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Comparison of multiparametric MRI‐based and transrectal ultrasound‐based preplans with intraoperative ultrasound‐based planning for low dose rate interstitial prostate seed implant...
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| Zeitschriftentitel: | Journal of Applied Clinical Medical Physics |
|---|---|
| Personen und Körperschaften: | , , , , , , , |
| In: | Journal of Applied Clinical Medical Physics, 20, 2019, 6, S. 31-38 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Wiley
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| Schlagwörter: |
| author_facet |
Fredman, Elisha T. Traughber, Bryan J. Gross, Andrew Podder, Tarun Colussi, Valdir Vinkler, Robert Machtay, Mitchell Ellis, Rodney J. Fredman, Elisha T. Traughber, Bryan J. Gross, Andrew Podder, Tarun Colussi, Valdir Vinkler, Robert Machtay, Mitchell Ellis, Rodney J. |
|---|---|
| author |
Fredman, Elisha T. Traughber, Bryan J. Gross, Andrew Podder, Tarun Colussi, Valdir Vinkler, Robert Machtay, Mitchell Ellis, Rodney J. |
| spellingShingle |
Fredman, Elisha T. Traughber, Bryan J. Gross, Andrew Podder, Tarun Colussi, Valdir Vinkler, Robert Machtay, Mitchell Ellis, Rodney J. Journal of Applied Clinical Medical Physics Comparison of multiparametric MRI‐based and transrectal ultrasound‐based preplans with intraoperative ultrasound‐based planning for low dose rate interstitial prostate seed implantation Radiology, Nuclear Medicine and imaging Instrumentation Radiation |
| author_sort |
fredman, elisha t. |
| spelling |
Fredman, Elisha T. Traughber, Bryan J. Gross, Andrew Podder, Tarun Colussi, Valdir Vinkler, Robert Machtay, Mitchell Ellis, Rodney J. 1526-9914 1526-9914 Wiley Radiology, Nuclear Medicine and imaging Instrumentation Radiation http://dx.doi.org/10.1002/acm2.12592 <jats:title>Abstract</jats:title><jats:sec><jats:title>Purpose</jats:title><jats:p>Transrectal ultrasound images are routinely acquired for low dose rate (<jats:styled-content style="fixed-case">LDR</jats:styled-content>) prostate brachytherapy dosimetric preplanning (<jats:styled-content style="fixed-case">pTRUS</jats:styled-content>), although diagnostic multiparametric magnetic resonance imaging (mp<jats:styled-content style="fixed-case">MRI</jats:styled-content>) may serve this purpose as well. We compared the predictive abilities of <jats:styled-content style="fixed-case">TRUS</jats:styled-content> vs <jats:styled-content style="fixed-case">MRI</jats:styled-content> relative to intraoperative <jats:styled-content style="fixed-case">TRUS</jats:styled-content> (<jats:styled-content style="fixed-case">iTRUS</jats:styled-content>) to assess the role of mp<jats:styled-content style="fixed-case">MRI</jats:styled-content> in brachytherapy preplanning.</jats:p></jats:sec><jats:sec><jats:title>Materials and methods</jats:title><jats:p>Retrospective analysis was performed on 32 patients who underwent <jats:styled-content style="fixed-case">iTRUS</jats:styled-content>‐guided prostate <jats:styled-content style="fixed-case">LDR</jats:styled-content> brachytherapy as either mono‐ or combination therapy. 56.3% had <jats:styled-content style="fixed-case">pTRUS</jats:styled-content>‐only volume studies and 43.7% had both 3T‐mp<jats:styled-content style="fixed-case">MRI</jats:styled-content> and <jats:styled-content style="fixed-case">pTRUS</jats:styled-content> preplanning. <jats:styled-content style="fixed-case">MRI</jats:styled-content> was used for preplanning and its image fusion with <jats:styled-content style="fixed-case">iTRUS</jats:styled-content> was also used for intraoperative guidance of seed placement. Differences in gland volume, seed number, and activity and procedure time were examined, as well as the identification of lesions suspicious for tumor foci. Pearson correlation coefficient and Fisher's Z test were used to estimate associations between continuous measures.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>There was good correlation of planning volumes between <jats:styled-content style="fixed-case">iTRUS</jats:styled-content> and either <jats:styled-content style="fixed-case">pTRUS</jats:styled-content> or <jats:styled-content style="fixed-case">MRI</jats:styled-content> (<jats:italic>r</jats:italic> = 0.89, <jats:italic>r</jats:italic> = 0.77), not impacted by the addition of hormonal therapy (<jats:italic>P</jats:italic> = 0.65, <jats:italic>P</jats:italic> = 0.33). Both consistently predicted intraoperative seed number (<jats:italic>r</jats:italic> = 0.87, <jats:italic>r</jats:italic> = 0.86). <jats:styled-content style="fixed-case">MRI</jats:styled-content>/<jats:styled-content style="fixed-case">TRUS</jats:styled-content> fusion did not significantly increase surgical or anesthesia time (<jats:italic>P</jats:italic> = 0.10, <jats:italic>P</jats:italic> = 0.46). mp<jats:styled-content style="fixed-case">MRI</jats:styled-content> revealed suspicious focal lesions in 11 of 14 cases not visible on <jats:styled-content style="fixed-case">pTRUS</jats:styled-content>, that when correlated with histopathology, were incorporated into the plan.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Relative to <jats:styled-content style="fixed-case">pTRUS</jats:styled-content>,<jats:styled-content style="fixed-case"> MRI</jats:styled-content> yielded reliable preplanning measures, supporting the role of <jats:styled-content style="fixed-case">MRI</jats:styled-content>‐only <jats:styled-content style="fixed-case">LDR</jats:styled-content> treatment planning. mp<jats:styled-content style="fixed-case">MRI</jats:styled-content> carries numerous diagnostic, staging and preplanning advantages that facilitate better patient selection and delivery of novel dose escalation and targeted therapy, with no additional surgical or anesthesia time. Prospective studies assessing its impact on treatment planning and delivery can serve to establish mp<jats:styled-content style="fixed-case">MRI</jats:styled-content> as the standard of care in <jats:styled-content style="fixed-case">LDR</jats:styled-content> prostate brachytherapy planning.</jats:p></jats:sec> Comparison of multiparametric <scp>MRI</scp>‐based and transrectal ultrasound‐based preplans with intraoperative ultrasound‐based planning for low dose rate interstitial prostate seed implantation Journal of Applied Clinical Medical Physics |
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Wiley, 2019 |
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Wiley, 2019 |
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fredman2019comparisonofmultiparametricmribasedandtransrectalultrasoundbasedpreplanswithintraoperativeultrasoundbasedplanningforlowdoserateinterstitialprostateseedimplantation |
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2019 |
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Wiley |
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Journal of Applied Clinical Medical Physics |
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49 |
| title |
Comparison of multiparametric MRI‐based and transrectal ultrasound‐based preplans with intraoperative ultrasound‐based planning for low dose rate interstitial prostate seed implantation |
| title_unstemmed |
Comparison of multiparametric MRI‐based and transrectal ultrasound‐based preplans with intraoperative ultrasound‐based planning for low dose rate interstitial prostate seed implantation |
| title_full |
Comparison of multiparametric MRI‐based and transrectal ultrasound‐based preplans with intraoperative ultrasound‐based planning for low dose rate interstitial prostate seed implantation |
| title_fullStr |
Comparison of multiparametric MRI‐based and transrectal ultrasound‐based preplans with intraoperative ultrasound‐based planning for low dose rate interstitial prostate seed implantation |
| title_full_unstemmed |
Comparison of multiparametric MRI‐based and transrectal ultrasound‐based preplans with intraoperative ultrasound‐based planning for low dose rate interstitial prostate seed implantation |
| title_short |
Comparison of multiparametric MRI‐based and transrectal ultrasound‐based preplans with intraoperative ultrasound‐based planning for low dose rate interstitial prostate seed implantation |
| title_sort |
comparison of multiparametric <scp>mri</scp>‐based and transrectal ultrasound‐based preplans with intraoperative ultrasound‐based planning for low dose rate interstitial prostate seed implantation |
| topic |
Radiology, Nuclear Medicine and imaging Instrumentation Radiation |
| url |
http://dx.doi.org/10.1002/acm2.12592 |
| publishDate |
2019 |
| physical |
31-38 |
| description |
<jats:title>Abstract</jats:title><jats:sec><jats:title>Purpose</jats:title><jats:p>Transrectal ultrasound images are routinely acquired for low dose rate (<jats:styled-content style="fixed-case">LDR</jats:styled-content>) prostate brachytherapy dosimetric preplanning (<jats:styled-content style="fixed-case">pTRUS</jats:styled-content>), although diagnostic multiparametric magnetic resonance imaging (mp<jats:styled-content style="fixed-case">MRI</jats:styled-content>) may serve this purpose as well. We compared the predictive abilities of <jats:styled-content style="fixed-case">TRUS</jats:styled-content> vs <jats:styled-content style="fixed-case">MRI</jats:styled-content> relative to intraoperative <jats:styled-content style="fixed-case">TRUS</jats:styled-content> (<jats:styled-content style="fixed-case">iTRUS</jats:styled-content>) to assess the role of mp<jats:styled-content style="fixed-case">MRI</jats:styled-content> in brachytherapy preplanning.</jats:p></jats:sec><jats:sec><jats:title>Materials and methods</jats:title><jats:p>Retrospective analysis was performed on 32 patients who underwent <jats:styled-content style="fixed-case">iTRUS</jats:styled-content>‐guided prostate <jats:styled-content style="fixed-case">LDR</jats:styled-content> brachytherapy as either mono‐ or combination therapy. 56.3% had <jats:styled-content style="fixed-case">pTRUS</jats:styled-content>‐only volume studies and 43.7% had both 3T‐mp<jats:styled-content style="fixed-case">MRI</jats:styled-content> and <jats:styled-content style="fixed-case">pTRUS</jats:styled-content> preplanning. <jats:styled-content style="fixed-case">MRI</jats:styled-content> was used for preplanning and its image fusion with <jats:styled-content style="fixed-case">iTRUS</jats:styled-content> was also used for intraoperative guidance of seed placement. Differences in gland volume, seed number, and activity and procedure time were examined, as well as the identification of lesions suspicious for tumor foci. Pearson correlation coefficient and Fisher's Z test were used to estimate associations between continuous measures.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>There was good correlation of planning volumes between <jats:styled-content style="fixed-case">iTRUS</jats:styled-content> and either <jats:styled-content style="fixed-case">pTRUS</jats:styled-content> or <jats:styled-content style="fixed-case">MRI</jats:styled-content> (<jats:italic>r</jats:italic> = 0.89, <jats:italic>r</jats:italic> = 0.77), not impacted by the addition of hormonal therapy (<jats:italic>P</jats:italic> = 0.65, <jats:italic>P</jats:italic> = 0.33). Both consistently predicted intraoperative seed number (<jats:italic>r</jats:italic> = 0.87, <jats:italic>r</jats:italic> = 0.86). <jats:styled-content style="fixed-case">MRI</jats:styled-content>/<jats:styled-content style="fixed-case">TRUS</jats:styled-content> fusion did not significantly increase surgical or anesthesia time (<jats:italic>P</jats:italic> = 0.10, <jats:italic>P</jats:italic> = 0.46). mp<jats:styled-content style="fixed-case">MRI</jats:styled-content> revealed suspicious focal lesions in 11 of 14 cases not visible on <jats:styled-content style="fixed-case">pTRUS</jats:styled-content>, that when correlated with histopathology, were incorporated into the plan.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Relative to <jats:styled-content style="fixed-case">pTRUS</jats:styled-content>,<jats:styled-content style="fixed-case"> MRI</jats:styled-content> yielded reliable preplanning measures, supporting the role of <jats:styled-content style="fixed-case">MRI</jats:styled-content>‐only <jats:styled-content style="fixed-case">LDR</jats:styled-content> treatment planning. mp<jats:styled-content style="fixed-case">MRI</jats:styled-content> carries numerous diagnostic, staging and preplanning advantages that facilitate better patient selection and delivery of novel dose escalation and targeted therapy, with no additional surgical or anesthesia time. Prospective studies assessing its impact on treatment planning and delivery can serve to establish mp<jats:styled-content style="fixed-case">MRI</jats:styled-content> as the standard of care in <jats:styled-content style="fixed-case">LDR</jats:styled-content> prostate brachytherapy planning.</jats:p></jats:sec> |
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| author | Fredman, Elisha T., Traughber, Bryan J., Gross, Andrew, Podder, Tarun, Colussi, Valdir, Vinkler, Robert, Machtay, Mitchell, Ellis, Rodney J. |
| author_facet | Fredman, Elisha T., Traughber, Bryan J., Gross, Andrew, Podder, Tarun, Colussi, Valdir, Vinkler, Robert, Machtay, Mitchell, Ellis, Rodney J., Fredman, Elisha T., Traughber, Bryan J., Gross, Andrew, Podder, Tarun, Colussi, Valdir, Vinkler, Robert, Machtay, Mitchell, Ellis, Rodney J. |
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| description | <jats:title>Abstract</jats:title><jats:sec><jats:title>Purpose</jats:title><jats:p>Transrectal ultrasound images are routinely acquired for low dose rate (<jats:styled-content style="fixed-case">LDR</jats:styled-content>) prostate brachytherapy dosimetric preplanning (<jats:styled-content style="fixed-case">pTRUS</jats:styled-content>), although diagnostic multiparametric magnetic resonance imaging (mp<jats:styled-content style="fixed-case">MRI</jats:styled-content>) may serve this purpose as well. We compared the predictive abilities of <jats:styled-content style="fixed-case">TRUS</jats:styled-content> vs <jats:styled-content style="fixed-case">MRI</jats:styled-content> relative to intraoperative <jats:styled-content style="fixed-case">TRUS</jats:styled-content> (<jats:styled-content style="fixed-case">iTRUS</jats:styled-content>) to assess the role of mp<jats:styled-content style="fixed-case">MRI</jats:styled-content> in brachytherapy preplanning.</jats:p></jats:sec><jats:sec><jats:title>Materials and methods</jats:title><jats:p>Retrospective analysis was performed on 32 patients who underwent <jats:styled-content style="fixed-case">iTRUS</jats:styled-content>‐guided prostate <jats:styled-content style="fixed-case">LDR</jats:styled-content> brachytherapy as either mono‐ or combination therapy. 56.3% had <jats:styled-content style="fixed-case">pTRUS</jats:styled-content>‐only volume studies and 43.7% had both 3T‐mp<jats:styled-content style="fixed-case">MRI</jats:styled-content> and <jats:styled-content style="fixed-case">pTRUS</jats:styled-content> preplanning. <jats:styled-content style="fixed-case">MRI</jats:styled-content> was used for preplanning and its image fusion with <jats:styled-content style="fixed-case">iTRUS</jats:styled-content> was also used for intraoperative guidance of seed placement. Differences in gland volume, seed number, and activity and procedure time were examined, as well as the identification of lesions suspicious for tumor foci. Pearson correlation coefficient and Fisher's Z test were used to estimate associations between continuous measures.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>There was good correlation of planning volumes between <jats:styled-content style="fixed-case">iTRUS</jats:styled-content> and either <jats:styled-content style="fixed-case">pTRUS</jats:styled-content> or <jats:styled-content style="fixed-case">MRI</jats:styled-content> (<jats:italic>r</jats:italic> = 0.89, <jats:italic>r</jats:italic> = 0.77), not impacted by the addition of hormonal therapy (<jats:italic>P</jats:italic> = 0.65, <jats:italic>P</jats:italic> = 0.33). Both consistently predicted intraoperative seed number (<jats:italic>r</jats:italic> = 0.87, <jats:italic>r</jats:italic> = 0.86). <jats:styled-content style="fixed-case">MRI</jats:styled-content>/<jats:styled-content style="fixed-case">TRUS</jats:styled-content> fusion did not significantly increase surgical or anesthesia time (<jats:italic>P</jats:italic> = 0.10, <jats:italic>P</jats:italic> = 0.46). mp<jats:styled-content style="fixed-case">MRI</jats:styled-content> revealed suspicious focal lesions in 11 of 14 cases not visible on <jats:styled-content style="fixed-case">pTRUS</jats:styled-content>, that when correlated with histopathology, were incorporated into the plan.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Relative to <jats:styled-content style="fixed-case">pTRUS</jats:styled-content>,<jats:styled-content style="fixed-case"> MRI</jats:styled-content> yielded reliable preplanning measures, supporting the role of <jats:styled-content style="fixed-case">MRI</jats:styled-content>‐only <jats:styled-content style="fixed-case">LDR</jats:styled-content> treatment planning. mp<jats:styled-content style="fixed-case">MRI</jats:styled-content> carries numerous diagnostic, staging and preplanning advantages that facilitate better patient selection and delivery of novel dose escalation and targeted therapy, with no additional surgical or anesthesia time. Prospective studies assessing its impact on treatment planning and delivery can serve to establish mp<jats:styled-content style="fixed-case">MRI</jats:styled-content> as the standard of care in <jats:styled-content style="fixed-case">LDR</jats:styled-content> prostate brachytherapy planning.</jats:p></jats:sec> |
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| series | Journal of Applied Clinical Medical Physics |
| source_id | 49 |
| spelling | Fredman, Elisha T. Traughber, Bryan J. Gross, Andrew Podder, Tarun Colussi, Valdir Vinkler, Robert Machtay, Mitchell Ellis, Rodney J. 1526-9914 1526-9914 Wiley Radiology, Nuclear Medicine and imaging Instrumentation Radiation http://dx.doi.org/10.1002/acm2.12592 <jats:title>Abstract</jats:title><jats:sec><jats:title>Purpose</jats:title><jats:p>Transrectal ultrasound images are routinely acquired for low dose rate (<jats:styled-content style="fixed-case">LDR</jats:styled-content>) prostate brachytherapy dosimetric preplanning (<jats:styled-content style="fixed-case">pTRUS</jats:styled-content>), although diagnostic multiparametric magnetic resonance imaging (mp<jats:styled-content style="fixed-case">MRI</jats:styled-content>) may serve this purpose as well. We compared the predictive abilities of <jats:styled-content style="fixed-case">TRUS</jats:styled-content> vs <jats:styled-content style="fixed-case">MRI</jats:styled-content> relative to intraoperative <jats:styled-content style="fixed-case">TRUS</jats:styled-content> (<jats:styled-content style="fixed-case">iTRUS</jats:styled-content>) to assess the role of mp<jats:styled-content style="fixed-case">MRI</jats:styled-content> in brachytherapy preplanning.</jats:p></jats:sec><jats:sec><jats:title>Materials and methods</jats:title><jats:p>Retrospective analysis was performed on 32 patients who underwent <jats:styled-content style="fixed-case">iTRUS</jats:styled-content>‐guided prostate <jats:styled-content style="fixed-case">LDR</jats:styled-content> brachytherapy as either mono‐ or combination therapy. 56.3% had <jats:styled-content style="fixed-case">pTRUS</jats:styled-content>‐only volume studies and 43.7% had both 3T‐mp<jats:styled-content style="fixed-case">MRI</jats:styled-content> and <jats:styled-content style="fixed-case">pTRUS</jats:styled-content> preplanning. <jats:styled-content style="fixed-case">MRI</jats:styled-content> was used for preplanning and its image fusion with <jats:styled-content style="fixed-case">iTRUS</jats:styled-content> was also used for intraoperative guidance of seed placement. Differences in gland volume, seed number, and activity and procedure time were examined, as well as the identification of lesions suspicious for tumor foci. Pearson correlation coefficient and Fisher's Z test were used to estimate associations between continuous measures.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>There was good correlation of planning volumes between <jats:styled-content style="fixed-case">iTRUS</jats:styled-content> and either <jats:styled-content style="fixed-case">pTRUS</jats:styled-content> or <jats:styled-content style="fixed-case">MRI</jats:styled-content> (<jats:italic>r</jats:italic> = 0.89, <jats:italic>r</jats:italic> = 0.77), not impacted by the addition of hormonal therapy (<jats:italic>P</jats:italic> = 0.65, <jats:italic>P</jats:italic> = 0.33). Both consistently predicted intraoperative seed number (<jats:italic>r</jats:italic> = 0.87, <jats:italic>r</jats:italic> = 0.86). <jats:styled-content style="fixed-case">MRI</jats:styled-content>/<jats:styled-content style="fixed-case">TRUS</jats:styled-content> fusion did not significantly increase surgical or anesthesia time (<jats:italic>P</jats:italic> = 0.10, <jats:italic>P</jats:italic> = 0.46). mp<jats:styled-content style="fixed-case">MRI</jats:styled-content> revealed suspicious focal lesions in 11 of 14 cases not visible on <jats:styled-content style="fixed-case">pTRUS</jats:styled-content>, that when correlated with histopathology, were incorporated into the plan.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Relative to <jats:styled-content style="fixed-case">pTRUS</jats:styled-content>,<jats:styled-content style="fixed-case"> MRI</jats:styled-content> yielded reliable preplanning measures, supporting the role of <jats:styled-content style="fixed-case">MRI</jats:styled-content>‐only <jats:styled-content style="fixed-case">LDR</jats:styled-content> treatment planning. mp<jats:styled-content style="fixed-case">MRI</jats:styled-content> carries numerous diagnostic, staging and preplanning advantages that facilitate better patient selection and delivery of novel dose escalation and targeted therapy, with no additional surgical or anesthesia time. Prospective studies assessing its impact on treatment planning and delivery can serve to establish mp<jats:styled-content style="fixed-case">MRI</jats:styled-content> as the standard of care in <jats:styled-content style="fixed-case">LDR</jats:styled-content> prostate brachytherapy planning.</jats:p></jats:sec> Comparison of multiparametric <scp>MRI</scp>‐based and transrectal ultrasound‐based preplans with intraoperative ultrasound‐based planning for low dose rate interstitial prostate seed implantation Journal of Applied Clinical Medical Physics |
| spellingShingle | Fredman, Elisha T., Traughber, Bryan J., Gross, Andrew, Podder, Tarun, Colussi, Valdir, Vinkler, Robert, Machtay, Mitchell, Ellis, Rodney J., Journal of Applied Clinical Medical Physics, Comparison of multiparametric MRI‐based and transrectal ultrasound‐based preplans with intraoperative ultrasound‐based planning for low dose rate interstitial prostate seed implantation, Radiology, Nuclear Medicine and imaging, Instrumentation, Radiation |
| title | Comparison of multiparametric MRI‐based and transrectal ultrasound‐based preplans with intraoperative ultrasound‐based planning for low dose rate interstitial prostate seed implantation |
| title_full | Comparison of multiparametric MRI‐based and transrectal ultrasound‐based preplans with intraoperative ultrasound‐based planning for low dose rate interstitial prostate seed implantation |
| title_fullStr | Comparison of multiparametric MRI‐based and transrectal ultrasound‐based preplans with intraoperative ultrasound‐based planning for low dose rate interstitial prostate seed implantation |
| title_full_unstemmed | Comparison of multiparametric MRI‐based and transrectal ultrasound‐based preplans with intraoperative ultrasound‐based planning for low dose rate interstitial prostate seed implantation |
| title_short | Comparison of multiparametric MRI‐based and transrectal ultrasound‐based preplans with intraoperative ultrasound‐based planning for low dose rate interstitial prostate seed implantation |
| title_sort | comparison of multiparametric <scp>mri</scp>‐based and transrectal ultrasound‐based preplans with intraoperative ultrasound‐based planning for low dose rate interstitial prostate seed implantation |
| title_unstemmed | Comparison of multiparametric MRI‐based and transrectal ultrasound‐based preplans with intraoperative ultrasound‐based planning for low dose rate interstitial prostate seed implantation |
| topic | Radiology, Nuclear Medicine and imaging, Instrumentation, Radiation |
| url | http://dx.doi.org/10.1002/acm2.12592 |