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Methylation‐Specific PCR
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| Zeitschriftentitel: | Current Protocols in Human Genetics |
|---|---|
| Personen und Körperschaften: | , |
| In: | Current Protocols in Human Genetics, 16, 1998, 1 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Wiley
|
| Schlagwörter: |
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Herman, James G. Baylin, Stephen B. Herman, James G. Baylin, Stephen B. |
|---|---|
| author |
Herman, James G. Baylin, Stephen B. |
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Herman, James G. Baylin, Stephen B. Current Protocols in Human Genetics Methylation‐Specific PCR Genetics Genetics (clinical) |
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herman, james g. |
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Herman, James G. Baylin, Stephen B. 1934-8266 1934-8258 Wiley Genetics Genetics (clinical) http://dx.doi.org/10.1002/0471142905.hg1006s16 <jats:title>Abstract</jats:title><jats:p>Methylationspecific PCR is a rapid method used to determine the methylation status of DNA. Not only does methylation affect the expression of genes in normal cells, but it is now known that disease processes such as cancer can result in abnormal DNA methylation patterns. Methylationspecific PCR can be used to investigate imprinted genes, to assess human tumors for clonality by studying genes inactivated on the X chromosome, and to examine abnormally methylated CpG islands in neoplasia.</jats:p> Methylation‐Specific PCR Current Protocols in Human Genetics |
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Wiley, 1998 |
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1998 |
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Current Protocols in Human Genetics |
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Methylation‐Specific PCR |
| title_unstemmed |
Methylation‐Specific PCR |
| title_full |
Methylation‐Specific PCR |
| title_fullStr |
Methylation‐Specific PCR |
| title_full_unstemmed |
Methylation‐Specific PCR |
| title_short |
Methylation‐Specific PCR |
| title_sort |
methylation‐specific pcr |
| topic |
Genetics Genetics (clinical) |
| url |
http://dx.doi.org/10.1002/0471142905.hg1006s16 |
| publishDate |
1998 |
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|
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<jats:title>Abstract</jats:title><jats:p>Methylationspecific PCR is a rapid method used to determine the methylation status of DNA. Not only does methylation affect the expression of genes in normal cells, but it is now known that disease processes such as cancer can result in abnormal DNA methylation patterns. Methylationspecific PCR can be used to investigate imprinted genes, to assess human tumors for clonality by studying genes inactivated on the X chromosome, and to examine abnormally methylated CpG islands in neoplasia.</jats:p> |
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| description | <jats:title>Abstract</jats:title><jats:p>Methylationspecific PCR is a rapid method used to determine the methylation status of DNA. Not only does methylation affect the expression of genes in normal cells, but it is now known that disease processes such as cancer can result in abnormal DNA methylation patterns. Methylationspecific PCR can be used to investigate imprinted genes, to assess human tumors for clonality by studying genes inactivated on the X chromosome, and to examine abnormally methylated CpG islands in neoplasia.</jats:p> |
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| imprint | Wiley, 1998 |
| imprint_str_mv | Wiley, 1998 |
| institution | DE-D275, DE-Bn3, DE-Brt1, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14, DE-Ch1, DE-L229 |
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| spelling | Herman, James G. Baylin, Stephen B. 1934-8266 1934-8258 Wiley Genetics Genetics (clinical) http://dx.doi.org/10.1002/0471142905.hg1006s16 <jats:title>Abstract</jats:title><jats:p>Methylationspecific PCR is a rapid method used to determine the methylation status of DNA. Not only does methylation affect the expression of genes in normal cells, but it is now known that disease processes such as cancer can result in abnormal DNA methylation patterns. Methylationspecific PCR can be used to investigate imprinted genes, to assess human tumors for clonality by studying genes inactivated on the X chromosome, and to examine abnormally methylated CpG islands in neoplasia.</jats:p> Methylation‐Specific PCR Current Protocols in Human Genetics |
| spellingShingle | Herman, James G., Baylin, Stephen B., Current Protocols in Human Genetics, Methylation‐Specific PCR, Genetics, Genetics (clinical) |
| title | Methylation‐Specific PCR |
| title_full | Methylation‐Specific PCR |
| title_fullStr | Methylation‐Specific PCR |
| title_full_unstemmed | Methylation‐Specific PCR |
| title_short | Methylation‐Specific PCR |
| title_sort | methylation‐specific pcr |
| title_unstemmed | Methylation‐Specific PCR |
| topic | Genetics, Genetics (clinical) |
| url | http://dx.doi.org/10.1002/0471142905.hg1006s16 |