Eintrag weiter verarbeiten
Improvement in survival of patients with oral cavity squamous cell carcinoma: An international collaborative study
Gespeichert in:
| Zeitschriftentitel: | Cancer |
|---|---|
| Personen und Körperschaften: | , , , , , , , , , , , , , , , |
| In: | Cancer, 119, 2013, 24, S. 4242-4248 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Wiley
|
| Schlagwörter: |
| author_facet |
Amit, Moran Yen, Tzu‐Chen Liao, Chun‐Ta Chaturvedi, Pankaj Agarwal, Jai Prakash Kowalski, Luiz P. Ebrahimi, Ardalan Clark, Jonathan R. Kreppel, Matthias Zöller, Joachim Fridman, Eran Bolzoni, Villaret A. Shah, Jatin P. Binenbaum, Yoav Patel, Snehal G. Gil, Ziv Amit, Moran Yen, Tzu‐Chen Liao, Chun‐Ta Chaturvedi, Pankaj Agarwal, Jai Prakash Kowalski, Luiz P. Ebrahimi, Ardalan Clark, Jonathan R. Kreppel, Matthias Zöller, Joachim Fridman, Eran Bolzoni, Villaret A. Shah, Jatin P. Binenbaum, Yoav Patel, Snehal G. Gil, Ziv |
|---|---|
| author |
Amit, Moran Yen, Tzu‐Chen Liao, Chun‐Ta Chaturvedi, Pankaj Agarwal, Jai Prakash Kowalski, Luiz P. Ebrahimi, Ardalan Clark, Jonathan R. Kreppel, Matthias Zöller, Joachim Fridman, Eran Bolzoni, Villaret A. Shah, Jatin P. Binenbaum, Yoav Patel, Snehal G. Gil, Ziv |
| spellingShingle |
Amit, Moran Yen, Tzu‐Chen Liao, Chun‐Ta Chaturvedi, Pankaj Agarwal, Jai Prakash Kowalski, Luiz P. Ebrahimi, Ardalan Clark, Jonathan R. Kreppel, Matthias Zöller, Joachim Fridman, Eran Bolzoni, Villaret A. Shah, Jatin P. Binenbaum, Yoav Patel, Snehal G. Gil, Ziv Cancer Improvement in survival of patients with oral cavity squamous cell carcinoma: An international collaborative study Cancer Research Oncology |
| author_sort |
amit, moran |
| spelling |
Amit, Moran Yen, Tzu‐Chen Liao, Chun‐Ta Chaturvedi, Pankaj Agarwal, Jai Prakash Kowalski, Luiz P. Ebrahimi, Ardalan Clark, Jonathan R. Kreppel, Matthias Zöller, Joachim Fridman, Eran Bolzoni, Villaret A. Shah, Jatin P. Binenbaum, Yoav Patel, Snehal G. Gil, Ziv 0008-543X 1097-0142 Wiley Cancer Research Oncology http://dx.doi.org/10.1002/cncr.28357 <jats:sec><jats:title>BACKGROUND</jats:title><jats:p>An association between the survival of patients with oral cavity squamous cell carcinoma (OCSCC) and advancements in diagnosis and therapy has not been established.</jats:p></jats:sec><jats:sec><jats:title>METHODS</jats:title><jats:p>This was a retrospective, longitudinal, international, population‐based study of 2738 patients who underwent resection of OCSCC during 2 different decades. Characteristics of patients from 7 international cancer centers who received treatment between 1990 and 2000 (group A; n = 735) were compared with patients who received treatment between 2001 and 2011 (group B; n = 2003).</jats:p></jats:sec><jats:sec><jats:title>RESULTS</jats:title><jats:p>Patients in group B had more advanced tumors and tended to develop distant metastases more frequently than patients in group A (<jats:italic>P</jats:italic> = .005). More group B patients underwent selective neck dissection and received adjuvant radiotherapy (<jats:italic>P</jats:italic> < .001). Outcome analysis revealed a significant improvement in 5‐year overall survival, from 59% for group A to 70% for group B (<jats:italic>P</jats:italic> < .001). There was also a significant improvement in disease‐specific survival associated with operations performed before and after 2000 (from 69% to 81%, respectively; <jats:italic>P</jats:italic> < .001). Surgery after 2000, negative margins, adjuvant treatment, and early stage disease were independent predictors of a better outcome in multivariate analysis. The decade of treatment was an independent prognostic factor for cancer‐specific mortality (hazard ratio, 0.42; 95% confidence interval, 0.3‐0.6).</jats:p></jats:sec><jats:sec><jats:title>CONCLUSIONS</jats:title><jats:p>The survival rate of patients with OCSCC improved significantly during the past 2 decades despite older age, more advanced disease stage, and a higher rate of distant metastases. The current results suggest that the prognosis for patients with OCSCC has improved over time, presumably because of advances in imaging and therapy. <jats:bold><jats:italic>Cancer</jats:italic> 2013;119:4242–4248</jats:bold>. © <jats:italic>2013 American Cancer Society</jats:italic>.</jats:p></jats:sec> Improvement in survival of patients with oral cavity squamous cell carcinoma: An international collaborative study Cancer |
| doi_str_mv |
10.1002/cncr.28357 |
| facet_avail |
Online Free |
| finc_class_facet |
Medizin |
| format |
ElectronicArticle |
| fullrecord |
blob:ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAwMi9jbmNyLjI4MzU3 |
| id |
ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAwMi9jbmNyLjI4MzU3 |
| institution |
DE-D275 DE-Bn3 DE-Brt1 DE-Zwi2 DE-D161 DE-Zi4 DE-Gla1 DE-15 DE-Pl11 DE-Rs1 DE-14 DE-105 DE-Ch1 DE-L229 |
| imprint |
Wiley, 2013 |
| imprint_str_mv |
Wiley, 2013 |
| issn |
0008-543X 1097-0142 |
| issn_str_mv |
0008-543X 1097-0142 |
| language |
English |
| mega_collection |
Wiley (CrossRef) |
| match_str |
amit2013improvementinsurvivalofpatientswithoralcavitysquamouscellcarcinomaaninternationalcollaborativestudy |
| publishDateSort |
2013 |
| publisher |
Wiley |
| recordtype |
ai |
| record_format |
ai |
| series |
Cancer |
| source_id |
49 |
| title |
Improvement in survival of patients with oral cavity squamous cell carcinoma: An international collaborative study |
| title_unstemmed |
Improvement in survival of patients with oral cavity squamous cell carcinoma: An international collaborative study |
| title_full |
Improvement in survival of patients with oral cavity squamous cell carcinoma: An international collaborative study |
| title_fullStr |
Improvement in survival of patients with oral cavity squamous cell carcinoma: An international collaborative study |
| title_full_unstemmed |
Improvement in survival of patients with oral cavity squamous cell carcinoma: An international collaborative study |
| title_short |
Improvement in survival of patients with oral cavity squamous cell carcinoma: An international collaborative study |
| title_sort |
improvement in survival of patients with oral cavity squamous cell carcinoma: an international collaborative study |
| topic |
Cancer Research Oncology |
| url |
http://dx.doi.org/10.1002/cncr.28357 |
| publishDate |
2013 |
| physical |
4242-4248 |
| description |
<jats:sec><jats:title>BACKGROUND</jats:title><jats:p>An association between the survival of patients with oral cavity squamous cell carcinoma (OCSCC) and advancements in diagnosis and therapy has not been established.</jats:p></jats:sec><jats:sec><jats:title>METHODS</jats:title><jats:p>This was a retrospective, longitudinal, international, population‐based study of 2738 patients who underwent resection of OCSCC during 2 different decades. Characteristics of patients from 7 international cancer centers who received treatment between 1990 and 2000 (group A; n = 735) were compared with patients who received treatment between 2001 and 2011 (group B; n = 2003).</jats:p></jats:sec><jats:sec><jats:title>RESULTS</jats:title><jats:p>Patients in group B had more advanced tumors and tended to develop distant metastases more frequently than patients in group A (<jats:italic>P</jats:italic> = .005). More group B patients underwent selective neck dissection and received adjuvant radiotherapy (<jats:italic>P</jats:italic> < .001). Outcome analysis revealed a significant improvement in 5‐year overall survival, from 59% for group A to 70% for group B (<jats:italic>P</jats:italic> < .001). There was also a significant improvement in disease‐specific survival associated with operations performed before and after 2000 (from 69% to 81%, respectively; <jats:italic>P</jats:italic> < .001). Surgery after 2000, negative margins, adjuvant treatment, and early stage disease were independent predictors of a better outcome in multivariate analysis. The decade of treatment was an independent prognostic factor for cancer‐specific mortality (hazard ratio, 0.42; 95% confidence interval, 0.3‐0.6).</jats:p></jats:sec><jats:sec><jats:title>CONCLUSIONS</jats:title><jats:p>The survival rate of patients with OCSCC improved significantly during the past 2 decades despite older age, more advanced disease stage, and a higher rate of distant metastases. The current results suggest that the prognosis for patients with OCSCC has improved over time, presumably because of advances in imaging and therapy. <jats:bold><jats:italic>Cancer</jats:italic> 2013;119:4242–4248</jats:bold>. © <jats:italic>2013 American Cancer Society</jats:italic>.</jats:p></jats:sec> |
| container_issue |
24 |
| container_start_page |
4242 |
| container_title |
Cancer |
| container_volume |
119 |
| format_de105 |
Article, E-Article |
| format_de14 |
Article, E-Article |
| format_de15 |
Article, E-Article |
| format_de520 |
Article, E-Article |
| format_de540 |
Article, E-Article |
| format_dech1 |
Article, E-Article |
| format_ded117 |
Article, E-Article |
| format_degla1 |
E-Article |
| format_del152 |
Buch |
| format_del189 |
Article, E-Article |
| format_dezi4 |
Article |
| format_dezwi2 |
Article, E-Article |
| format_finc |
Article, E-Article |
| format_nrw |
Article, E-Article |
| _version_ |
1792344335086256132 |
| geogr_code |
not assigned |
| last_indexed |
2024-03-01T17:05:56.382Z |
| geogr_code_person |
not assigned |
| openURL |
url_ver=Z39.88-2004&ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fvufind.svn.sourceforge.net%3Agenerator&rft.title=Improvement+in+survival+of+patients+with+oral+cavity+squamous+cell+carcinoma%3A+An+international+collaborative+study&rft.date=2013-12-15&genre=article&issn=1097-0142&volume=119&issue=24&spage=4242&epage=4248&pages=4242-4248&jtitle=Cancer&atitle=Improvement+in+survival+of+patients+with+oral+cavity+squamous+cell+carcinoma%3A+An+international+collaborative+study&aulast=Gil&aufirst=Ziv&rft_id=info%3Adoi%2F10.1002%2Fcncr.28357&rft.language%5B0%5D=eng |
| SOLR | |
| _version_ | 1792344335086256132 |
| author | Amit, Moran, Yen, Tzu‐Chen, Liao, Chun‐Ta, Chaturvedi, Pankaj, Agarwal, Jai Prakash, Kowalski, Luiz P., Ebrahimi, Ardalan, Clark, Jonathan R., Kreppel, Matthias, Zöller, Joachim, Fridman, Eran, Bolzoni, Villaret A., Shah, Jatin P., Binenbaum, Yoav, Patel, Snehal G., Gil, Ziv |
| author_facet | Amit, Moran, Yen, Tzu‐Chen, Liao, Chun‐Ta, Chaturvedi, Pankaj, Agarwal, Jai Prakash, Kowalski, Luiz P., Ebrahimi, Ardalan, Clark, Jonathan R., Kreppel, Matthias, Zöller, Joachim, Fridman, Eran, Bolzoni, Villaret A., Shah, Jatin P., Binenbaum, Yoav, Patel, Snehal G., Gil, Ziv, Amit, Moran, Yen, Tzu‐Chen, Liao, Chun‐Ta, Chaturvedi, Pankaj, Agarwal, Jai Prakash, Kowalski, Luiz P., Ebrahimi, Ardalan, Clark, Jonathan R., Kreppel, Matthias, Zöller, Joachim, Fridman, Eran, Bolzoni, Villaret A., Shah, Jatin P., Binenbaum, Yoav, Patel, Snehal G., Gil, Ziv |
| author_sort | amit, moran |
| container_issue | 24 |
| container_start_page | 4242 |
| container_title | Cancer |
| container_volume | 119 |
| description | <jats:sec><jats:title>BACKGROUND</jats:title><jats:p>An association between the survival of patients with oral cavity squamous cell carcinoma (OCSCC) and advancements in diagnosis and therapy has not been established.</jats:p></jats:sec><jats:sec><jats:title>METHODS</jats:title><jats:p>This was a retrospective, longitudinal, international, population‐based study of 2738 patients who underwent resection of OCSCC during 2 different decades. Characteristics of patients from 7 international cancer centers who received treatment between 1990 and 2000 (group A; n = 735) were compared with patients who received treatment between 2001 and 2011 (group B; n = 2003).</jats:p></jats:sec><jats:sec><jats:title>RESULTS</jats:title><jats:p>Patients in group B had more advanced tumors and tended to develop distant metastases more frequently than patients in group A (<jats:italic>P</jats:italic> = .005). More group B patients underwent selective neck dissection and received adjuvant radiotherapy (<jats:italic>P</jats:italic> < .001). Outcome analysis revealed a significant improvement in 5‐year overall survival, from 59% for group A to 70% for group B (<jats:italic>P</jats:italic> < .001). There was also a significant improvement in disease‐specific survival associated with operations performed before and after 2000 (from 69% to 81%, respectively; <jats:italic>P</jats:italic> < .001). Surgery after 2000, negative margins, adjuvant treatment, and early stage disease were independent predictors of a better outcome in multivariate analysis. The decade of treatment was an independent prognostic factor for cancer‐specific mortality (hazard ratio, 0.42; 95% confidence interval, 0.3‐0.6).</jats:p></jats:sec><jats:sec><jats:title>CONCLUSIONS</jats:title><jats:p>The survival rate of patients with OCSCC improved significantly during the past 2 decades despite older age, more advanced disease stage, and a higher rate of distant metastases. The current results suggest that the prognosis for patients with OCSCC has improved over time, presumably because of advances in imaging and therapy. <jats:bold><jats:italic>Cancer</jats:italic> 2013;119:4242–4248</jats:bold>. © <jats:italic>2013 American Cancer Society</jats:italic>.</jats:p></jats:sec> |
| doi_str_mv | 10.1002/cncr.28357 |
| facet_avail | Online, Free |
| finc_class_facet | Medizin |
| format | ElectronicArticle |
| format_de105 | Article, E-Article |
| format_de14 | Article, E-Article |
| format_de15 | Article, E-Article |
| format_de520 | Article, E-Article |
| format_de540 | Article, E-Article |
| format_dech1 | Article, E-Article |
| format_ded117 | Article, E-Article |
| format_degla1 | E-Article |
| format_del152 | Buch |
| format_del189 | Article, E-Article |
| format_dezi4 | Article |
| format_dezwi2 | Article, E-Article |
| format_finc | Article, E-Article |
| format_nrw | Article, E-Article |
| geogr_code | not assigned |
| geogr_code_person | not assigned |
| id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTAwMi9jbmNyLjI4MzU3 |
| imprint | Wiley, 2013 |
| imprint_str_mv | Wiley, 2013 |
| institution | DE-D275, DE-Bn3, DE-Brt1, DE-Zwi2, DE-D161, DE-Zi4, DE-Gla1, DE-15, DE-Pl11, DE-Rs1, DE-14, DE-105, DE-Ch1, DE-L229 |
| issn | 0008-543X, 1097-0142 |
| issn_str_mv | 0008-543X, 1097-0142 |
| language | English |
| last_indexed | 2024-03-01T17:05:56.382Z |
| match_str | amit2013improvementinsurvivalofpatientswithoralcavitysquamouscellcarcinomaaninternationalcollaborativestudy |
| mega_collection | Wiley (CrossRef) |
| physical | 4242-4248 |
| publishDate | 2013 |
| publishDateSort | 2013 |
| publisher | Wiley |
| record_format | ai |
| recordtype | ai |
| series | Cancer |
| source_id | 49 |
| spelling | Amit, Moran Yen, Tzu‐Chen Liao, Chun‐Ta Chaturvedi, Pankaj Agarwal, Jai Prakash Kowalski, Luiz P. Ebrahimi, Ardalan Clark, Jonathan R. Kreppel, Matthias Zöller, Joachim Fridman, Eran Bolzoni, Villaret A. Shah, Jatin P. Binenbaum, Yoav Patel, Snehal G. Gil, Ziv 0008-543X 1097-0142 Wiley Cancer Research Oncology http://dx.doi.org/10.1002/cncr.28357 <jats:sec><jats:title>BACKGROUND</jats:title><jats:p>An association between the survival of patients with oral cavity squamous cell carcinoma (OCSCC) and advancements in diagnosis and therapy has not been established.</jats:p></jats:sec><jats:sec><jats:title>METHODS</jats:title><jats:p>This was a retrospective, longitudinal, international, population‐based study of 2738 patients who underwent resection of OCSCC during 2 different decades. Characteristics of patients from 7 international cancer centers who received treatment between 1990 and 2000 (group A; n = 735) were compared with patients who received treatment between 2001 and 2011 (group B; n = 2003).</jats:p></jats:sec><jats:sec><jats:title>RESULTS</jats:title><jats:p>Patients in group B had more advanced tumors and tended to develop distant metastases more frequently than patients in group A (<jats:italic>P</jats:italic> = .005). More group B patients underwent selective neck dissection and received adjuvant radiotherapy (<jats:italic>P</jats:italic> < .001). Outcome analysis revealed a significant improvement in 5‐year overall survival, from 59% for group A to 70% for group B (<jats:italic>P</jats:italic> < .001). There was also a significant improvement in disease‐specific survival associated with operations performed before and after 2000 (from 69% to 81%, respectively; <jats:italic>P</jats:italic> < .001). Surgery after 2000, negative margins, adjuvant treatment, and early stage disease were independent predictors of a better outcome in multivariate analysis. The decade of treatment was an independent prognostic factor for cancer‐specific mortality (hazard ratio, 0.42; 95% confidence interval, 0.3‐0.6).</jats:p></jats:sec><jats:sec><jats:title>CONCLUSIONS</jats:title><jats:p>The survival rate of patients with OCSCC improved significantly during the past 2 decades despite older age, more advanced disease stage, and a higher rate of distant metastases. The current results suggest that the prognosis for patients with OCSCC has improved over time, presumably because of advances in imaging and therapy. <jats:bold><jats:italic>Cancer</jats:italic> 2013;119:4242–4248</jats:bold>. © <jats:italic>2013 American Cancer Society</jats:italic>.</jats:p></jats:sec> Improvement in survival of patients with oral cavity squamous cell carcinoma: An international collaborative study Cancer |
| spellingShingle | Amit, Moran, Yen, Tzu‐Chen, Liao, Chun‐Ta, Chaturvedi, Pankaj, Agarwal, Jai Prakash, Kowalski, Luiz P., Ebrahimi, Ardalan, Clark, Jonathan R., Kreppel, Matthias, Zöller, Joachim, Fridman, Eran, Bolzoni, Villaret A., Shah, Jatin P., Binenbaum, Yoav, Patel, Snehal G., Gil, Ziv, Cancer, Improvement in survival of patients with oral cavity squamous cell carcinoma: An international collaborative study, Cancer Research, Oncology |
| title | Improvement in survival of patients with oral cavity squamous cell carcinoma: An international collaborative study |
| title_full | Improvement in survival of patients with oral cavity squamous cell carcinoma: An international collaborative study |
| title_fullStr | Improvement in survival of patients with oral cavity squamous cell carcinoma: An international collaborative study |
| title_full_unstemmed | Improvement in survival of patients with oral cavity squamous cell carcinoma: An international collaborative study |
| title_short | Improvement in survival of patients with oral cavity squamous cell carcinoma: An international collaborative study |
| title_sort | improvement in survival of patients with oral cavity squamous cell carcinoma: an international collaborative study |
| title_unstemmed | Improvement in survival of patients with oral cavity squamous cell carcinoma: An international collaborative study |
| topic | Cancer Research, Oncology |
| url | http://dx.doi.org/10.1002/cncr.28357 |