author_facet Zhou, Jun
Yang, Cheng
Lu, Zhaoxiang
Zhang, Li
Yin, Yu
Tai, Sheng
Liang, Chaozhao
Zhou, Jun
Yang, Cheng
Lu, Zhaoxiang
Zhang, Li
Yin, Yu
Tai, Sheng
Liang, Chaozhao
author Zhou, Jun
Yang, Cheng
Lu, Zhaoxiang
Zhang, Li
Yin, Yu
Tai, Sheng
Liang, Chaozhao
spellingShingle Zhou, Jun
Yang, Cheng
Lu, Zhaoxiang
Zhang, Li
Yin, Yu
Tai, Sheng
Liang, Chaozhao
Medicine
Primary urothelial carcinoma of the prostate : A rare case report
General Medicine
author_sort zhou, jun
spelling Zhou, Jun Yang, Cheng Lu, Zhaoxiang Zhang, Li Yin, Yu Tai, Sheng Liang, Chaozhao 0025-7974 1536-5964 Ovid Technologies (Wolters Kluwer Health) General Medicine http://dx.doi.org/10.1097/md.0000000000014155 <jats:title>Abstract</jats:title> <jats:sec> <jats:title>Rationale:</jats:title> <jats:p>Prostatic urothelial carcinoma is a rare disease. Medical misdiagnosis rates remain high because there are no specific clinical symptoms or imaging features, which decreases patient survival. We report a case of prostatic urethral cancer confirmed by transrectal ultrasound-guided prostate biopsy because of an abnormal digital rectal exam.</jats:p> </jats:sec> <jats:sec> <jats:title>Patient concerns:</jats:title> <jats:p>A 55-year-old man was referred to our hospital due to lower urinary tract symptoms that lasted for 5 years.</jats:p> </jats:sec> <jats:sec> <jats:title>Diagnoses and Interventions:</jats:title> <jats:p>On digital rectal examination, a hard and enlarged prostate was detected. Computed tomography, bone scintigraphy, and magnetic resonance imaging indicated benign prostatic hyperplasia. The patient underwent transrectal ultrasound-guided prostate biopsy. From the histopathological examination and immunohistochemical markers, a diagnosis of high-grade prostatic urothelial carcinoma was made. We excluded the possibility of urothelial cancer originating in the bladder lining after transurethral resection of the bladder. Radical cystoprostatectomy was performed, followed by 6 cycles of cisplatin and gemcitabine chemotherapy. Postoperative pathology showed primary urothelial carcinoma of the prostate.</jats:p> </jats:sec> <jats:sec> <jats:title>Outcomes:</jats:title> <jats:p>The patient recovered smoothly after surgery. After a 6-month follow-up, no evidence of local recurrence or metastatic disease was found.</jats:p> </jats:sec> <jats:sec> <jats:title>Lessons:</jats:title> <jats:p>This case reminds clinicians that, for middle-aged men with suspicious digital rectal examinations, a diagnosis of prostatic urothelial carcinoma should be considered. Initial radical surgery followed by combination chemotherapy is suggested for therapeutic management.</jats:p> </jats:sec> A rare case report Primary urothelial carcinoma of the prostate : A rare case report Medicine
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title_sub A rare case report
title Primary urothelial carcinoma of the prostate : A rare case report
title_unstemmed Primary urothelial carcinoma of the prostate : A rare case report
title_full Primary urothelial carcinoma of the prostate : A rare case report
title_fullStr Primary urothelial carcinoma of the prostate : A rare case report
title_full_unstemmed Primary urothelial carcinoma of the prostate : A rare case report
title_short Primary urothelial carcinoma of the prostate : A rare case report
title_sort primary urothelial carcinoma of the prostate : a rare case report
topic General Medicine
url http://dx.doi.org/10.1097/md.0000000000014155
publishDate 2019
physical e14155
description <jats:title>Abstract</jats:title> <jats:sec> <jats:title>Rationale:</jats:title> <jats:p>Prostatic urothelial carcinoma is a rare disease. Medical misdiagnosis rates remain high because there are no specific clinical symptoms or imaging features, which decreases patient survival. We report a case of prostatic urethral cancer confirmed by transrectal ultrasound-guided prostate biopsy because of an abnormal digital rectal exam.</jats:p> </jats:sec> <jats:sec> <jats:title>Patient concerns:</jats:title> <jats:p>A 55-year-old man was referred to our hospital due to lower urinary tract symptoms that lasted for 5 years.</jats:p> </jats:sec> <jats:sec> <jats:title>Diagnoses and Interventions:</jats:title> <jats:p>On digital rectal examination, a hard and enlarged prostate was detected. Computed tomography, bone scintigraphy, and magnetic resonance imaging indicated benign prostatic hyperplasia. The patient underwent transrectal ultrasound-guided prostate biopsy. From the histopathological examination and immunohistochemical markers, a diagnosis of high-grade prostatic urothelial carcinoma was made. We excluded the possibility of urothelial cancer originating in the bladder lining after transurethral resection of the bladder. Radical cystoprostatectomy was performed, followed by 6 cycles of cisplatin and gemcitabine chemotherapy. Postoperative pathology showed primary urothelial carcinoma of the prostate.</jats:p> </jats:sec> <jats:sec> <jats:title>Outcomes:</jats:title> <jats:p>The patient recovered smoothly after surgery. After a 6-month follow-up, no evidence of local recurrence or metastatic disease was found.</jats:p> </jats:sec> <jats:sec> <jats:title>Lessons:</jats:title> <jats:p>This case reminds clinicians that, for middle-aged men with suspicious digital rectal examinations, a diagnosis of prostatic urothelial carcinoma should be considered. Initial radical surgery followed by combination chemotherapy is suggested for therapeutic management.</jats:p> </jats:sec>
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author Zhou, Jun, Yang, Cheng, Lu, Zhaoxiang, Zhang, Li, Yin, Yu, Tai, Sheng, Liang, Chaozhao
author_facet Zhou, Jun, Yang, Cheng, Lu, Zhaoxiang, Zhang, Li, Yin, Yu, Tai, Sheng, Liang, Chaozhao, Zhou, Jun, Yang, Cheng, Lu, Zhaoxiang, Zhang, Li, Yin, Yu, Tai, Sheng, Liang, Chaozhao
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description <jats:title>Abstract</jats:title> <jats:sec> <jats:title>Rationale:</jats:title> <jats:p>Prostatic urothelial carcinoma is a rare disease. Medical misdiagnosis rates remain high because there are no specific clinical symptoms or imaging features, which decreases patient survival. We report a case of prostatic urethral cancer confirmed by transrectal ultrasound-guided prostate biopsy because of an abnormal digital rectal exam.</jats:p> </jats:sec> <jats:sec> <jats:title>Patient concerns:</jats:title> <jats:p>A 55-year-old man was referred to our hospital due to lower urinary tract symptoms that lasted for 5 years.</jats:p> </jats:sec> <jats:sec> <jats:title>Diagnoses and Interventions:</jats:title> <jats:p>On digital rectal examination, a hard and enlarged prostate was detected. Computed tomography, bone scintigraphy, and magnetic resonance imaging indicated benign prostatic hyperplasia. The patient underwent transrectal ultrasound-guided prostate biopsy. From the histopathological examination and immunohistochemical markers, a diagnosis of high-grade prostatic urothelial carcinoma was made. We excluded the possibility of urothelial cancer originating in the bladder lining after transurethral resection of the bladder. Radical cystoprostatectomy was performed, followed by 6 cycles of cisplatin and gemcitabine chemotherapy. Postoperative pathology showed primary urothelial carcinoma of the prostate.</jats:p> </jats:sec> <jats:sec> <jats:title>Outcomes:</jats:title> <jats:p>The patient recovered smoothly after surgery. After a 6-month follow-up, no evidence of local recurrence or metastatic disease was found.</jats:p> </jats:sec> <jats:sec> <jats:title>Lessons:</jats:title> <jats:p>This case reminds clinicians that, for middle-aged men with suspicious digital rectal examinations, a diagnosis of prostatic urothelial carcinoma should be considered. Initial radical surgery followed by combination chemotherapy is suggested for therapeutic management.</jats:p> </jats:sec>
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spelling Zhou, Jun Yang, Cheng Lu, Zhaoxiang Zhang, Li Yin, Yu Tai, Sheng Liang, Chaozhao 0025-7974 1536-5964 Ovid Technologies (Wolters Kluwer Health) General Medicine http://dx.doi.org/10.1097/md.0000000000014155 <jats:title>Abstract</jats:title> <jats:sec> <jats:title>Rationale:</jats:title> <jats:p>Prostatic urothelial carcinoma is a rare disease. Medical misdiagnosis rates remain high because there are no specific clinical symptoms or imaging features, which decreases patient survival. We report a case of prostatic urethral cancer confirmed by transrectal ultrasound-guided prostate biopsy because of an abnormal digital rectal exam.</jats:p> </jats:sec> <jats:sec> <jats:title>Patient concerns:</jats:title> <jats:p>A 55-year-old man was referred to our hospital due to lower urinary tract symptoms that lasted for 5 years.</jats:p> </jats:sec> <jats:sec> <jats:title>Diagnoses and Interventions:</jats:title> <jats:p>On digital rectal examination, a hard and enlarged prostate was detected. Computed tomography, bone scintigraphy, and magnetic resonance imaging indicated benign prostatic hyperplasia. The patient underwent transrectal ultrasound-guided prostate biopsy. From the histopathological examination and immunohistochemical markers, a diagnosis of high-grade prostatic urothelial carcinoma was made. We excluded the possibility of urothelial cancer originating in the bladder lining after transurethral resection of the bladder. Radical cystoprostatectomy was performed, followed by 6 cycles of cisplatin and gemcitabine chemotherapy. Postoperative pathology showed primary urothelial carcinoma of the prostate.</jats:p> </jats:sec> <jats:sec> <jats:title>Outcomes:</jats:title> <jats:p>The patient recovered smoothly after surgery. After a 6-month follow-up, no evidence of local recurrence or metastatic disease was found.</jats:p> </jats:sec> <jats:sec> <jats:title>Lessons:</jats:title> <jats:p>This case reminds clinicians that, for middle-aged men with suspicious digital rectal examinations, a diagnosis of prostatic urothelial carcinoma should be considered. Initial radical surgery followed by combination chemotherapy is suggested for therapeutic management.</jats:p> </jats:sec> A rare case report Primary urothelial carcinoma of the prostate : A rare case report Medicine
spellingShingle Zhou, Jun, Yang, Cheng, Lu, Zhaoxiang, Zhang, Li, Yin, Yu, Tai, Sheng, Liang, Chaozhao, Medicine, Primary urothelial carcinoma of the prostate : A rare case report, General Medicine
title Primary urothelial carcinoma of the prostate : A rare case report
title_full Primary urothelial carcinoma of the prostate : A rare case report
title_fullStr Primary urothelial carcinoma of the prostate : A rare case report
title_full_unstemmed Primary urothelial carcinoma of the prostate : A rare case report
title_short Primary urothelial carcinoma of the prostate : A rare case report
title_sort primary urothelial carcinoma of the prostate : a rare case report
title_sub A rare case report
title_unstemmed Primary urothelial carcinoma of the prostate : A rare case report
topic General Medicine
url http://dx.doi.org/10.1097/md.0000000000014155