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Long noncoding RNA in cardiac aging and disease
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| Zeitschriftentitel: | Journal of Molecular Cell Biology |
|---|---|
| Personen und Körperschaften: | , , |
| In: | Journal of Molecular Cell Biology, 11, 2019, 10, S. 860-867 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Oxford University Press (OUP)
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| Schlagwörter: |
| author_facet |
Lozano-Vidal, Noelia Bink, Diewertje I Boon, Reinier A Lozano-Vidal, Noelia Bink, Diewertje I Boon, Reinier A |
|---|---|
| author |
Lozano-Vidal, Noelia Bink, Diewertje I Boon, Reinier A |
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Lozano-Vidal, Noelia Bink, Diewertje I Boon, Reinier A Journal of Molecular Cell Biology Long noncoding RNA in cardiac aging and disease Cell Biology Genetics Molecular Biology General Medicine |
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lozano-vidal, noelia |
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Lozano-Vidal, Noelia Bink, Diewertje I Boon, Reinier A 1759-4685 Oxford University Press (OUP) Cell Biology Genetics Molecular Biology General Medicine http://dx.doi.org/10.1093/jmcb/mjz046 <jats:title>Abstract</jats:title><jats:p>Cardiovascular diseases (CVDs) are the main cause of morbidity and mortality in Western society and present an important age-related risk. With the constant rise in life expectancy, prevalence of CVD in the population will likely increase further. New therapies, especially in the elderly, are needed to combat CVD. This review is focused on the role of long noncoding RNA (lncRNA) in CVD. RNA sequencing experiments in the past decade showed that most RNA does not code for protein, but many RNAs function as ncRNA. Here, we summarize the recent findings of lncRNA regulation in the diseased heart. The potential use of these RNAs as biomarkers of cardiac disease prediction is also discussed.</jats:p> Long noncoding RNA in cardiac aging and disease Journal of Molecular Cell Biology |
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Long noncoding RNA in cardiac aging and disease |
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Long noncoding RNA in cardiac aging and disease |
| title_full |
Long noncoding RNA in cardiac aging and disease |
| title_fullStr |
Long noncoding RNA in cardiac aging and disease |
| title_full_unstemmed |
Long noncoding RNA in cardiac aging and disease |
| title_short |
Long noncoding RNA in cardiac aging and disease |
| title_sort |
long noncoding rna in cardiac aging and disease |
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Cell Biology Genetics Molecular Biology General Medicine |
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2019 |
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860-867 |
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<jats:title>Abstract</jats:title><jats:p>Cardiovascular diseases (CVDs) are the main cause of morbidity and mortality in Western society and present an important age-related risk. With the constant rise in life expectancy, prevalence of CVD in the population will likely increase further. New therapies, especially in the elderly, are needed to combat CVD. This review is focused on the role of long noncoding RNA (lncRNA) in CVD. RNA sequencing experiments in the past decade showed that most RNA does not code for protein, but many RNAs function as ncRNA. Here, we summarize the recent findings of lncRNA regulation in the diseased heart. The potential use of these RNAs as biomarkers of cardiac disease prediction is also discussed.</jats:p> |
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| author | Lozano-Vidal, Noelia, Bink, Diewertje I, Boon, Reinier A |
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| description | <jats:title>Abstract</jats:title><jats:p>Cardiovascular diseases (CVDs) are the main cause of morbidity and mortality in Western society and present an important age-related risk. With the constant rise in life expectancy, prevalence of CVD in the population will likely increase further. New therapies, especially in the elderly, are needed to combat CVD. This review is focused on the role of long noncoding RNA (lncRNA) in CVD. RNA sequencing experiments in the past decade showed that most RNA does not code for protein, but many RNAs function as ncRNA. Here, we summarize the recent findings of lncRNA regulation in the diseased heart. The potential use of these RNAs as biomarkers of cardiac disease prediction is also discussed.</jats:p> |
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| spelling | Lozano-Vidal, Noelia Bink, Diewertje I Boon, Reinier A 1759-4685 Oxford University Press (OUP) Cell Biology Genetics Molecular Biology General Medicine http://dx.doi.org/10.1093/jmcb/mjz046 <jats:title>Abstract</jats:title><jats:p>Cardiovascular diseases (CVDs) are the main cause of morbidity and mortality in Western society and present an important age-related risk. With the constant rise in life expectancy, prevalence of CVD in the population will likely increase further. New therapies, especially in the elderly, are needed to combat CVD. This review is focused on the role of long noncoding RNA (lncRNA) in CVD. RNA sequencing experiments in the past decade showed that most RNA does not code for protein, but many RNAs function as ncRNA. Here, we summarize the recent findings of lncRNA regulation in the diseased heart. The potential use of these RNAs as biomarkers of cardiac disease prediction is also discussed.</jats:p> Long noncoding RNA in cardiac aging and disease Journal of Molecular Cell Biology |
| spellingShingle | Lozano-Vidal, Noelia, Bink, Diewertje I, Boon, Reinier A, Journal of Molecular Cell Biology, Long noncoding RNA in cardiac aging and disease, Cell Biology, Genetics, Molecular Biology, General Medicine |
| title | Long noncoding RNA in cardiac aging and disease |
| title_full | Long noncoding RNA in cardiac aging and disease |
| title_fullStr | Long noncoding RNA in cardiac aging and disease |
| title_full_unstemmed | Long noncoding RNA in cardiac aging and disease |
| title_short | Long noncoding RNA in cardiac aging and disease |
| title_sort | long noncoding rna in cardiac aging and disease |
| title_unstemmed | Long noncoding RNA in cardiac aging and disease |
| topic | Cell Biology, Genetics, Molecular Biology, General Medicine |
| url | http://dx.doi.org/10.1093/jmcb/mjz046 |