author_facet Shen, C.‐P.
Wu, K. K.
Shearman, L. P.
Camacho, R.
Tota, M. R.
Fong, T. M.
Van der Ploeg, L. H. T.
Shen, C.‐P.
Wu, K. K.
Shearman, L. P.
Camacho, R.
Tota, M. R.
Fong, T. M.
Van der Ploeg, L. H. T.
author Shen, C.‐P.
Wu, K. K.
Shearman, L. P.
Camacho, R.
Tota, M. R.
Fong, T. M.
Van der Ploeg, L. H. T.
spellingShingle Shen, C.‐P.
Wu, K. K.
Shearman, L. P.
Camacho, R.
Tota, M. R.
Fong, T. M.
Van der Ploeg, L. H. T.
Journal of Neuroendocrinology
Plasma Agouti‐Related Protein Level: A Possible Correlation with Fasted and Fed States in Humans and Rats
Cellular and Molecular Neuroscience
Endocrine and Autonomic Systems
Endocrinology
Endocrinology, Diabetes and Metabolism
author_sort shen, c.‐p.
spelling Shen, C.‐P. Wu, K. K. Shearman, L. P. Camacho, R. Tota, M. R. Fong, T. M. Van der Ploeg, L. H. T. 0953-8194 1365-2826 Wiley Cellular and Molecular Neuroscience Endocrine and Autonomic Systems Endocrinology Endocrinology, Diabetes and Metabolism http://dx.doi.org/10.1046/j.1365-2826.2002.00825.x <jats:title>Abstract</jats:title><jats:p>We measured plasma concentrations of agouti‐related protein (AGRP) in humans and rats and determined whether these were affected by ingestion of a meal after fasting. In 17 healthy human subjects, the mean plasma concentration of AGRP was lower in the fed state than in the fasted state. Two hours after a breakfast meal, AGRP levels dropped by 39%. By contrast, a continued fast for 2 h increased the average AGRP concentration by 73%. In rats with diet‐induced obesity, refeeding resulted in a 50% decrease in plasma AGRP concentrations following a fasting‐refeeding protocol. Our results support the notion that plasma AGRP may serve as a biomarker for the transition from a fasted to the satiated state.</jats:p> Plasma Agouti‐Related Protein Level: A Possible Correlation with Fasted and Fed States in Humans and Rats Journal of Neuroendocrinology
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series Journal of Neuroendocrinology
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title Plasma Agouti‐Related Protein Level: A Possible Correlation with Fasted and Fed States in Humans and Rats
title_unstemmed Plasma Agouti‐Related Protein Level: A Possible Correlation with Fasted and Fed States in Humans and Rats
title_full Plasma Agouti‐Related Protein Level: A Possible Correlation with Fasted and Fed States in Humans and Rats
title_fullStr Plasma Agouti‐Related Protein Level: A Possible Correlation with Fasted and Fed States in Humans and Rats
title_full_unstemmed Plasma Agouti‐Related Protein Level: A Possible Correlation with Fasted and Fed States in Humans and Rats
title_short Plasma Agouti‐Related Protein Level: A Possible Correlation with Fasted and Fed States in Humans and Rats
title_sort plasma agouti‐related protein level: a possible correlation with fasted and fed states in humans and rats
topic Cellular and Molecular Neuroscience
Endocrine and Autonomic Systems
Endocrinology
Endocrinology, Diabetes and Metabolism
url http://dx.doi.org/10.1046/j.1365-2826.2002.00825.x
publishDate 2002
physical 607-610
description <jats:title>Abstract</jats:title><jats:p>We measured plasma concentrations of agouti‐related protein (AGRP) in humans and rats and determined whether these were affected by ingestion of a meal after fasting. In 17 healthy human subjects, the mean plasma concentration of AGRP was lower in the fed state than in the fasted state. Two hours after a breakfast meal, AGRP levels dropped by 39%. By contrast, a continued fast for 2 h increased the average AGRP concentration by 73%. In rats with diet‐induced obesity, refeeding resulted in a 50% decrease in plasma AGRP concentrations following a fasting‐refeeding protocol. Our results support the notion that plasma AGRP may serve as a biomarker for the transition from a fasted to the satiated state.</jats:p>
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author Shen, C.‐P., Wu, K. K., Shearman, L. P., Camacho, R., Tota, M. R., Fong, T. M., Van der Ploeg, L. H. T.
author_facet Shen, C.‐P., Wu, K. K., Shearman, L. P., Camacho, R., Tota, M. R., Fong, T. M., Van der Ploeg, L. H. T., Shen, C.‐P., Wu, K. K., Shearman, L. P., Camacho, R., Tota, M. R., Fong, T. M., Van der Ploeg, L. H. T.
author_sort shen, c.‐p.
container_issue 8
container_start_page 607
container_title Journal of Neuroendocrinology
container_volume 14
description <jats:title>Abstract</jats:title><jats:p>We measured plasma concentrations of agouti‐related protein (AGRP) in humans and rats and determined whether these were affected by ingestion of a meal after fasting. In 17 healthy human subjects, the mean plasma concentration of AGRP was lower in the fed state than in the fasted state. Two hours after a breakfast meal, AGRP levels dropped by 39%. By contrast, a continued fast for 2 h increased the average AGRP concentration by 73%. In rats with diet‐induced obesity, refeeding resulted in a 50% decrease in plasma AGRP concentrations following a fasting‐refeeding protocol. Our results support the notion that plasma AGRP may serve as a biomarker for the transition from a fasted to the satiated state.</jats:p>
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publisher Wiley
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series Journal of Neuroendocrinology
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spelling Shen, C.‐P. Wu, K. K. Shearman, L. P. Camacho, R. Tota, M. R. Fong, T. M. Van der Ploeg, L. H. T. 0953-8194 1365-2826 Wiley Cellular and Molecular Neuroscience Endocrine and Autonomic Systems Endocrinology Endocrinology, Diabetes and Metabolism http://dx.doi.org/10.1046/j.1365-2826.2002.00825.x <jats:title>Abstract</jats:title><jats:p>We measured plasma concentrations of agouti‐related protein (AGRP) in humans and rats and determined whether these were affected by ingestion of a meal after fasting. In 17 healthy human subjects, the mean plasma concentration of AGRP was lower in the fed state than in the fasted state. Two hours after a breakfast meal, AGRP levels dropped by 39%. By contrast, a continued fast for 2 h increased the average AGRP concentration by 73%. In rats with diet‐induced obesity, refeeding resulted in a 50% decrease in plasma AGRP concentrations following a fasting‐refeeding protocol. Our results support the notion that plasma AGRP may serve as a biomarker for the transition from a fasted to the satiated state.</jats:p> Plasma Agouti‐Related Protein Level: A Possible Correlation with Fasted and Fed States in Humans and Rats Journal of Neuroendocrinology
spellingShingle Shen, C.‐P., Wu, K. K., Shearman, L. P., Camacho, R., Tota, M. R., Fong, T. M., Van der Ploeg, L. H. T., Journal of Neuroendocrinology, Plasma Agouti‐Related Protein Level: A Possible Correlation with Fasted and Fed States in Humans and Rats, Cellular and Molecular Neuroscience, Endocrine and Autonomic Systems, Endocrinology, Endocrinology, Diabetes and Metabolism
title Plasma Agouti‐Related Protein Level: A Possible Correlation with Fasted and Fed States in Humans and Rats
title_full Plasma Agouti‐Related Protein Level: A Possible Correlation with Fasted and Fed States in Humans and Rats
title_fullStr Plasma Agouti‐Related Protein Level: A Possible Correlation with Fasted and Fed States in Humans and Rats
title_full_unstemmed Plasma Agouti‐Related Protein Level: A Possible Correlation with Fasted and Fed States in Humans and Rats
title_short Plasma Agouti‐Related Protein Level: A Possible Correlation with Fasted and Fed States in Humans and Rats
title_sort plasma agouti‐related protein level: a possible correlation with fasted and fed states in humans and rats
title_unstemmed Plasma Agouti‐Related Protein Level: A Possible Correlation with Fasted and Fed States in Humans and Rats
topic Cellular and Molecular Neuroscience, Endocrine and Autonomic Systems, Endocrinology, Endocrinology, Diabetes and Metabolism
url http://dx.doi.org/10.1046/j.1365-2826.2002.00825.x