author_facet Bunyan, J.
Green, J.
Diplock, A. T.
Robinson, D.
Bunyan, J.
Green, J.
Diplock, A. T.
Robinson, D.
author Bunyan, J.
Green, J.
Diplock, A. T.
Robinson, D.
spellingShingle Bunyan, J.
Green, J.
Diplock, A. T.
Robinson, D.
British Journal of Nutrition
Lysosomal enzymes and vitamin E deficiency : 3. Liver necrosis and testicular degeneration in the rat
Nutrition and Dietetics
Medicine (miscellaneous)
author_sort bunyan, j.
spelling Bunyan, J. Green, J. Diplock, A. T. Robinson, D. 0007-1145 1475-2662 Cambridge University Press (CUP) Nutrition and Dietetics Medicine (miscellaneous) http://dx.doi.org/10.1079/bjn19670015 <jats:p>1. The activities of several lysosomal hydrolases have been measured in tissues of rats with nutritional liver necrosis. Incipient or actual liver necrosis did not alter total, free or unsedimentable activities of cathepsin, β-glucuronidase, β-galactosidase or acid phosphatase of liver and kidney. Free hydrolytic activity towards p-nitrophenyl phosphate was slightly raised in liver, and serum β-galactosidase and β-glucuronidase were moderately elevated. These results suggest that lysosomal hydrolases are not directly implicated in the causation of liver necrosis.</jats:p><jats:p>2. Testicular degeneration was studied with reference to changes in β-giucuronidase activity. This enzyme activity, total, free and unsedimentable, was raised in deficient rat testis at 6 months old and did not decline even after a year. Raised values were also found in serum.</jats:p> 3. Liver necrosis and testicular degeneration in the rat Lysosomal enzymes and vitamin E deficiency : 3. Liver necrosis and testicular degeneration in the rat British Journal of Nutrition
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title_sub 3. Liver necrosis and testicular degeneration in the rat
title Lysosomal enzymes and vitamin E deficiency : 3. Liver necrosis and testicular degeneration in the rat
title_unstemmed Lysosomal enzymes and vitamin E deficiency : 3. Liver necrosis and testicular degeneration in the rat
title_full Lysosomal enzymes and vitamin E deficiency : 3. Liver necrosis and testicular degeneration in the rat
title_fullStr Lysosomal enzymes and vitamin E deficiency : 3. Liver necrosis and testicular degeneration in the rat
title_full_unstemmed Lysosomal enzymes and vitamin E deficiency : 3. Liver necrosis and testicular degeneration in the rat
title_short Lysosomal enzymes and vitamin E deficiency : 3. Liver necrosis and testicular degeneration in the rat
title_sort lysosomal enzymes and vitamin e deficiency : 3. liver necrosis and testicular degeneration in the rat
topic Nutrition and Dietetics
Medicine (miscellaneous)
url http://dx.doi.org/10.1079/bjn19670015
publishDate 1967
physical 147-154
description <jats:p>1. The activities of several lysosomal hydrolases have been measured in tissues of rats with nutritional liver necrosis. Incipient or actual liver necrosis did not alter total, free or unsedimentable activities of cathepsin, β-glucuronidase, β-galactosidase or acid phosphatase of liver and kidney. Free hydrolytic activity towards p-nitrophenyl phosphate was slightly raised in liver, and serum β-galactosidase and β-glucuronidase were moderately elevated. These results suggest that lysosomal hydrolases are not directly implicated in the causation of liver necrosis.</jats:p><jats:p>2. Testicular degeneration was studied with reference to changes in β-giucuronidase activity. This enzyme activity, total, free and unsedimentable, was raised in deficient rat testis at 6 months old and did not decline even after a year. Raised values were also found in serum.</jats:p>
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author Bunyan, J., Green, J., Diplock, A. T., Robinson, D.
author_facet Bunyan, J., Green, J., Diplock, A. T., Robinson, D., Bunyan, J., Green, J., Diplock, A. T., Robinson, D.
author_sort bunyan, j.
container_issue 1
container_start_page 147
container_title British Journal of Nutrition
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description <jats:p>1. The activities of several lysosomal hydrolases have been measured in tissues of rats with nutritional liver necrosis. Incipient or actual liver necrosis did not alter total, free or unsedimentable activities of cathepsin, β-glucuronidase, β-galactosidase or acid phosphatase of liver and kidney. Free hydrolytic activity towards p-nitrophenyl phosphate was slightly raised in liver, and serum β-galactosidase and β-glucuronidase were moderately elevated. These results suggest that lysosomal hydrolases are not directly implicated in the causation of liver necrosis.</jats:p><jats:p>2. Testicular degeneration was studied with reference to changes in β-giucuronidase activity. This enzyme activity, total, free and unsedimentable, was raised in deficient rat testis at 6 months old and did not decline even after a year. Raised values were also found in serum.</jats:p>
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spelling Bunyan, J. Green, J. Diplock, A. T. Robinson, D. 0007-1145 1475-2662 Cambridge University Press (CUP) Nutrition and Dietetics Medicine (miscellaneous) http://dx.doi.org/10.1079/bjn19670015 <jats:p>1. The activities of several lysosomal hydrolases have been measured in tissues of rats with nutritional liver necrosis. Incipient or actual liver necrosis did not alter total, free or unsedimentable activities of cathepsin, β-glucuronidase, β-galactosidase or acid phosphatase of liver and kidney. Free hydrolytic activity towards p-nitrophenyl phosphate was slightly raised in liver, and serum β-galactosidase and β-glucuronidase were moderately elevated. These results suggest that lysosomal hydrolases are not directly implicated in the causation of liver necrosis.</jats:p><jats:p>2. Testicular degeneration was studied with reference to changes in β-giucuronidase activity. This enzyme activity, total, free and unsedimentable, was raised in deficient rat testis at 6 months old and did not decline even after a year. Raised values were also found in serum.</jats:p> 3. Liver necrosis and testicular degeneration in the rat Lysosomal enzymes and vitamin E deficiency : 3. Liver necrosis and testicular degeneration in the rat British Journal of Nutrition
spellingShingle Bunyan, J., Green, J., Diplock, A. T., Robinson, D., British Journal of Nutrition, Lysosomal enzymes and vitamin E deficiency : 3. Liver necrosis and testicular degeneration in the rat, Nutrition and Dietetics, Medicine (miscellaneous)
title Lysosomal enzymes and vitamin E deficiency : 3. Liver necrosis and testicular degeneration in the rat
title_full Lysosomal enzymes and vitamin E deficiency : 3. Liver necrosis and testicular degeneration in the rat
title_fullStr Lysosomal enzymes and vitamin E deficiency : 3. Liver necrosis and testicular degeneration in the rat
title_full_unstemmed Lysosomal enzymes and vitamin E deficiency : 3. Liver necrosis and testicular degeneration in the rat
title_short Lysosomal enzymes and vitamin E deficiency : 3. Liver necrosis and testicular degeneration in the rat
title_sort lysosomal enzymes and vitamin e deficiency : 3. liver necrosis and testicular degeneration in the rat
title_sub 3. Liver necrosis and testicular degeneration in the rat
title_unstemmed Lysosomal enzymes and vitamin E deficiency : 3. Liver necrosis and testicular degeneration in the rat
topic Nutrition and Dietetics, Medicine (miscellaneous)
url http://dx.doi.org/10.1079/bjn19670015