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A Green, Economic “Switch-On” Sensor for Cefixime Analysis Based on Black Soya Bean Carbon Quantum Dots
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| Zeitschriftentitel: | Journal of AOAC INTERNATIONAL |
|---|---|
| Personen und Körperschaften: | , , , , |
| In: | Journal of AOAC INTERNATIONAL, 103, 2020, 5, S. 1230-1236 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Oxford University Press (OUP)
|
| Schlagwörter: |
| author_facet |
Zhang, Yuecheng Wang, Jingyuan Wu, Wenbo Li, Chengjia Ma, Hongyan Zhang, Yuecheng Wang, Jingyuan Wu, Wenbo Li, Chengjia Ma, Hongyan |
|---|---|
| author |
Zhang, Yuecheng Wang, Jingyuan Wu, Wenbo Li, Chengjia Ma, Hongyan |
| spellingShingle |
Zhang, Yuecheng Wang, Jingyuan Wu, Wenbo Li, Chengjia Ma, Hongyan Journal of AOAC INTERNATIONAL A Green, Economic “Switch-On” Sensor for Cefixime Analysis Based on Black Soya Bean Carbon Quantum Dots Pharmacology Agronomy and Crop Science Environmental Chemistry Food Science Analytical Chemistry |
| author_sort |
zhang, yuecheng |
| spelling |
Zhang, Yuecheng Wang, Jingyuan Wu, Wenbo Li, Chengjia Ma, Hongyan 1060-3271 1944-7922 Oxford University Press (OUP) Pharmacology Agronomy and Crop Science Environmental Chemistry Food Science Analytical Chemistry http://dx.doi.org/10.1093/jaoacint/qsaa018 <jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background</jats:title> <jats:p>Cefixime is a third-generation oral cephalosporin antibiotic widely used to treat bacterial infections. Typical methods for cefixime analysis use expensive instruments or sophisticated experimental procedures, and thus a sensitive and practical method is urgently needed for cefixime detection and analysis.</jats:p> </jats:sec> <jats:sec> <jats:title>Objective</jats:title> <jats:p>To develop a sensitive and robust cefixime “switch-on” sensor based on carbon quantum dots (CQDs).</jats:p> </jats:sec> <jats:sec> <jats:title>Methods</jats:title> <jats:p>In this study, black soya beans were used as an inexpensive carbon source for a “green” synthesis of fluorescent black soya bean (BS)-carbon quantum dots (CQDs). The fluorescence of these particles could be efficiently quenched by Ce(IV)due to the ground state recombination and electron transfer (ET) between Ce(IV)and BS-CQDs. In the presence of cefixime, the ET was interrupted and the fluorescent signal was recovered.</jats:p> </jats:sec> <jats:sec> <jats:title>Results/Conclusions</jats:title> <jats:p>This method showed high sensitivity and an impressively low detection limit of 169 nM.</jats:p> </jats:sec> <jats:sec> <jats:title>Highlights</jats:title> <jats:p>This low-cost, simple strategy for cefixime detection exhibits excellent stability, selectivity, and sensitivity. Moreover, it was successfully applied for the detection of cefixime in tablets and in a complex biological environment, confirming its great potential utility for drug analysis, biological process research, and clinical research.</jats:p> </jats:sec> A Green, Economic “Switch-On” Sensor for Cefixime Analysis Based on Black Soya Bean Carbon Quantum Dots Journal of AOAC INTERNATIONAL |
| doi_str_mv |
10.1093/jaoacint/qsaa018 |
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Online |
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Chemie und Pharmazie Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft Technik |
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Oxford University Press (OUP), 2020 |
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1060-3271 1944-7922 |
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| title |
A Green, Economic “Switch-On” Sensor for Cefixime Analysis Based on Black Soya Bean Carbon Quantum Dots |
| title_unstemmed |
A Green, Economic “Switch-On” Sensor for Cefixime Analysis Based on Black Soya Bean Carbon Quantum Dots |
| title_full |
A Green, Economic “Switch-On” Sensor for Cefixime Analysis Based on Black Soya Bean Carbon Quantum Dots |
| title_fullStr |
A Green, Economic “Switch-On” Sensor for Cefixime Analysis Based on Black Soya Bean Carbon Quantum Dots |
| title_full_unstemmed |
A Green, Economic “Switch-On” Sensor for Cefixime Analysis Based on Black Soya Bean Carbon Quantum Dots |
| title_short |
A Green, Economic “Switch-On” Sensor for Cefixime Analysis Based on Black Soya Bean Carbon Quantum Dots |
| title_sort |
a green, economic “switch-on” sensor for cefixime analysis based on black soya bean carbon quantum dots |
| topic |
Pharmacology Agronomy and Crop Science Environmental Chemistry Food Science Analytical Chemistry |
| url |
http://dx.doi.org/10.1093/jaoacint/qsaa018 |
| publishDate |
2020 |
| physical |
1230-1236 |
| description |
<jats:title>Abstract</jats:title>
<jats:sec>
<jats:title>Background</jats:title>
<jats:p>Cefixime is a third-generation oral cephalosporin antibiotic widely used to treat bacterial infections. Typical methods for cefixime analysis use expensive instruments or sophisticated experimental procedures, and thus a sensitive and practical method is urgently needed for cefixime detection and analysis.</jats:p>
</jats:sec>
<jats:sec>
<jats:title>Objective</jats:title>
<jats:p>To develop a sensitive and robust cefixime “switch-on” sensor based on carbon quantum dots (CQDs).</jats:p>
</jats:sec>
<jats:sec>
<jats:title>Methods</jats:title>
<jats:p>In this study, black soya beans were used as an inexpensive carbon source for a “green” synthesis of fluorescent black soya bean (BS)-carbon quantum dots (CQDs). The fluorescence of these particles could be efficiently quenched by Ce(IV)due to the ground state recombination and electron transfer (ET) between Ce(IV)and BS-CQDs. In the presence of cefixime, the ET was interrupted and the fluorescent signal was recovered.</jats:p>
</jats:sec>
<jats:sec>
<jats:title>Results/Conclusions</jats:title>
<jats:p>This method showed high sensitivity and an impressively low detection limit of 169 nM.</jats:p>
</jats:sec>
<jats:sec>
<jats:title>Highlights</jats:title>
<jats:p>This low-cost, simple strategy for cefixime detection exhibits excellent stability, selectivity, and sensitivity. Moreover, it was successfully applied for the detection of cefixime in tablets and in a complex biological environment, confirming its great potential utility for drug analysis, biological process research, and clinical research.</jats:p>
</jats:sec> |
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| author | Zhang, Yuecheng, Wang, Jingyuan, Wu, Wenbo, Li, Chengjia, Ma, Hongyan |
| author_facet | Zhang, Yuecheng, Wang, Jingyuan, Wu, Wenbo, Li, Chengjia, Ma, Hongyan, Zhang, Yuecheng, Wang, Jingyuan, Wu, Wenbo, Li, Chengjia, Ma, Hongyan |
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| description | <jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background</jats:title> <jats:p>Cefixime is a third-generation oral cephalosporin antibiotic widely used to treat bacterial infections. Typical methods for cefixime analysis use expensive instruments or sophisticated experimental procedures, and thus a sensitive and practical method is urgently needed for cefixime detection and analysis.</jats:p> </jats:sec> <jats:sec> <jats:title>Objective</jats:title> <jats:p>To develop a sensitive and robust cefixime “switch-on” sensor based on carbon quantum dots (CQDs).</jats:p> </jats:sec> <jats:sec> <jats:title>Methods</jats:title> <jats:p>In this study, black soya beans were used as an inexpensive carbon source for a “green” synthesis of fluorescent black soya bean (BS)-carbon quantum dots (CQDs). The fluorescence of these particles could be efficiently quenched by Ce(IV)due to the ground state recombination and electron transfer (ET) between Ce(IV)and BS-CQDs. In the presence of cefixime, the ET was interrupted and the fluorescent signal was recovered.</jats:p> </jats:sec> <jats:sec> <jats:title>Results/Conclusions</jats:title> <jats:p>This method showed high sensitivity and an impressively low detection limit of 169 nM.</jats:p> </jats:sec> <jats:sec> <jats:title>Highlights</jats:title> <jats:p>This low-cost, simple strategy for cefixime detection exhibits excellent stability, selectivity, and sensitivity. Moreover, it was successfully applied for the detection of cefixime in tablets and in a complex biological environment, confirming its great potential utility for drug analysis, biological process research, and clinical research.</jats:p> </jats:sec> |
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| imprint_str_mv | Oxford University Press (OUP), 2020 |
| institution | DE-D275, DE-Bn3, DE-Brt1, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-14, DE-Ch1, DE-L229 |
| issn | 1060-3271, 1944-7922 |
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| physical | 1230-1236 |
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| spelling | Zhang, Yuecheng Wang, Jingyuan Wu, Wenbo Li, Chengjia Ma, Hongyan 1060-3271 1944-7922 Oxford University Press (OUP) Pharmacology Agronomy and Crop Science Environmental Chemistry Food Science Analytical Chemistry http://dx.doi.org/10.1093/jaoacint/qsaa018 <jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background</jats:title> <jats:p>Cefixime is a third-generation oral cephalosporin antibiotic widely used to treat bacterial infections. Typical methods for cefixime analysis use expensive instruments or sophisticated experimental procedures, and thus a sensitive and practical method is urgently needed for cefixime detection and analysis.</jats:p> </jats:sec> <jats:sec> <jats:title>Objective</jats:title> <jats:p>To develop a sensitive and robust cefixime “switch-on” sensor based on carbon quantum dots (CQDs).</jats:p> </jats:sec> <jats:sec> <jats:title>Methods</jats:title> <jats:p>In this study, black soya beans were used as an inexpensive carbon source for a “green” synthesis of fluorescent black soya bean (BS)-carbon quantum dots (CQDs). The fluorescence of these particles could be efficiently quenched by Ce(IV)due to the ground state recombination and electron transfer (ET) between Ce(IV)and BS-CQDs. In the presence of cefixime, the ET was interrupted and the fluorescent signal was recovered.</jats:p> </jats:sec> <jats:sec> <jats:title>Results/Conclusions</jats:title> <jats:p>This method showed high sensitivity and an impressively low detection limit of 169 nM.</jats:p> </jats:sec> <jats:sec> <jats:title>Highlights</jats:title> <jats:p>This low-cost, simple strategy for cefixime detection exhibits excellent stability, selectivity, and sensitivity. Moreover, it was successfully applied for the detection of cefixime in tablets and in a complex biological environment, confirming its great potential utility for drug analysis, biological process research, and clinical research.</jats:p> </jats:sec> A Green, Economic “Switch-On” Sensor for Cefixime Analysis Based on Black Soya Bean Carbon Quantum Dots Journal of AOAC INTERNATIONAL |
| spellingShingle | Zhang, Yuecheng, Wang, Jingyuan, Wu, Wenbo, Li, Chengjia, Ma, Hongyan, Journal of AOAC INTERNATIONAL, A Green, Economic “Switch-On” Sensor for Cefixime Analysis Based on Black Soya Bean Carbon Quantum Dots, Pharmacology, Agronomy and Crop Science, Environmental Chemistry, Food Science, Analytical Chemistry |
| title | A Green, Economic “Switch-On” Sensor for Cefixime Analysis Based on Black Soya Bean Carbon Quantum Dots |
| title_full | A Green, Economic “Switch-On” Sensor for Cefixime Analysis Based on Black Soya Bean Carbon Quantum Dots |
| title_fullStr | A Green, Economic “Switch-On” Sensor for Cefixime Analysis Based on Black Soya Bean Carbon Quantum Dots |
| title_full_unstemmed | A Green, Economic “Switch-On” Sensor for Cefixime Analysis Based on Black Soya Bean Carbon Quantum Dots |
| title_short | A Green, Economic “Switch-On” Sensor for Cefixime Analysis Based on Black Soya Bean Carbon Quantum Dots |
| title_sort | a green, economic “switch-on” sensor for cefixime analysis based on black soya bean carbon quantum dots |
| title_unstemmed | A Green, Economic “Switch-On” Sensor for Cefixime Analysis Based on Black Soya Bean Carbon Quantum Dots |
| topic | Pharmacology, Agronomy and Crop Science, Environmental Chemistry, Food Science, Analytical Chemistry |
| url | http://dx.doi.org/10.1093/jaoacint/qsaa018 |