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The role of cytochrome P450 enzymes in carcinogen activation and detoxication: an in vivo–in vitro paradox
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| Zeitschriftentitel: | Carcinogenesis |
|---|---|
| Personen und Körperschaften: | , , |
| In: | Carcinogenesis, 39, 2018, 7, S. 851-859 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Oxford University Press (OUP)
|
| Schlagwörter: |
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Reed, Lindsay Arlt, Volker M Phillips, David H Reed, Lindsay Arlt, Volker M Phillips, David H |
|---|---|
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Reed, Lindsay Arlt, Volker M Phillips, David H |
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Reed, Lindsay Arlt, Volker M Phillips, David H Carcinogenesis The role of cytochrome P450 enzymes in carcinogen activation and detoxication: an in vivo–in vitro paradox Cancer Research General Medicine |
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reed, lindsay |
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Reed, Lindsay Arlt, Volker M Phillips, David H 0143-3334 1460-2180 Oxford University Press (OUP) Cancer Research General Medicine http://dx.doi.org/10.1093/carcin/bgy058 <jats:p>Cytochrome P450 enzyme systems have been widely used in vitro to determine the pathways of activation of procarcinogens, but paradoxically, these same enzymes can play a more predominant role in carcinogen detoxification in vivo.</jats:p> The role of cytochrome P450 enzymes in carcinogen activation and detoxication: an in vivo–in vitro paradox Carcinogenesis |
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Oxford University Press (OUP), 2018 |
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| title |
The role of cytochrome P450 enzymes in carcinogen activation and detoxication: an in vivo–in vitro paradox |
| title_unstemmed |
The role of cytochrome P450 enzymes in carcinogen activation and detoxication: an in vivo–in vitro paradox |
| title_full |
The role of cytochrome P450 enzymes in carcinogen activation and detoxication: an in vivo–in vitro paradox |
| title_fullStr |
The role of cytochrome P450 enzymes in carcinogen activation and detoxication: an in vivo–in vitro paradox |
| title_full_unstemmed |
The role of cytochrome P450 enzymes in carcinogen activation and detoxication: an in vivo–in vitro paradox |
| title_short |
The role of cytochrome P450 enzymes in carcinogen activation and detoxication: an in vivo–in vitro paradox |
| title_sort |
the role of cytochrome p450 enzymes in carcinogen activation and detoxication: an in vivo–in vitro paradox |
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Cancer Research General Medicine |
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http://dx.doi.org/10.1093/carcin/bgy058 |
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2018 |
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851-859 |
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<jats:p>Cytochrome P450 enzyme systems have been widely used in vitro to determine the pathways of activation of procarcinogens, but paradoxically, these same enzymes can play a more predominant role in carcinogen detoxification in vivo.</jats:p> |
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| description | <jats:p>Cytochrome P450 enzyme systems have been widely used in vitro to determine the pathways of activation of procarcinogens, but paradoxically, these same enzymes can play a more predominant role in carcinogen detoxification in vivo.</jats:p> |
| doi_str_mv | 10.1093/carcin/bgy058 |
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| imprint | Oxford University Press (OUP), 2018 |
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| spelling | Reed, Lindsay Arlt, Volker M Phillips, David H 0143-3334 1460-2180 Oxford University Press (OUP) Cancer Research General Medicine http://dx.doi.org/10.1093/carcin/bgy058 <jats:p>Cytochrome P450 enzyme systems have been widely used in vitro to determine the pathways of activation of procarcinogens, but paradoxically, these same enzymes can play a more predominant role in carcinogen detoxification in vivo.</jats:p> The role of cytochrome P450 enzymes in carcinogen activation and detoxication: an in vivo–in vitro paradox Carcinogenesis |
| spellingShingle | Reed, Lindsay, Arlt, Volker M, Phillips, David H, Carcinogenesis, The role of cytochrome P450 enzymes in carcinogen activation and detoxication: an in vivo–in vitro paradox, Cancer Research, General Medicine |
| title | The role of cytochrome P450 enzymes in carcinogen activation and detoxication: an in vivo–in vitro paradox |
| title_full | The role of cytochrome P450 enzymes in carcinogen activation and detoxication: an in vivo–in vitro paradox |
| title_fullStr | The role of cytochrome P450 enzymes in carcinogen activation and detoxication: an in vivo–in vitro paradox |
| title_full_unstemmed | The role of cytochrome P450 enzymes in carcinogen activation and detoxication: an in vivo–in vitro paradox |
| title_short | The role of cytochrome P450 enzymes in carcinogen activation and detoxication: an in vivo–in vitro paradox |
| title_sort | the role of cytochrome p450 enzymes in carcinogen activation and detoxication: an in vivo–in vitro paradox |
| title_unstemmed | The role of cytochrome P450 enzymes in carcinogen activation and detoxication: an in vivo–in vitro paradox |
| topic | Cancer Research, General Medicine |
| url | http://dx.doi.org/10.1093/carcin/bgy058 |