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Applications of RNA-Seq in Biology and Medicine
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| Personen und Körperschaften: | |
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| Titel: | Applications of RNA-Seq in Biology and Medicine |
| Format: | E-Book |
| Sprache: | Englisch |
| veröffentlicht: |
[Erscheinungsort nicht ermittelbar]
IntechOpen
2021
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| Schlagwörter: | |
| Quelle: | Verbunddaten SWB Lizenzfreie Online-Ressourcen |
| Anmerkungen: | English |
| Zugangsinformationen: | Elektronischer Volltext - Open Access |
| Zusammenfassung: | This book evaluates and comprehensively summarizes the scientific findings that have been achieved through RNA-sequencing (RNA-Seq) technology. RNA-Seq transcriptome profiling of healthy and diseased tissues allows FOR understanding the alterations in cellular phenotypes through the expression of differentially spliced RNA isoforms. Assessment of gene expression by RNA-Seq provides new insight into host response to pathogens, drugs, allergens, and other environmental triggers. RNA-Seq allows us to accurately capture all subtypes of RNA molecules, in any sequenced organism or single-cell type, under different experimental conditions. Merging genomics and transcriptomic profiling provides novel information underlying causative DNA mutations. Combining RNA-Seq with immunoprecipitation and cross-linking techniques is a clever multi-omics strategy assessing transcriptional, post-transcriptional and post-translational levels of gene expression regulation |
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| Umfang: | 1 Online-Ressource (142 p.) |
| ISBN: |
9781839628153
9781839626869 9781839628160 1839628162 1839626860 1839628154 |
| Zugang: | Open Access |
| Anmerkungen: | English |