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Electrophoretic stretching of DNA molecules using microscale T junctions
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| Zeitschriftentitel: | Applied Physics Letters |
|---|---|
| Personen und Körperschaften: | , |
| In: | Applied Physics Letters, 90, 2007, 22 |
| Format: | E-Article |
| Sprache: | Englisch |
| veröffentlicht: |
AIP Publishing
|
| Schlagwörter: |
| author_facet |
Tang, Jing Doyle, Patrick S. Tang, Jing Doyle, Patrick S. |
|---|---|
| author |
Tang, Jing Doyle, Patrick S. |
| spellingShingle |
Tang, Jing Doyle, Patrick S. Applied Physics Letters Electrophoretic stretching of DNA molecules using microscale T junctions Physics and Astronomy (miscellaneous) |
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tang, jing |
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Tang, Jing Doyle, Patrick S. 0003-6951 1077-3118 AIP Publishing Physics and Astronomy (miscellaneous) http://dx.doi.org/10.1063/1.2745650 <jats:p>Controlled trapping and stretching of DNA molecules are critical for single molecule genomic and polymer physics studies. The authors present a microfabricated T junction which can trap and stretch single free DNA molecules using electrophoretic forces. The device does not require special end functionalization of the DNA. They show that two physical mechanisms of stretching can occur depending on the length of the DNA relative to the channel width in the junction region. Stable trapping and stretching of DNA molecules up to lengths of 485kbp are demonstrated.</jats:p> Electrophoretic stretching of DNA molecules using microscale T junctions Applied Physics Letters |
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| title |
Electrophoretic stretching of DNA molecules using microscale T junctions |
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Electrophoretic stretching of DNA molecules using microscale T junctions |
| title_full |
Electrophoretic stretching of DNA molecules using microscale T junctions |
| title_fullStr |
Electrophoretic stretching of DNA molecules using microscale T junctions |
| title_full_unstemmed |
Electrophoretic stretching of DNA molecules using microscale T junctions |
| title_short |
Electrophoretic stretching of DNA molecules using microscale T junctions |
| title_sort |
electrophoretic stretching of dna molecules using microscale t junctions |
| topic |
Physics and Astronomy (miscellaneous) |
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http://dx.doi.org/10.1063/1.2745650 |
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2007 |
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<jats:p>Controlled trapping and stretching of DNA molecules are critical for single molecule genomic and polymer physics studies. The authors present a microfabricated T junction which can trap and stretch single free DNA molecules using electrophoretic forces. The device does not require special end functionalization of the DNA. They show that two physical mechanisms of stretching can occur depending on the length of the DNA relative to the channel width in the junction region. Stable trapping and stretching of DNA molecules up to lengths of 485kbp are demonstrated.</jats:p> |
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| author | Tang, Jing, Doyle, Patrick S. |
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| description | <jats:p>Controlled trapping and stretching of DNA molecules are critical for single molecule genomic and polymer physics studies. The authors present a microfabricated T junction which can trap and stretch single free DNA molecules using electrophoretic forces. The device does not require special end functionalization of the DNA. They show that two physical mechanisms of stretching can occur depending on the length of the DNA relative to the channel width in the junction region. Stable trapping and stretching of DNA molecules up to lengths of 485kbp are demonstrated.</jats:p> |
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| spelling | Tang, Jing Doyle, Patrick S. 0003-6951 1077-3118 AIP Publishing Physics and Astronomy (miscellaneous) http://dx.doi.org/10.1063/1.2745650 <jats:p>Controlled trapping and stretching of DNA molecules are critical for single molecule genomic and polymer physics studies. The authors present a microfabricated T junction which can trap and stretch single free DNA molecules using electrophoretic forces. The device does not require special end functionalization of the DNA. They show that two physical mechanisms of stretching can occur depending on the length of the DNA relative to the channel width in the junction region. Stable trapping and stretching of DNA molecules up to lengths of 485kbp are demonstrated.</jats:p> Electrophoretic stretching of DNA molecules using microscale T junctions Applied Physics Letters |
| spellingShingle | Tang, Jing, Doyle, Patrick S., Applied Physics Letters, Electrophoretic stretching of DNA molecules using microscale T junctions, Physics and Astronomy (miscellaneous) |
| title | Electrophoretic stretching of DNA molecules using microscale T junctions |
| title_full | Electrophoretic stretching of DNA molecules using microscale T junctions |
| title_fullStr | Electrophoretic stretching of DNA molecules using microscale T junctions |
| title_full_unstemmed | Electrophoretic stretching of DNA molecules using microscale T junctions |
| title_short | Electrophoretic stretching of DNA molecules using microscale T junctions |
| title_sort | electrophoretic stretching of dna molecules using microscale t junctions |
| title_unstemmed | Electrophoretic stretching of DNA molecules using microscale T junctions |
| topic | Physics and Astronomy (miscellaneous) |
| url | http://dx.doi.org/10.1063/1.2745650 |