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U2 region of Epstein-Barr virus DNA may encode Epstein-Barr nuclear antigen 2.
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| Zeitschriftentitel: | Proceedings of the National Academy of Sciences |
|---|---|
| Personen und Körperschaften: | , , , |
| In: | Proceedings of the National Academy of Sciences, 81, 1984, 23, S. 7632-7636 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
Proceedings of the National Academy of Sciences
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| Schlagwörter: |
| author_facet |
Dambaugh, T Hennessy, K Chamnankit, L Kieff, E Dambaugh, T Hennessy, K Chamnankit, L Kieff, E |
|---|---|
| author |
Dambaugh, T Hennessy, K Chamnankit, L Kieff, E |
| spellingShingle |
Dambaugh, T Hennessy, K Chamnankit, L Kieff, E Proceedings of the National Academy of Sciences U2 region of Epstein-Barr virus DNA may encode Epstein-Barr nuclear antigen 2. Multidisciplinary |
| author_sort |
dambaugh, t |
| spelling |
Dambaugh, T Hennessy, K Chamnankit, L Kieff, E 0027-8424 1091-6490 Proceedings of the National Academy of Sciences Multidisciplinary http://dx.doi.org/10.1073/pnas.81.23.7632 <jats:p>Sequence analysis of the U2 regions of the B95-8 and AG876 Epstein-Barr virus (EBV) isolates reveals divergence within a long open reading frame previously identified as encoding 1.5 kilobases of the 3' end of a viral RNA expressed in latently infected, growth-transformed, B-lymphocyte cell lines. Differences among EBV isolates within the U2 open reading frame are shown to correlate with differences in an EBV nuclear antigen, EBNA2. B95-8, W91, Raji, Cherry, and Lamont EBV isolates have similar U2 domains and encode similar-size EBNA2 proteins, while AG876, Jijoye, and P3HR-1 have variant or absent U2 domains and variant or absent EBNA2 proteins. The AG876 U2 open reading frame and EBNA2 protein are both shorter than those of B95-8. These data indicate that the U2 open reading frame encodes EBNA2.</jats:p> U2 region of Epstein-Barr virus DNA may encode Epstein-Barr nuclear antigen 2. Proceedings of the National Academy of Sciences |
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Proceedings of the National Academy of Sciences, 1984 |
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Proceedings of the National Academy of Sciences, 1984 |
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1984 |
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Proceedings of the National Academy of Sciences |
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Proceedings of the National Academy of Sciences |
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| title |
U2 region of Epstein-Barr virus DNA may encode Epstein-Barr nuclear antigen 2. |
| title_unstemmed |
U2 region of Epstein-Barr virus DNA may encode Epstein-Barr nuclear antigen 2. |
| title_full |
U2 region of Epstein-Barr virus DNA may encode Epstein-Barr nuclear antigen 2. |
| title_fullStr |
U2 region of Epstein-Barr virus DNA may encode Epstein-Barr nuclear antigen 2. |
| title_full_unstemmed |
U2 region of Epstein-Barr virus DNA may encode Epstein-Barr nuclear antigen 2. |
| title_short |
U2 region of Epstein-Barr virus DNA may encode Epstein-Barr nuclear antigen 2. |
| title_sort |
u2 region of epstein-barr virus dna may encode epstein-barr nuclear antigen 2. |
| topic |
Multidisciplinary |
| url |
http://dx.doi.org/10.1073/pnas.81.23.7632 |
| publishDate |
1984 |
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7632-7636 |
| description |
<jats:p>Sequence analysis of the U2 regions of the B95-8 and AG876 Epstein-Barr virus (EBV) isolates reveals divergence within a long open reading frame previously identified as encoding 1.5 kilobases of the 3' end of a viral RNA expressed in latently infected, growth-transformed, B-lymphocyte cell lines. Differences among EBV isolates within the U2 open reading frame are shown to correlate with differences in an EBV nuclear antigen, EBNA2. B95-8, W91, Raji, Cherry, and Lamont EBV isolates have similar U2 domains and encode similar-size EBNA2 proteins, while AG876, Jijoye, and P3HR-1 have variant or absent U2 domains and variant or absent EBNA2 proteins. The AG876 U2 open reading frame and EBNA2 protein are both shorter than those of B95-8. These data indicate that the U2 open reading frame encodes EBNA2.</jats:p> |
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| author | Dambaugh, T, Hennessy, K, Chamnankit, L, Kieff, E |
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| description | <jats:p>Sequence analysis of the U2 regions of the B95-8 and AG876 Epstein-Barr virus (EBV) isolates reveals divergence within a long open reading frame previously identified as encoding 1.5 kilobases of the 3' end of a viral RNA expressed in latently infected, growth-transformed, B-lymphocyte cell lines. Differences among EBV isolates within the U2 open reading frame are shown to correlate with differences in an EBV nuclear antigen, EBNA2. B95-8, W91, Raji, Cherry, and Lamont EBV isolates have similar U2 domains and encode similar-size EBNA2 proteins, while AG876, Jijoye, and P3HR-1 have variant or absent U2 domains and variant or absent EBNA2 proteins. The AG876 U2 open reading frame and EBNA2 protein are both shorter than those of B95-8. These data indicate that the U2 open reading frame encodes EBNA2.</jats:p> |
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| id | ai-49-aHR0cDovL2R4LmRvaS5vcmcvMTAuMTA3My9wbmFzLjgxLjIzLjc2MzI |
| imprint | Proceedings of the National Academy of Sciences, 1984 |
| imprint_str_mv | Proceedings of the National Academy of Sciences, 1984 |
| institution | DE-Ch1, DE-L229, DE-D275, DE-Bn3, DE-Brt1, DE-Zwi2, DE-D161, DE-Gla1, DE-Zi4, DE-15, DE-Pl11, DE-Rs1, DE-105, DE-14 |
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| last_indexed | 2024-03-01T17:15:59.953Z |
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| physical | 7632-7636 |
| publishDate | 1984 |
| publishDateSort | 1984 |
| publisher | Proceedings of the National Academy of Sciences |
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| series | Proceedings of the National Academy of Sciences |
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| spelling | Dambaugh, T Hennessy, K Chamnankit, L Kieff, E 0027-8424 1091-6490 Proceedings of the National Academy of Sciences Multidisciplinary http://dx.doi.org/10.1073/pnas.81.23.7632 <jats:p>Sequence analysis of the U2 regions of the B95-8 and AG876 Epstein-Barr virus (EBV) isolates reveals divergence within a long open reading frame previously identified as encoding 1.5 kilobases of the 3' end of a viral RNA expressed in latently infected, growth-transformed, B-lymphocyte cell lines. Differences among EBV isolates within the U2 open reading frame are shown to correlate with differences in an EBV nuclear antigen, EBNA2. B95-8, W91, Raji, Cherry, and Lamont EBV isolates have similar U2 domains and encode similar-size EBNA2 proteins, while AG876, Jijoye, and P3HR-1 have variant or absent U2 domains and variant or absent EBNA2 proteins. The AG876 U2 open reading frame and EBNA2 protein are both shorter than those of B95-8. These data indicate that the U2 open reading frame encodes EBNA2.</jats:p> U2 region of Epstein-Barr virus DNA may encode Epstein-Barr nuclear antigen 2. Proceedings of the National Academy of Sciences |
| spellingShingle | Dambaugh, T, Hennessy, K, Chamnankit, L, Kieff, E, Proceedings of the National Academy of Sciences, U2 region of Epstein-Barr virus DNA may encode Epstein-Barr nuclear antigen 2., Multidisciplinary |
| title | U2 region of Epstein-Barr virus DNA may encode Epstein-Barr nuclear antigen 2. |
| title_full | U2 region of Epstein-Barr virus DNA may encode Epstein-Barr nuclear antigen 2. |
| title_fullStr | U2 region of Epstein-Barr virus DNA may encode Epstein-Barr nuclear antigen 2. |
| title_full_unstemmed | U2 region of Epstein-Barr virus DNA may encode Epstein-Barr nuclear antigen 2. |
| title_short | U2 region of Epstein-Barr virus DNA may encode Epstein-Barr nuclear antigen 2. |
| title_sort | u2 region of epstein-barr virus dna may encode epstein-barr nuclear antigen 2. |
| title_unstemmed | U2 region of Epstein-Barr virus DNA may encode Epstein-Barr nuclear antigen 2. |
| topic | Multidisciplinary |
| url | http://dx.doi.org/10.1073/pnas.81.23.7632 |