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Cover Picture: On the Remarkable Antitumor Properties of Fludelone: How We Got There (Angew. Chem. Int. Ed. 19/2005)
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| Zeitschriftentitel: | Angewandte Chemie International Edition |
|---|---|
| Personen und Körperschaften: | , , |
| In: | Angewandte Chemie International Edition, 44, 2005, 19, S. 2817-2817 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Wiley
|
| Schlagwörter: |
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Rivkin, Alexey Chou, Ting‐Chao Danishefsky, Samuel J. Rivkin, Alexey Chou, Ting‐Chao Danishefsky, Samuel J. |
|---|---|
| author |
Rivkin, Alexey Chou, Ting‐Chao Danishefsky, Samuel J. |
| spellingShingle |
Rivkin, Alexey Chou, Ting‐Chao Danishefsky, Samuel J. Angewandte Chemie International Edition Cover Picture: On the Remarkable Antitumor Properties of Fludelone: How We Got There (Angew. Chem. Int. Ed. 19/2005) General Chemistry Catalysis |
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rivkin, alexey |
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Rivkin, Alexey Chou, Ting‐Chao Danishefsky, Samuel J. 1433-7851 1521-3773 Wiley General Chemistry Catalysis http://dx.doi.org/10.1002/anie.200590063 <jats:p><jats:bold>Synthetic and biological studies</jats:bold> of epothilone B (isolated from a myxobacterium) led to the discovery of a 26‐trifluoro analogue that is remarkably active in treating xenograft tumors in nude mice. These findings underscore the potential of using natural products as leads, in conjunction with directed total synthesis, in the quest for new drugs. S. J. Danishefsky and co‐workers present their synthetic strategy along with biological data in their Minireview on page 2838 ff.</jats:p> Cover Picture: On the Remarkable Antitumor Properties of Fludelone: How We Got There (Angew. Chem. Int. Ed. 19/2005) Angewandte Chemie International Edition |
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Cover Picture: On the Remarkable Antitumor Properties of Fludelone: How We Got There (Angew. Chem. Int. Ed. 19/2005) |
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Cover Picture: On the Remarkable Antitumor Properties of Fludelone: How We Got There (Angew. Chem. Int. Ed. 19/2005) |
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Cover Picture: On the Remarkable Antitumor Properties of Fludelone: How We Got There (Angew. Chem. Int. Ed. 19/2005) |
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Cover Picture: On the Remarkable Antitumor Properties of Fludelone: How We Got There (Angew. Chem. Int. Ed. 19/2005) |
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Cover Picture: On the Remarkable Antitumor Properties of Fludelone: How We Got There (Angew. Chem. Int. Ed. 19/2005) |
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Cover Picture: On the Remarkable Antitumor Properties of Fludelone: How We Got There (Angew. Chem. Int. Ed. 19/2005) |
| title_sort |
cover picture: on the remarkable antitumor properties of fludelone: how we got there (angew. chem. int. ed. 19/2005) |
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General Chemistry Catalysis |
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http://dx.doi.org/10.1002/anie.200590063 |
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2005 |
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2817-2817 |
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<jats:p><jats:bold>Synthetic and biological studies</jats:bold> of epothilone B (isolated from a myxobacterium) led to the discovery of a 26‐trifluoro analogue that is remarkably active in treating xenograft tumors in nude mice. These findings underscore the potential of using natural products as leads, in conjunction with directed total synthesis, in the quest for new drugs. S. J. Danishefsky and co‐workers present their synthetic strategy along with biological data in their Minireview on page 2838 ff.</jats:p> |
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| author | Rivkin, Alexey, Chou, Ting‐Chao, Danishefsky, Samuel J. |
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| description | <jats:p><jats:bold>Synthetic and biological studies</jats:bold> of epothilone B (isolated from a myxobacterium) led to the discovery of a 26‐trifluoro analogue that is remarkably active in treating xenograft tumors in nude mice. These findings underscore the potential of using natural products as leads, in conjunction with directed total synthesis, in the quest for new drugs. S. J. Danishefsky and co‐workers present their synthetic strategy along with biological data in their Minireview on page 2838 ff.</jats:p> |
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| spelling | Rivkin, Alexey Chou, Ting‐Chao Danishefsky, Samuel J. 1433-7851 1521-3773 Wiley General Chemistry Catalysis http://dx.doi.org/10.1002/anie.200590063 <jats:p><jats:bold>Synthetic and biological studies</jats:bold> of epothilone B (isolated from a myxobacterium) led to the discovery of a 26‐trifluoro analogue that is remarkably active in treating xenograft tumors in nude mice. These findings underscore the potential of using natural products as leads, in conjunction with directed total synthesis, in the quest for new drugs. S. J. Danishefsky and co‐workers present their synthetic strategy along with biological data in their Minireview on page 2838 ff.</jats:p> Cover Picture: On the Remarkable Antitumor Properties of Fludelone: How We Got There (Angew. Chem. Int. Ed. 19/2005) Angewandte Chemie International Edition |
| spellingShingle | Rivkin, Alexey, Chou, Ting‐Chao, Danishefsky, Samuel J., Angewandte Chemie International Edition, Cover Picture: On the Remarkable Antitumor Properties of Fludelone: How We Got There (Angew. Chem. Int. Ed. 19/2005), General Chemistry, Catalysis |
| title | Cover Picture: On the Remarkable Antitumor Properties of Fludelone: How We Got There (Angew. Chem. Int. Ed. 19/2005) |
| title_full | Cover Picture: On the Remarkable Antitumor Properties of Fludelone: How We Got There (Angew. Chem. Int. Ed. 19/2005) |
| title_fullStr | Cover Picture: On the Remarkable Antitumor Properties of Fludelone: How We Got There (Angew. Chem. Int. Ed. 19/2005) |
| title_full_unstemmed | Cover Picture: On the Remarkable Antitumor Properties of Fludelone: How We Got There (Angew. Chem. Int. Ed. 19/2005) |
| title_short | Cover Picture: On the Remarkable Antitumor Properties of Fludelone: How We Got There (Angew. Chem. Int. Ed. 19/2005) |
| title_sort | cover picture: on the remarkable antitumor properties of fludelone: how we got there (angew. chem. int. ed. 19/2005) |
| title_unstemmed | Cover Picture: On the Remarkable Antitumor Properties of Fludelone: How We Got There (Angew. Chem. Int. Ed. 19/2005) |
| topic | General Chemistry, Catalysis |
| url | http://dx.doi.org/10.1002/anie.200590063 |