to and expression of H‐Y in rats |
title_full | Influence of the major histocompatibility comp(MHC) on the response to and expression of H‐Y in rats |
title_fullStr | Influence of the major histocompatibility comp(MHC) on the response to and expression of H‐Y in rats |
title_full_unstemmed | Influence of the major histocompatibility comp(MHC) on the response to and expression of H‐Y in rats |
title_short | Influence of the major histocompatibility comp(MHC) on the response to and expression of H‐Y in rats |
title_sort | influence of the major histocompatibility comp(mhc) on the response to and expression of h‐y in rats |
title_unstemmed | Influence of the major histocompatibility comp(MHC) on the response to and expression of H‐Y in rats |
topic | Cell Biology, Developmental Biology, Genetics |
url | http://dx.doi.org/10.1002/dvg.1020080403 |