author_facet Eze, Peter M.
Abonyi, Dominic O.
Abba, Chika C.
Proksch, Peter
Okoye, Festus B. C.
Esimone, Charles O.
Eze, Peter M.
Abonyi, Dominic O.
Abba, Chika C.
Proksch, Peter
Okoye, Festus B. C.
Esimone, Charles O.
author Eze, Peter M.
Abonyi, Dominic O.
Abba, Chika C.
Proksch, Peter
Okoye, Festus B. C.
Esimone, Charles O.
spellingShingle Eze, Peter M.
Abonyi, Dominic O.
Abba, Chika C.
Proksch, Peter
Okoye, Festus B. C.
Esimone, Charles O.
The EuroBiotech Journal
Toxic, but beneficial compounds from endophytic fungi of Carica papaya
Genetics
Molecular Biology
Biomedical Engineering
Molecular Medicine
Food Science
Biotechnology
author_sort eze, peter m.
spelling Eze, Peter M. Abonyi, Dominic O. Abba, Chika C. Proksch, Peter Okoye, Festus B. C. Esimone, Charles O. 2564-615X Walter de Gruyter GmbH Genetics Molecular Biology Biomedical Engineering Molecular Medicine Food Science Biotechnology http://dx.doi.org/10.2478/ebtj-2019-0012 <jats:title>Abstract</jats:title> <jats:p>Fungi remain a promising source of novel biologically active compounds with potentials in drug discovery and development. This study was aimed at investigating the secondary metabolites from endophytic <jats:italic>Fusarium equiseti</jats:italic> and <jats:italic>Epicoccum sorghinum</jats:italic> associated with leaves of <jats:italic>Carica papaya</jats:italic> collected from Agulu, Anambra State, Nigeria. Isolation of the endophytic fungi, taxonomic identification, fermentation, extraction and isolation of fungal secondary metabolites were carried out using standard procedures. Chromatographic separation and spectroscopic analyses of the fungal secondary metabolites yielded three toxigenic compounds - equisetin and its epimer 5’- epiequisetin from <jats:italic>F. equiseti</jats:italic> and tenuazonic acid from <jats:italic>E. sorghinum</jats:italic> These compounds are known to possess several beneficial biological properties that can be explored for pharmaceutical, agricultural or industrial purposes.</jats:p> Toxic, but beneficial compounds from endophytic fungi of <i>Carica papaya</i> The EuroBiotech Journal
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title Toxic, but beneficial compounds from endophytic fungi of Carica papaya
title_unstemmed Toxic, but beneficial compounds from endophytic fungi of Carica papaya
title_full Toxic, but beneficial compounds from endophytic fungi of Carica papaya
title_fullStr Toxic, but beneficial compounds from endophytic fungi of Carica papaya
title_full_unstemmed Toxic, but beneficial compounds from endophytic fungi of Carica papaya
title_short Toxic, but beneficial compounds from endophytic fungi of Carica papaya
title_sort toxic, but beneficial compounds from endophytic fungi of <i>carica papaya</i>
topic Genetics
Molecular Biology
Biomedical Engineering
Molecular Medicine
Food Science
Biotechnology
url http://dx.doi.org/10.2478/ebtj-2019-0012
publishDate 2019
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description <jats:title>Abstract</jats:title> <jats:p>Fungi remain a promising source of novel biologically active compounds with potentials in drug discovery and development. This study was aimed at investigating the secondary metabolites from endophytic <jats:italic>Fusarium equiseti</jats:italic> and <jats:italic>Epicoccum sorghinum</jats:italic> associated with leaves of <jats:italic>Carica papaya</jats:italic> collected from Agulu, Anambra State, Nigeria. Isolation of the endophytic fungi, taxonomic identification, fermentation, extraction and isolation of fungal secondary metabolites were carried out using standard procedures. Chromatographic separation and spectroscopic analyses of the fungal secondary metabolites yielded three toxigenic compounds - equisetin and its epimer 5’- epiequisetin from <jats:italic>F. equiseti</jats:italic> and tenuazonic acid from <jats:italic>E. sorghinum</jats:italic> These compounds are known to possess several beneficial biological properties that can be explored for pharmaceutical, agricultural or industrial purposes.</jats:p>
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author Eze, Peter M., Abonyi, Dominic O., Abba, Chika C., Proksch, Peter, Okoye, Festus B. C., Esimone, Charles O.
author_facet Eze, Peter M., Abonyi, Dominic O., Abba, Chika C., Proksch, Peter, Okoye, Festus B. C., Esimone, Charles O., Eze, Peter M., Abonyi, Dominic O., Abba, Chika C., Proksch, Peter, Okoye, Festus B. C., Esimone, Charles O.
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description <jats:title>Abstract</jats:title> <jats:p>Fungi remain a promising source of novel biologically active compounds with potentials in drug discovery and development. This study was aimed at investigating the secondary metabolites from endophytic <jats:italic>Fusarium equiseti</jats:italic> and <jats:italic>Epicoccum sorghinum</jats:italic> associated with leaves of <jats:italic>Carica papaya</jats:italic> collected from Agulu, Anambra State, Nigeria. Isolation of the endophytic fungi, taxonomic identification, fermentation, extraction and isolation of fungal secondary metabolites were carried out using standard procedures. Chromatographic separation and spectroscopic analyses of the fungal secondary metabolites yielded three toxigenic compounds - equisetin and its epimer 5’- epiequisetin from <jats:italic>F. equiseti</jats:italic> and tenuazonic acid from <jats:italic>E. sorghinum</jats:italic> These compounds are known to possess several beneficial biological properties that can be explored for pharmaceutical, agricultural or industrial purposes.</jats:p>
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spelling Eze, Peter M. Abonyi, Dominic O. Abba, Chika C. Proksch, Peter Okoye, Festus B. C. Esimone, Charles O. 2564-615X Walter de Gruyter GmbH Genetics Molecular Biology Biomedical Engineering Molecular Medicine Food Science Biotechnology http://dx.doi.org/10.2478/ebtj-2019-0012 <jats:title>Abstract</jats:title> <jats:p>Fungi remain a promising source of novel biologically active compounds with potentials in drug discovery and development. This study was aimed at investigating the secondary metabolites from endophytic <jats:italic>Fusarium equiseti</jats:italic> and <jats:italic>Epicoccum sorghinum</jats:italic> associated with leaves of <jats:italic>Carica papaya</jats:italic> collected from Agulu, Anambra State, Nigeria. Isolation of the endophytic fungi, taxonomic identification, fermentation, extraction and isolation of fungal secondary metabolites were carried out using standard procedures. Chromatographic separation and spectroscopic analyses of the fungal secondary metabolites yielded three toxigenic compounds - equisetin and its epimer 5’- epiequisetin from <jats:italic>F. equiseti</jats:italic> and tenuazonic acid from <jats:italic>E. sorghinum</jats:italic> These compounds are known to possess several beneficial biological properties that can be explored for pharmaceutical, agricultural or industrial purposes.</jats:p> Toxic, but beneficial compounds from endophytic fungi of <i>Carica papaya</i> The EuroBiotech Journal
spellingShingle Eze, Peter M., Abonyi, Dominic O., Abba, Chika C., Proksch, Peter, Okoye, Festus B. C., Esimone, Charles O., The EuroBiotech Journal, Toxic, but beneficial compounds from endophytic fungi of Carica papaya, Genetics, Molecular Biology, Biomedical Engineering, Molecular Medicine, Food Science, Biotechnology
title Toxic, but beneficial compounds from endophytic fungi of Carica papaya
title_full Toxic, but beneficial compounds from endophytic fungi of Carica papaya
title_fullStr Toxic, but beneficial compounds from endophytic fungi of Carica papaya
title_full_unstemmed Toxic, but beneficial compounds from endophytic fungi of Carica papaya
title_short Toxic, but beneficial compounds from endophytic fungi of Carica papaya
title_sort toxic, but beneficial compounds from endophytic fungi of <i>carica papaya</i>
title_unstemmed Toxic, but beneficial compounds from endophytic fungi of Carica papaya
topic Genetics, Molecular Biology, Biomedical Engineering, Molecular Medicine, Food Science, Biotechnology
url http://dx.doi.org/10.2478/ebtj-2019-0012